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T76004Super-TDU TFA;化合物 Super-TDU TFASuper-TDU TFA
Super-TDU TFA, a specialized YAP antagonist, specifically inhibits the interaction between YAP and TEADs. This compound demonstrates tumor growth suppression in a gastric cancer mouse model [1].
价 格:¥电议型 号:T76004产 地:中国大陆
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T76003MSG606 TFA;化合物 MSG606 TFAMSG606 TFA
MSG606 TFA, a potent antagonist of the human MC1 receptor (IC50 = 17 nM), functions as a partial agonist at the human MC3 and MC5 receptors (EC50 values of 59 and 1300 nM, respectively). It demonstrates binding affinity for A375 melanoma cells in vitro and selectively reverses induced hyperalgesia in female mice without affecting male mice.
价 格:¥电议型 号:T76003产 地:中国大陆
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T76002Spexin TFA;化合物 Spexin TFASpexin TFA
Spexin TFA, a potent agonist for galanin receptor 2/3 (GAL2/GAL3) with EC50 values of 45.7 and 112.2 nM respectively, shows no significant activity towards galanin receptor 1. As an endogenous peptide promoting satiety, it reduces long chain fatty acid uptake by adipocytes and lowers food consumption in diet-induced obese mice and rats. Additionally, it moderates LH secretion in goldfish and demonstrates anxiolytic effects in vivo.
价 格:¥电议型 号:T76002产 地:中国大陆
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T76001Apraglutide TFA;化合物 Apraglutide TFAApraglutide TFA
Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide functioning as a long-acting GLP-2 analogue, promotes adaptation and linear growth of the intestine in neonatal piglet models of short bowel syndrome following complete ileum resection [1].
价 格:¥电议型 号:T76001产 地:中国大陆
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T76000Aurantimycin A;化合物 Aurantimycin AAurantimycin A
Aurantimycin A (Adipogen), a depsipeptide antibiotic, exhibits potent efficacy against Gram-positive bacteria and serves as a substrate for the LieAB transporter [1] [2].
价 格:¥电议型 号:T76000产 地:中国大陆
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T7600Fucoxanthin;藻褐素all-trans-Fucoxanthin;all-trans-Fucoxanthin
Fucoxanthin (all-trans-Fucoxanthin) is a carotenoid that occurs naturally in certain algae. It is found as an accessory pigment in the chloroplasts of brown algae and most other heterokonts, giving them a brown or olive-green color.It shows anti-obesity, anti-oxidant, anti-diabetic, anticancer and anti-inflammatory activities.
价 格:¥电议型 号:T7600产 地:中国大陆
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T75600Coronatine;化合物 CoronatineCoronatine
Coronatine is a plant growth regulator synthesized by Pseudomonas syringae, mimicking bioactive jasmonic acid conjugates or octadecanoid signal molecules in higher plants, which induces pathogenic symptoms. It enhances the virulence of Pseudomonas syringae by triggering a signaling cascade that suppresses salicylic acid accumulation, thereby promoting infection [1] [2] [3] [4].
价 格:¥电议型 号:T75600产 地:中国大陆
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T74600Keap1-Nrf2-IN-9;化合物 Keap1-Nrf2-IN-9Keap1-Nrf2-IN-9
Keap1-Nrf2-IN-9 (compound 11) is a potent inhibitor of the Keap1-Nrf2 protein?protein interaction (PPI) with an IC50 value of 0.575 ?M. It enhances the expression of Nrf2 target genes, including heme oxygenase 1 (Hmox1), glutathione S-transferase P (GstP), and glutamate-cysteine ligase catalytic (Gclc) and modulatory (Gclm) subunits. Notably, Keap1-Nrf2-IN-9 is not cytotoxic to ARPE19 cells [1].
价 格:¥电议型 号:T74600产 地:中国大陆
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T73600Cefaloglycin;化合物 CefaloglycinCefaloglycin
Cefaloglycin (Cephaloglycin), an orally active, nephrotoxic β-lactam cephalosporin antibiotic, exhibits antibacterial activity primarily against Gram-Positive cocci, excluding enterococci. It impairs mitochondrial substrate uptake and respiration, underscoring its toxicity [1] [2] [3].
价 格:¥电议型 号:T73600产 地:中国大陆
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T72462(2S,5S)-Censavudine;化合物 (2S,5S)-Censavudine(2S,5S)-OBP-601 ; (2S,5S)-BMS-986001|||(2S,5S)-BMS-98600
(2S,5S)-Censavudine ((2S,5S)-OBP-601), the (2S,5S)-enantiomer of Censavudine, is a nucleoside reverse transcriptase inhibitor and a potent HIV inhibitor.
价 格:¥电议型 号:T72462产 地:中国大陆
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T71985ID110460002;化合物 ID110460002ID110460002
ID110460002 is a novel μ,δ-Opioid Receptor Dual-Biased Agonist, Overcoming the Limitation of Prior Biased Agonist.
价 格:¥电议型 号:T71985产 地:中国大陆
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T71946ID110460003;化合物 ID110460003ID110460003
ID110460003 is a novel μ,δ-Opioid Receptor Dual-Biased Agonist, Overcoming the Limitation of Prior Biased Agonist.
价 格:¥电议型 号:T71946产 地:中国大陆
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T71600Benazoline oxalate salt;化合物 Benazoline oxalate saltBenazoline oxalate salt
Benazoline oxalate salt is a pharmacological active compound that inhibits casein kinase Iε (CKIε) or CKIδ phosphorylation of the PER2 protein.
价 格:¥电议型 号:T71600产 地:中国大陆
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T71438ID110460001;化合物 ID110460001ID110460001
ID110460001 is a novel μ,δ-Opioid Receptor Dual-Biased Agonist, Overcoming the Limitation of Prior Biased Agonist.
价 格:¥电议型 号:T71438产 地:中国大陆
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T71375FTI-2600;化合物 FTI-2600FTI-2600
FTI-2600 is a farnesyltransferase inhibitor.
价 格:¥电议型 号:T71375产 地:中国大陆
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T70600BRD-7880;化合物 BRD-7880BRD-7880
BRD-7880 is a potent and highly specific inhibitor of aurora kinases B and C.
价 格:¥电议型 号:T70600产 地:中国大陆
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T70349DJT06001;化合物 DJT06001DJT06001
DJT06001 is a selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding.
价 格:¥电议型 号:T70349产 地:中国大陆
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T70237HX-600;化合物 HX-600HX-600
HX-600 is a synthetic agonist for the RXR-Nurr1 heterodimer complex. HX-600 prevents ischemia-induced neuronal damage.
价 格:¥电议型 号:T70237产 地:中国大陆
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T69780VU6007477;化合物 VU6007477VU6007477
VU6007477 is a novel M1 PAM. VU6007477 resulted in good rat M1 PAM potency (EC50 = 230 nM, 93% ACh max), minimal M1 agonist activity (agonist EC50 > 10 μM), good CNS penetration (rat brain/plasma Kp = 0.28, Kp,uu = 0.32; mouse Kp = 0.16, Kp,uu = 0.18), and no cholinergic adverse events (AEs, e.g., seizures).
价 格:¥电议型 号:T69780产 地:中国大陆
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T69600Spermidine-d6;化合物 Spermidine-d6Spermidine-d6
Spermidine-d6 is intended for use as an internal standard for the quantification of spermidine by GC- or LC-MS. Spermidine is an endogenous polyamine. It is formed from putrescine by spermidine synthase. Spermidine (25 ?M) inhibits the activity of the human inward-rectifying potassium channel Kir2.3 in a patch-clamp assay. It induces autophagy in HeLa cells when used at a concentration of 100 ?M and increases the lifespan of D. melanogaster, yeast, and C. elegans. Spermidine (30 mM in the drinki
价 格:¥电议型 号:T69600产 地:中国大陆