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  • T38856Biotin-PEG3-propargyl;Biotin-PEG3-propargylBiotin-PEG3-propargyl;Biotin-PEG3-propargyl

    Biotin-PEG3-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T38856产 地:中国大陆

  • T38855Melanin probe-1;Melanin probe-1Melanin probe-1

    Melanin probe-1, an 18F-picolinamide-based PET probe, is utilized for PET imaging of malignant melanoma. It demonstrates remarkable tumor targeting efficacy, superior tumor imaging contrasts, favorable biodistribution profiles, and robust in vivo stability.

    价 格:¥电议型 号:T38855产 地:中国大陆

  • T38854sFTX-3.3;sFTX-3.3sFTX-3.3

    sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.

    价 格:¥电议型 号:T38854产 地:中国大陆

  • T38853Methyl-PEG3-Ald;Methyl-PEG3-AldMethyl-PEG3-Ald;Methyl-PEG3-Ald

    Methyl-PEG3-Ald is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T38853产 地:中国大陆

  • T38852LTRAP-6 amide acetate;化合物TRAP-6 amide acetateTRAP-6 amide acetate

    TRAP-6 amide acetate is a?PAR-1 thrombin receptor?agonist peptide[1].

    价 格:¥电议型 号:T38852L产 地:中国大陆

  • T38852TRAP-6 amide;TRAP-6 amideTRAP-6 amide

    TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide.

    价 格:¥电议型 号:T38852产 地:中国大陆

  • T38850AZD4721;AZD4721RIST4721|||AZD4721;RIST4721|||AZD4721

    AZD4721 (RIST4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 ( CXCR2 ). AZD4721 has the potential for the research of inflammatory disease.

    价 格:¥电议型 号:T38850产 地:中国大陆

  • T38849Idrevloride;IdrevlorideIdrevloride

    Idrevloride is a chemical compound (WO2016133967) known for its effective inhibition of epithelial sodium channels (ENaC). Its application extends to the research of various skin disorders.

    价 格:¥电议型 号:T38849产 地:中国大陆

  • T38848DMT-dI Phosphoramidite;DMT-dI PhosphoramiditeDMT-dI Phosphoramidite

    Phosphoramidite (a modified phosphoramidite monomer) is utilized in the synthesis of oligonucleotides.

    价 格:¥电议型 号:T38848产 地:中国大陆

  • T38847VevorisertibVevorisertibVevorisertib|||ARQ 751

    Vevorisertib (ARQ 751) is a highly effective oral compound that selectively inhibits pan-AKT serine/threonine kinases such as AKT1 (with an IC50 value of 0.55 nM), AKT2 (with an IC50 value of 0.81 nM), and AKT3 (with an IC50 value of 1.31 nM). This compound, either as a standalone treatment option or in combination with other anti-cancer agents, is ideally suited for conducting research on solid tumors characterized by PIK3CA/AKT/PTEN mutations[4].

    价 格:¥电议型 号:T38847产 地:中国大陆

  • T38846Vevorisertib trihydrochloride;化合物Vevorisertib trihydrochlorideARQ 751 trihydrochloride;ARQ 751 trihy

    Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is a selective and potent inhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3. Vevorisertib trihydrochloride is used in the study of hepatocellular carcinoma and advanced solid tumours.

    价 格:¥电议型 号:T38846产 地:中国大陆

  • T38845Dodecamethylpentasiloxane;十二甲基五硅氧烷Dodecamethylpentasiloxane

    Dodecamethylpentasiloxane can be used as a bed bug insecticide. Dodecamethylpentasiloxane is a component of siloxane and can be used as silicone oil.

    价 格:¥电议型 号:T38845产 地:中国大陆

  • T38844MK-8245 Trifluoroacetate;MK-8245 TrifluoroacetateMK-8245 Trifluoroacetate

    MK-8245 trifluoroacetate is a phenoxy piperidine isoxazole derivative functioning as a potent, liver-targeting stearoyl-CoA desaturase (SCD) inhibitor, demonstrating significant anti-diabetic and anti-dyslipidemic effects. It showcases high specificity and efficacy against SCD1 across various species, with IC50 values of 1 nM for human SCD1 and 3 nM for both rat and mouse SCD1. MK-8245´s mechanism includes a tetrazole acetic acid moiety that facilitates liver-targeting through OATPs recogn

    价 格:¥电议型 号:T38844产 地:中国大陆

  • T38843Enavogliflozin;化合物EnavogliflozinDWP-16001;DWP-16001

    Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.

    价 格:¥电议型 号:T38843产 地:中国大陆

  • T38842HA-100 hydrochloride;HA-100 hydrochlorideHA-100 hydrochloride

    HA-100 hydrochloride is a powerful protein kinase inhibitor, exhibiting IC50 values of 4 μM, 8 μM, 12 μM, and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC), and MLC-kinase, respectively. Additionally, HA-100 hydrochloride is utilized as a ROCK inhibitor.

    价 格:¥电议型 号:T38842产 地:中国大陆

  • T38841IRE1α kinase-IN-2;IRE1α kinase-IN-2IRE1α kinase-IN-2;IRE1α kinase-IN-2

    IRE1α kinase-IN-2 is a highly potent inhibitor of IRE1α kinase, demonstrating an EC50 of 0.82 μM. It effectively impedes IRE1α kinase autophosphorylation with an IC50 of 3.12 μM. Additionally, IRE1α kinase-IN-2 effectively inhibits the splicing of XBP1 mRNA in wild-type cell lines.

    价 格:¥电议型 号:T38841产 地:中国大陆

  • T38840Mivorilaner;MivorilanerMivorilaner

    Mivorilaner is an antineoplastic compound that has shown potential for application in veterinary medicine research (WO2012155676, Example 245).

    价 格:¥电议型 号:T38840产 地:中国大陆

  • T3884Neoandrographolide;新穿心莲内酯Neoandrographiside;Neoandrographiside|||新穿心莲内酯

    Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iNOS and COX-2 expression through inhibiting p38 MAPKs activation.Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIAP)-overexpressing Jurkat cells, a model for chemoresistance.

    价 格:¥电议型 号:T3884产 地:中国大陆

  • T38839MCXu00A028;MCX 28MCXu00A028

    MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.

    价 格:¥电议型 号:T38839产 地:中国大陆

  • T38838QS-21;QS-21Stimulon|||QS-21;Stimulon|||QS-21

    QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, QS-21 activates the NLRP3 inflammasome, leading to the release of cytokines IL-1β and IL-18, which are dependent on caspase-1.

    价 格:¥电议型 号:T38838产 地:中国大陆

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