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T9955EX-A5758EX A5758,EXA5758
EX-A5758 is a novel putative small molecule nNOS-NOS1AP inhibitor, suppressing inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability.
价 格:¥电议型 号:T9955产 地:中国大陆
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TP1185LCys-TAT(47-57) acetate(583836-55-9 Free base)CysTAT(4757) acetate(583836559 Free base),Cys TAT(47 57
Cys-TAT(47-57) acetate is derived from the HIV-1 transactivating protein. Cys-TAT(47-57) acetate is an arginine rich peptide that can penetrate cells.
价 格:¥电议型 号:TP1185L产 地:中国大陆
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T12758Ro 25-6981Ro 256981,Ro 25 6981
Ro 25-6981 is a potent and selective activity-dependent NMDA receptors blocker containing the NR2B subunit with IC50s of 0.009 and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively. Ro 25-6981 can be used in studies about Parkinson´s disease.
价 格:¥电议型 号:T12758产 地:中国大陆
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TJO2758D-Glucuronic acid1700908,Endogenous Metabolite,D Glucuronic acid,DGlucuronic acid,D-Glucuronic acid,
Glucuronic Acid is a carboxylic acid with structural similarity to glucose with detoxifying activity. The xenobiotic metabolism of various substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids involves glucuronidation, a process in which water-soluble, excretable glucuronides of these substances are formed via glycosidic linkages to glucuronic acid. UDP-glucuronic acid, formed in the liver thr
价 格:¥电议型 号:TJO2758产 地:中国大陆
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T8858DTHIBdegradation,HSP27,Inhibitor,inhibit,HSP70,HSF1,HSP,DTHIB,HSP90,cancer,nuclear,anticancer,Heat s
DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.
价 格:¥电议型 号:T8858产 地:中国大陆
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TP1107LMas7 acetate(145854-59-7 free base)Mas7 acetate(145854 59 7 free base),Mas-7 acetate(145854-59-7 fre
Mas7 acetate, a structural analogue of mastoparan is a known activator of heterotrimeric Gi-proteins and its downstream effectors.
价 格:¥电议型 号:TP1107L产 地:中国大陆
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TQ0037Abrocitinibinhibit,Abrocitinib,Inhibitor,JAK,PF04965842,Janus kinase,PF 04965842
Abrocitinib (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).
价 格:¥电议型 号:TQ0037产 地:中国大陆
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T6581MethyclothiazideCarbonic Anhydrase,Methyclothiazide,?stroke,?heart attack,thiazide diuretics,Inhibit
Methyclothiazide is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease.
价 格:¥电议型 号:T6581产 地:中国大陆
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T6458CYC-116CYC116,inhibit,Inhibitor,CYC-116,CYC 116,Aurora Kinase
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 and SAPK2A. Phase 1.
价 格:¥电议型 号:T6458产 地:中国大陆
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T60073WAY-658650WAY 658650,WAY658650
WAY-658650 has antibacterial activity against Mycobacterium tuberculosis.
价 格:¥电议型 号:T60073产 地:中国大陆
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T8951JTP 0819958 - HOIPIN-1JTP 0819958 HOIPIN1,JTP 0819958 HOIPIN 1
JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM[1]. JTP-0819958 suppress LUBAC-mediated NF-kB activation in vitro[2].
价 格:¥电议型 号:T8951产 地:中国大陆
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T9582CLEFMAcancer,Inhibitor,CLEFMA,anti-metastatic,Apoptosis,antitumor,curcuminoid,anti-inflammatory,inhi
CLEFMA has anti-proliferative activity. CLEFMA inhibits tumor growth associated with NF-κB-regulated anti-inflammatory and anti-metastatic effects.
价 格:¥电议型 号:T9582产 地:中国大陆
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TN1584Dihydropalmatine
Dihydropalmatine is a natural product derived from the roots and stem barks of Berberis aristata.
价 格:¥电议型 号:TN1584产 地:中国大陆
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T6870L-685458Apoptosis,alzheimer’s disease,L 685458,inhibit,L685458,HES1,cancer,Inhibitor,Gamma secretase
L-685, 458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.
价 格:¥电议型 号:T6870产 地:中国大陆
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T21587Muraglitazar
Muraglitazar is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitro at human PPARα and PPARγ with EC50 of 320 nM and 110 nM respectively.
价 格:¥电议型 号:T21587产 地:中国大陆
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TP1930L1Spexin acetate(1370290-58-6 free base)Spexin acetate(1370290586 free base),Spexin acetate(1370290 58
Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Attenuates LH secretion in goldfish. Exhibits anxiolytic effects in vivo.
价 格:¥电议型 号:TP1930L1产 地:中国大陆
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T8589(±)-AmiflamineFLA 336,Inhibitor,(±)-Amiflamine,(±)Amiflamine,(±) Amiflamine,FLA-336,MAO,Monoamine Ox
Amiflamine is an inhibitor of reversible MAO-A.
价 格:¥电议型 号:T8589产 地:中国大陆
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T8857LJP-1586 HCl
LJP-1586 HCl, a highly selective inhibitor of vascular adhesion protein-1 (VAP-1), exhibits antiinflammation effect by reducing adhesion molecule expression and immune cell infiltration after intracerebral hemorrhage (ICH).
价 格:¥电议型 号:T8857产 地:中国大陆
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T6758AnisomycinAnisomycin,Bacterial,Inhibitor,JNK,DNA/RNA Synthesis,inhibit,Antibiotic,Apoptosis
Anisomycin is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
价 格:¥电议型 号:T6758产 地:中国大陆
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TP1458LArg-Gly-Glu-Ser acetate(93674-97-6 free base)ArgGlyGluSer acetate(93674976 free base),Arg Gly Glu Se
Arg-Gly-Glu-Ser acetate is a RGD related peptide that is a control for the RGDS activity of fibrinogen binding to activated platelets.
价 格:¥电议型 号:TP1458L产 地:中国大陆