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  • T4134LOTS514；化合物OTS514OTS514 HCl|||OTS514 Hydrochloride|||OTS-514|||OTS 514；OTS514 HCl|||OTS514 Hydrochlor

    OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell lines (IC50: 0.4 ~ 42.6 nM). Treatment with OTS514 suppressed forkhead box protein M1 (FOXM1) activity. OTS514 treatment reduced CD90-positive SCLC cells and showed a higher cytotoxic effect against lung sphere-derived CSC-like SCLC cells.

    价 格：￥电议型 号：T4134L产 地：中国大陆

  • T4123LYN-1604；化合物LYN1604LYN1604；LYN1604

    LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.

    价 格：￥电议型 号：T4123产 地：中国大陆

  • T41070LP-184；LP-184LP-184

    LP-184 (Compound 6), referred to as an acylfulvene analog, demonstrates the ability to inhibit tumor growth with noteworthy anti-cancer efficacy observed across multiple cell lines, including ovarian, colon, prostate, and pancreatic.

    价 格：￥电议型 号：T41070产 地：中国大陆

  • T40870Leukotriene E4；白三烯 E4LTE4；LTE4

    Leukotriene E4 (LTE4) (LTE4) is produced by the action of dipeptidyl peptidase on LTD4 and is a component of the Slow Reactive Substance of Anaphylaxis (SRS-A).LTE4 is present in plasma and urine and can be used to detect asthma.

    价 格：￥电议型 号：T40870产 地：中国大陆

  • T4074LGSK872 HCl（1346546-69-7 free base）；化合物GSK872 HClGSK2399872A；GSK2399872A

    GSK872 HCl（1346546-69-7 free base） (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).

    价 格：￥电议型 号：T4074L产 地：中国大陆

  • T39264LCyclotriazadisulfonamide hydrochloride；化合物 Cyclotriazadisulfonamide hydrochlorideCyclotriazadisulfon

    Cyclotriazadisulfonamide hydrochloride is a selective inhibitor of CD4-targeted HIV entry and inhibits the co-translational translocation of human CD4 into the ER lumen in a signal peptide-dependent way.

    价 格：￥电议型 号：T39264L产 地：中国大陆

  • T39214LLXE408 fumarate；化合物LXE408 fumarateLXE408 fumarate (1799330-15-6 Free base)；LXE408 fumarate (1799330-

    LXE408 fumarate is an orally active, non-competitive and kinetoplastid-selective?proteasome?inhibitor. LXE408 fumarate has an?IC50?of 0.04 μM for?L. donovani?proteasome and an?EC50?of 0.04 μM for?L. donovani. LXE408 fumarate has a low propensity to cross the blood brain barrier. LXE408 fumarate has the potential for visceral leishmaniasis (VL) research.

    价 格：￥电议型 号：T39214L产 地：中国大陆

  • T38794LLLO (91-99) acetate；化合物LLO (91-99) acetateLLO (91-99) acetate(137856-41-8 free base)；LLO (91-99) ace

    LLO (91-99) acetate is an exotoxin and a class I MHC-restricted T-cell epitopes of listeriolysin. LLO (91-99) acetate is essential for the induction of T-cell mediated immunity in vivo.

    价 格：￥电议型 号：T38794L产 地：中国大陆

  • T38682Lys-Nε-SPDB-DM4；Lys-Nε-SPDB-DM4Lys-Nε-SPDB-DM4；Lys-Nε-SPDB-DM4

    Lys-Nε-SPDB-DM4 is a drug-linker conjugate that combines the tubulin inhibitor DM4 with the linker Lys-Nε-SPDB, facilitating the creation of an antibody-drug conjugate (ADC).

    价 格：￥电议型 号：T38682产 地：中国大陆

  • T38290Leucomycin A4；Leucomycin A4Leucomycin A4；Leucomycin A4

    Leucomycin A4 is a macrolide antibiotic that has been found in S. kitasatoensis. It is active against a variety of bacteria, including S. aureus, B. subtilis, C. diphtheriae, N. gonorrhoeae, and H. influenzae (MICs = 0.15, 1.25, 0.15, 0.6, and 0.15 μg/ml, respectively).

    价 格：￥电议型 号：T38290产 地：中国大陆

  • T38129Leukotriene F4；Leukotriene F4LTF4；LTF4

    LTF4 is a cysteinyl-leukotriene produced in vitro, but not reported to date in vivo. It is formed by the incubation of LTE4 with γ-glutamyl transpeptidase and glutathione. LTF4 is a weak agonist in its ability to contract vascular smooth muscle. [1] The rank order of potency of the cysteinyl-leukotrienes to contract vascular smooth muscle is LTD4 > LTC4 > LTE4 >> LTF4. [1] [2]

    价 格：￥电议型 号：T38129产 地：中国大陆

  • T37504LCathepsin D and E FRET Substrate acetate；Cathepsin D and E FRET Substrate 醋酸Cathepsin D and E FRET S

    Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E but not for B, H, or L. Cathepsin D and E FRET Substrate acetate can be used in mechanistic studies on cathepsins D and E studies.

    价 格：￥电议型 号：T37504L产 地：中国大陆

  • T37460Lipoxin B4；Lipoxin B4Lipoxin B4；Lipoxin B4

    Lipoxin B4 (LXB4) is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15(S)-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.

    价 格：￥电议型 号：T37460产 地：中国大陆

  • T3694LTebanicline tosylate；化合物 T3694LTebanicline tosylate

    Tebanicline is a potent synthetic nicotinic (non-opioid) analgesic drug. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine. Like epibatidine, tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound. It acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.

    价 格：￥电议型 号：T3694L产 地：中国大陆

  • T36813Lu AE98134；Lu AE98134Lu AE98134

    Lu AE98134, an activator of voltage-gated sodium channels, acts as a partly selective Nav1.1 channels positive modulator. Lu AE98134 also increases the activity of Nav1.2 and Nav1.5 channels but not of Nav1.4, Nav1.6 and Nav1.7 channels. Lu AE98134 can be used to analyze pathophysiological functions of the Nav1.1 channel in various central nervous system diseases, including cognitive restoring in schizophrenia, et al[1].

    价 格：￥电议型 号：T36813产 地：中国大陆

  • T36624Lα-Hydroxyglutaric Acid Lithium；α-Hydroxyglutaric Acid锂盐α-Hydroxyglutaric Acid Lithium(2889-31-8 Free

    α-Hydroxyglutaric Acid Lithium, converted from glutamate in microorganisms and animals, is an inhibitor of α-ketoglutarate-dependent dioxygenase and 5-methylcytosine hydroxylase, and has an inhibitory effect on ATP synthase and mTOR signaling.

    价 格：￥电议型 号：T36624L产 地：中国大陆

  • T36404LPRLX-93936 HCL；化合物 PRLX-93936 hclPRLX-93936 hcl(903499-49-0 Free base)；PRLX-93936 hcl(903499-49-0 Fr

    PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.

    价 格：￥电议型 号：T36404L产 地：中国大陆

  • T36051Lipoxin A4；脂氧素 A4LXA4；脂氧素 A4|||LXA4

    Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 in inducing superoxide generation in human neutrophils at 0.1 μM.2 LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.[2],[3],[4] Analytical and biological comparisons of synth

    价 格：￥电议型 号：T36051产 地：中国大陆

  • T35834L(Sar?)-Angiotensin II acetate；化合物(Sar?)-Angiotensin II acetate(Sar?)-Angiotensin II acetate

    (Sar?)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with a Kd of 2.7 nM. It can stimulate protein synthesis and cell growth in embryonic chick myocytes.

    价 格：￥电议型 号：T35834L产 地：中国大陆

  • T3539Lu AF21934；化合物Lu AF21934Lu AF21934

    Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).

    价 格：￥电议型 号：T3539产 地：中国大陆

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