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  • T62931Antiangiogenic agent 2;化合物 Antiangiogenic agent 2Antiangiogenic agent 2

    Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.

    价 格:¥电议型 号:T62931产 地:中国大陆

  • T62930GT-055;化合物 GT-055GT-055

    GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.

    价 格:¥电议型 号:T62930产 地:中国大陆

  • T6293Mycophenolate Mofetil;吗替麦考酚酯TM-MMF|||RS 61443;TM-MMF|||吗替麦考酚酯|||RS 61443

    Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).

    价 格:¥电议型 号:T6293产 地:中国大陆

  • T62929RLX-33;化合物RLX-33RLX-33

    RLX-33 is a potent and selective antagonist of relaxin family peptide 3 (RXFP3) that crosses the blood-brain barrier and also blocks relaxin 3-induced ERK1/2 phosphorylation. RLX-33 can block the increase in food intake induced by the RXFP3 selective agonist R3/I5 in rats.RLX-33 can be used to study the metabolic syndrome.

    价 格:¥电议型 号:T62929产 地:中国大陆

  • T62928XR8-69;化合物 XR8-69XR8-69

    XR8-69 is a SARS-CoV-2 PLpro inhibitor. XR8-69 has a low micromolar antiviral effect in SARS-CoV-2 infected human cells.

    价 格:¥电议型 号:T62928产 地:中国大陆

  • T62927HPK1-IN-22;化合物 HPK1-IN-22HPK1-IN-22

    HPK1-IN-22 (compound ZYF0033) is a haematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of less than 10 nM for MBP protein-based phosphorylation inhibition. HPK1-IN-22 reduces phosphorylation of SLP76 (serine 376) and promotes anti-cancer immune responses. HPK1-IN-22 inhibits tumor growth and increases intra-tumor infiltration of DCs, NK cells and CD107a+CD8+ T cells, but decreases infiltration of T cells, PD-1+CD8+ T cells, TIM-3+CD8+ T cells and LAG3+CD8+ T cells in a 4T-1 homozygo

    价 格:¥电议型 号:T62927产 地:中国大陆

  • T62926CDK7/12-IN-1;化合物 CDK7/12-IN-1CDK7/12-IN-1

    CDK7/12-IN-1 is a selective inhibitor of CDK7/12, acting on CDK7 (IC50: 3 nM) and CDK 12 (IC50: 277 nM). Inhibition of CDK7 and CDK12 is an effective inhibitor of tumour growth.

    价 格:¥电议型 号:T62926产 地:中国大陆

  • T62925FASN-IN-5;化合物 FASN-IN-5FASN-IN-5

    FASN-IN-5 (example 11) is a FASN inhibitor that can be used in studies of TH17 or CSF1-mediated diseases or disorders (e.g. cancer, immune disorders, obesity).

    价 格:¥电议型 号:T62925产 地:中国大陆

  • T62924Ifetroban sodium;化合物 Ifetroban sodiumIfetroban sodium

    Ifetroban (BMS-180291) sodium is an orally active thromboxane A2 (TXA2) or prostaglandin H2 (PGH2) receptor antagonist. It is used to study myocardial ischaemia, stroke, hypertension, thrombosis and cardiomyopathy.

    价 格:¥电议型 号:T62924产 地:中国大陆

  • T62923SOS1-IN-7;化合物 SOS1-IN-7SOS1-IN-7

    SOS1-IN-7 (compound 18-p1) is a potent inhibitor of SOS1 and acts on SOS1-G12D (IC50: 20 nM) and SOS1-G12V (IC50: 67 nM).

    价 格:¥电议型 号:T62923产 地:中国大陆

  • T62922Tubulin inhibitor 25;化合物 Tubulin inhibitor 25Tubulin inhibitor 25

    Tubulin inhibitor 25 is a potent inhibitor of tubulin (IC50: 0.98 μM) and significantly inhibits HT29 cells. tubulin inhibitor 25 inhibits cell migration and microtubule formation and contributes to anti-angiogenesis.

    价 格:¥电议型 号:T62922产 地:中国大陆

  • T62920HDAC-IN-38;化合物 HDAC-IN-38HDAC-IN-38

    HDAC-IN-38 is a potent inhibitor of HDAC. HDAC-IN-38 has similar micromolar inhibitory effects on HDAC1, 2, 3, 5, 6 and 8, and also increases histone acetylation levels (H3K14 or H4K5). HDAC-IN-38 increases cerebral blood flow (CBF), reduces cognitive impairment and improves hippocampal atrophy.

    价 格:¥电议型 号:T62920产 地:中国大陆

  • T62923-Deazaneplanocin A;3-去氮腺嘌呤A3-Deazaneplanocin A

    3-Deazaneplanocin A (DZNep) is an attractive epigenetic anticancer agent through the inhibition of the cellular enhancer of zeste homolog 2 (EZH2) protein.

    价 格:¥电议型 号:T6292产 地:中国大陆

  • T62919CDK9-IN-13;化合物 CDK9-IN-13CDK9-IN-13

    CDK9-IN-13 is a potent and selective CDK inhibitor (IC50<3 nM). CDK9-IN-13 has a very short half-life in rodents.

    价 格:¥电议型 号:T62919产 地:中国大陆

  • T62918GPR84 antagonist 3;化合物 GPR84 antagonist 3GPR84 antagonist 3

    GPR84 Antagonist 3 (compound 42), a potent inhibitor of the G-protein-coupled receptor 84 (GPR84), exhibits a pIC50 value of 8.28, indicating strong antagonistic activity by inhibiting GTPγS. Additionally, it possesses a favorable pharmacokinetic profile, suitable for further research and development [1].

    价 格:¥电议型 号:T62918产 地:中国大陆

  • T62917MIR002;化合物 MIR002MIR002

    MIR002 is a potent, orally active dual inhibitor of DNA polymerase α (POLA1) and HDAC 11 with significant in vivo antitumor activity. p53 acetylation, p21 activation, cell cycle arrest in G1/S phase, and apoptosis induction.

    价 格:¥电议型 号:T62917产 地:中国大陆

  • T62916GEM144;化合物 GEM144GEM144

    GEM144 is a potent, orally active dual inhibitor of DNA polymerase α (POLA1) and HDAC 11. GEM144 induces p53 acetylation, activates p21, blocks the cell cycle in G1/S phase and induces apoptosis.

    价 格:¥电议型 号:T62916产 地:中国大陆

  • T62915Dot1L-IN-7;化合物 Dot1L-IN-7Dot1L-IN-7

    Dot1L-IN-7 (compound 25) is a selective and potent inhibitor of telomere silencing 1-like protein (DOT1L) (IC50: 1.0 μM).Dot1L-IN-7 selectively kills MLL-AF9 and does not affect the growth of E2A-HLF cells.

    价 格:¥电议型 号:T62915产 地:中国大陆

  • T62914NSC 828467;化合物 NSC 828467NSC 828467

    NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).

    价 格:¥电议型 号:T62914产 地:中国大陆

  • T62913Piroxicam cinnamate;化合物 Piroxicam cinnamatePiroxicam cinnamate

    Piroxicam cinnamate (Cinnoxicam) is a cyclooxygenase (COX) inhibitor that exhibits anti-inflammatory effects. piroxicam cinnamate can be used to study inflammatory degenerative bone and joint diseases, rheumatic diseases and varicocele-related oligospermia.

    价 格:¥电议型 号:T62913产 地:中国大陆

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