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T81140SNM1A-IN-1;化合物 SNM1A-IN-1SNM1A-IN-1
SNM1A-IN-1 (compound 11a) serves as an inhibitor of the DNA damage repair enzyme SNM1A, exhibiting cytotoxic properties [1].
价 格:¥电议型 号:T81140产 地:中国大陆
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T80633Androgen receptor degrader-1;化合物 Androgen receptor degrader-1Androgen receptor degrader-1
Androgen Receptor Degrader-1 (Compound 18) is a potent agent for androgen receptor degradation, applicable in cancer research [1].
价 格:¥电议型 号:T80633产 地:中国大陆
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T80600Peginterferon lambda-1a;化合物 Peginterferon lambda-1aBMS-914143;BMS-914143
Peginterferon lambda-1a (BMS-914143) is a monoclonal antibody that targets IFNLR1 and is composed of IFNL1 conjugated to pegol [1].
价 格:¥电议型 号:T80600产 地:中国大陆
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T80586Anti-Mouse IL-1a Antibody (ALF-161);化合物 Anti-Mouse IL-1a Antibody (ALF-161)Anti-Mouse IL-1a Antibody
Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.
价 格:¥电议型 号:T80586产 地:中国大陆
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T80494Tap1a;化合物 Tap1aTRTX-Tap1a|||Theraphotoxin-Tap1a|||?/ω-TRTX-Tap1a;TRTX-Tap1a|||Theraphotoxin-Tap1a|||
Theraphotoxin-Tap1a (Tap1a) is a spider venom-derived peptide that acts as an inhibitor of sodium channels, displaying IC50 values of 80 nM for Na v 1.7 and 301 nM for Na v 1.1. It demonstrates analgesic effects [1].
价 格:¥电议型 号:T80494产 地:中国大陆
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T80452Ceratotoxin-1;化合物 Ceratotoxin-1CcoTx1|||β-TRTX-cm1a;CcoTx1|||β-TRTX-cm1a
Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes. It selectively inhibits Nav1.1/β1, Nav1.2/β1, Nav1.4/β1, and Nav1.5/β1 with IC50 values of 523 nM, 3 nM, 888 nM, and 323 nM, respectively. Additionally, Ceratotoxin-1 is known to inhibit Nav1.8/β1 [1].
价 格:¥电议型 号:T80452产 地:中国大陆
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T80445Phlo1a;化合物 Phlo1aμ-TrTx-Phlo1a;μ-TrTx-Phlo1a
Phlo1a (μ-TrTx-Phlo1a), a 35-amino acid peptide toxin, demonstrates a weak inhibitory effect on Nav1.2 and Nav1.5 channels [1]. Meanwhile, Phlo1b acts as a selective inhibitor of the Nav1.7 channel.
价 格:¥电议型 号:T80445产 地:中国大陆
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T80437μ-TRTX-Hd1a;化合物 μ-TRTX-Hd1aμ-TRTX-Hd1a
μ-TRTX-Hd1a, a spider venom-derived compound, selectively inhibits the human NaV 1.7 channel by functioning as a gating modifier. It interacts with the S3b-S4 paddle motif within domain II of the channel [1].
价 格:¥电议型 号:T80437产 地:中国大陆
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T80433δ-Buthitoxin-Hj1a;化合物 δ-Buthitoxin-Hj1aδ-Buthitoxin-Hj1a
δ-Buthitoxin-Hj1a, a scorpion-venom peptide, functions as a potent agonist for the NaV1.1 channel, exhibiting an EC50 value of 17 nM. It can be employed in research pertaining to Dravet syndrome (DS) [1].
价 格:¥电议型 号:T80433产 地:中国大陆
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T80431δ-Theraphotoxin-Hm1a toxin;化合物 δ-Theraphotoxin-Hm1a toxinδ-Theraphotoxin-Hm1a toxin
δ-Theraphotoxin-Hm1a is a selective NaV1.1 activator that induces pain and touch sensitivity, with potential applications in irritable bowel syndrome research [1].
价 格:¥电议型 号:T80431产 地:中国大陆
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T80414ASP-1;化合物 ASP-1ASP-1
ASP-1 is a potent antistaphylococcal peptide, exhibiting minimum inhibitory concentrations (MICs) ranging from 2 μg/mL to 64 μg/mL against both S. aureus and methicillin-resistant S. aureus (MRSA) [1].
价 格:¥电议型 号:T80414产 地:中国大陆
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T80406Aurein 1.1;化合物 Aurein 1.1Aurein 1.1
Aurein 1.1, an antibiotic peptide, originates from Australian Bell Frogs (Litoria raniformis) [1].
价 格:¥电议型 号:T80406产 地:中国大陆
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T80404Aurein 2.1;化合物 Aurein 2.1Aurein 2.1
Aurein 2.1, an antibiotic peptide, is found in Litoria aurea and Litoria raniformis, commonly known as Australian Bell Frogs [1].
价 格:¥电议型 号:T80404产 地:中国大陆
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T80346Tur1A;化合物 Tur1ATur1A
Tur1A, an antimicrobial peptide sourced from the bottlenose dolphin (Tursiops truncates), impedes bacterial protein synthesis. It achieves this inhibition by attaching to ribosomes and obstructing the progression from the initiation phase to the elongation phase [1].
价 格:¥电议型 号:T80346产 地:中国大陆
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T80305A8SGLP-1;化合物 A8SGLP-1A8SGLP-1
A8SGLP-1, an orally active GLP-1 analogue, features serine substituted for alanine at position 8. It effectively reduces blood glucose in db/db mice, maintaining its function [1].
价 格:¥电议型 号:T80305产 地:中国大陆
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T80301Aurein 3.1;化合物 Aurein 3.1Aurein 3.1
Aurein 3.1 is an antibiotic antimicrobial peptide, whereas Aurein 2.6 demonstrates activity against Gram-positive bacteria, exhibiting minimum inhibitory concentrations (MIC) of 80 μM for M. luteus and 50 μM for S. aureus, S. epidermis, S. mutans, and B. subtilis [1] [2].
价 格:¥电议型 号:T80301产 地:中国大陆
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T80188Hm1a;化合物 Hm1aHm1a
Hm1a, a disulfide-rich spider-venom peptide and NaV1.1 activator, reestablishes the function of inhibitory interneurons in a Dravet syndrome (DS) mouse model [1].
价 格:¥电议型 号:T80188产 地:中国大陆
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T80178Dc1a;化合物 Dc1aDc1a
Dc1a, a toxin isolated from the desert bush spider Diguetia canities [1], potently facilitates the opening of the German cockroach Na v channel (BgNa v 1).
价 格:¥电议型 号:T80178产 地:中国大陆
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T80169ProTx-III;化合物 ProTx-IIIμ-TRTX-Tp1a;μ-TRTX-Tp1a
ProTx-III, a spider venom peptide derived from the Peruvian green velvet tarantula, functions as a selective and potent inhibitor of the voltage-gated sodium channel Na v 1.7, exhibiting an IC 50 of 2.1 nM. Characterized by its inhibitor cystine knot motif (ICK), ProTx-III can attenuate the pain response and is applicable in research on chronic pain, epilepsy, and arrhythmia [1].
价 格:¥电议型 号:T80169产 地:中国大陆
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T80160ω-Hexatoxin-Hv1a;化合物 ω-Hexatoxin-Hv1aω-ACTX-Hv1|||ω-Atracotoxin-HV1;ω-ACTX-Hv1|||ω-Atracotoxin-HV1
ω-Hexatoxin-Hv1a, a neurotoxin extracted from the venom of the spider Hadronyche versuta, inhibits voltage-gated calcium channels [1] [2].
价 格:¥电议型 号:T80160产 地:中国大陆