TN27552-Desoxy-4-epi-pulchellin2Desoxy4epipulchellin,inhibit,2 Desoxy 4 epi pulchellin,Inhibitor

2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows significant antiviral (H1N1 and H3N2) activities, it also displays significant antimycobacterial activity (IC50=7.6 uM).

价 格：￥电议型 号：TN2755产 地：中国大陆

TN1927Methyl Kakuol

Methyl Kakuol is an agonist of TRPA1 with an EC50 of 0.27 ?M and can be used in studies about acting as an active ingredient in MBST constituent Asiasari Radix.

价 格：￥电议型 号：TN1927产 地：中国大陆

T19337GBR 12783 dihydrochloride

GBR 12783 dihydrochloride is a specific, potent and selective dopamine uptake inhibitor. GBR 12783 dihydrochloride inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively.GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats.

价 格：￥电议型 号：T19337产 地：中国大陆

TP2158TRV-120027 TFATRV 120027 TFA,TRV120027 TFA

TRV-120027 TFA is an angiotensin II–mediated vasoconstriction inhibitor and increases cardiomyocyte contractility. TRV-120027 TFA is a β-arrestin-1-biased AT1R agonist engaging ?-arrestins while blocking G-protein signaling[1]. TRV-120027 TFA induces acute catecholamine secretion through cation channel subfamily C3 (TRPC3) coupling and promotes the formation of a macromolecular complex composed of AT1R–β-arrestin-1–TRPC3–PLCγ at the plasma membrane.

价 格：￥电议型 号：TP2158产 地：中国大陆

T60127Chlorantraniliprole

Chlorantraniliprole is an insecticide. Chlorantraniliprole potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ?300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).

价 格：￥电议型 号：T60127产 地：中国大陆

T62209HS-276

HS-276 is an orally active, potent and highly selective TAK1 inhibitor (Ki= 2.5 nM). HS-276 exhibits significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 exhibits research potential for rheumatoid arthritis (RA) research.

价 格：￥电议型 号：T62209产 地：中国大陆

T27221DVR-01

DVR-01 is an HBV capsid inhibitor and can be used in studies about the treatment of Hepatitis B virus (HBV) infection and related conditions.

价 格：￥电议型 号：T27221产 地：中国大陆

T11027DHODH-IN-4DHODHIN4,DHODH IN 4

DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 μM and 0.18 μM, respectively. DHODH-IN-4 has antimalarial activity.

价 格：￥电议型 号：T11027产 地：中国大陆

T6612NU6027inhibit,Ataxia telangiectasia mutated,Cyclin dependent kinase,ATM/ATR,NU 6027,cytotoxicity,NU6

NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-aminopurine-based inhibitors.

价 格：￥电议型 号：T6612产 地：中国大陆

T22114NESS 0327NESS 0327

NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.

价 格：￥电议型 号：T22114产 地：中国大陆

T9258AficamtenCK3773274,CK-3773274,cardiac,CK-274,Myosin,cardiomyopathy,Inhibitor,CK 3773274,CK 274,hyper

Aficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.

价 格：￥电议型 号：T9258产 地：中国大陆

T12871Talmapimodcytotoxicity,multiple,inhibit,tumor,SCIO 469,SCIO469,cells,Hsp27,Inhibitor,phosphorylation

Talmapimod is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.

价 格：￥电议型 号：T12871产 地：中国大陆

TMO2752Cytidine 5’-monophosphateEndogenous Metabolite,Cytidine 5’ monophosphate,inhibit,Cytidine 5’monophos

A constituent of nucleic acids. It was isolated from yeast nucleic acid.

价 格：￥电议型 号：TMO2752产 地：中国大陆

T27704K00135

K00135 is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics.

价 格：￥电议型 号：T27704产 地：中国大陆

T7927β-IononeApoptosis,inhibit,β-Ionone,β Ionone,βIonone,Inhibitor

β-lonone is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetables,with anti-proliferative, anti-metastatic

价 格：￥电议型 号：T7927产 地：中国大陆

TP2318pro-asp TFA(85227-98-1 free base)proasp TFA(85227981 free base),pro asp TFA(85227 98 1 free base)

Pro-asp TFA down-regulate skin inflammation in mouse skin

价 格：￥电议型 号：TP2318产 地：中国大陆

TMO27134(3H)-QuinazolinoneInhibitor,Bacterial,4(3H)-Quinazolinone,4(3H)Quinazolinone,inhibit,4(3H) Quinazol

Some 4-quinazolinone derivatives have antiplatelet activity.

价 格：￥电议型 号：TMO2713产 地：中国大陆

T6S2227SpinosinInhibitor,neuroprotective,Spinosin,inhibit,Aβ1-42

1. Spinosin ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. 2. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. 3. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher

价 格：￥电议型 号：T6S2227产 地：中国大陆

TWO2724N,N-Bis(2-hydroxyethyl)-p-phenylenediamiN,NBis(2hydroxyethyl)pphenylenediami,N,N Bis(2 hydroxyethyl)

价 格：￥电议型 号：TWO2724产 地：中国大陆

T6783BI-7273inhibit,Inhibitor,Epigenetic Reader Domain,BI7273,BI-7273,BI 7273

BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.

价 格：￥电议型 号：T6783产 地：中国大陆