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T64238Aβ1–42 aggregation inhibitor 1;化合物 Aβ1–42 aggregation inhibitor 1Aβ1–42 aggregation inhibitor 1
Aβ1-42 aggregation inhibitor 1 effectively inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), demonstrating IC50 values of 2.64 μM and 1.29 μM, respectively. At a concentration of 25 μM, it also reduces self-mediated Aβ1-42 aggregation by 51.29%, showcasing its potential for Alzheimer´s disease research [1].
价 格:¥电议型 号:T64238产 地:中国大陆
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T64237ASB14780;化合物 ASB14780ASB14780
ASB14780 is a 4-phenoxy derivative and an inhibitor of cytoplasmic phospholipase cPLA2α (IC50: 20 nM).
价 格:¥电议型 号:T64237产 地:中国大陆
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T64236AS 1411;化合物 AS 1411AS 1411
AS1411 is a nucleic acid aptamer that targets nucleophosmin and exhibits antitumour effects.
价 格:¥电议型 号:T64236产 地:中国大陆
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T64235Antifungal agent 25;化合物 Antifungal agent 25Antifungal agent 25
Antifungal agent 25 is an effective, broad-spectrum, metabolically stable antifungal agent in vivo. antifungal agent 25 exhibits antifungal effects against both Candida albicans and fluconazole-resistant Candida albicans.
价 格:¥电议型 号:T64235产 地:中国大陆
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T64233Alicaforsen;化合物 AlicaforsenAlicaforsen
Alicaforsen is a 20 base length antisense oligonucleotide that exhibits an inhibitory effect on ICAM-1 production. ICAM-1 is an important adhesion molecule that is involved in the migration and transport of leukocytes to sites of inflammation.
价 格:¥电议型 号:T64233产 地:中国大陆
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T64232Agatolimod;化合物 AgatolimodAgatolimod
Agatolimod (ODN 2006) is a TLR9 agonist, a class B ODN (oligodeoxynucleotide) and the optimal human CpG sequence (sequence: 5´-tcgtcgttttttgtcgttttgtcgtt-3´). agatolimod stimulates NO2 and IL-6 production in HD11 cells. Agatolimod can be used to study breast cancer.
价 格:¥电议型 号:T64232产 地:中国大陆
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T642313,6-DMAD hydrochloride;化合物 3,6-DMAD hydrochloride3,6-DMAD hydrochloride
3,6-DMAD hydrochloride is an inhibitor of the unfolded protein response (IRE1α-XBP1) pathway.
价 格:¥电议型 号:T64231产 地:中国大陆
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T64230α-Glucosidase-IN-3;化合物 α-Glucosidase-IN-3α-Glucosidase-IN-3
α-Glucosidase-IN-3 is an oleanolic acid oxime ester derivative targeting α-glucosidase and α-amylase with an IC50 value of 0.35 μM for α-glucosidase.
价 格:¥电议型 号:T64230产 地:中国大陆
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T6423BRL-15572 dihydrochloride;四氢罂粟碱盐酸盐BRL 15573 dihydrochloride;四氢罂粟碱盐酸盐|||BRL 15573 dihydrochloride
BRL-15572 dihydrochloride (BRL 15573 dihydrochloride) is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor.
价 格:¥电议型 号:T6423产 地:中国大陆
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T64229SENP2-IN-1;化合物 SENP2-IN-1SENP2-IN-1
SENP2-IN-1 is a selective inhibitor of SENP2. SENP2-IN-1 inhibits SENP1 (IC50: 1.3 μM), SENP2 (IC50: 0.69 μM) and SENP5 (IC50: 22.7 μM). SENP2-IN-1 can be used in cancer research.
价 格:¥电议型 号:T64229产 地:中国大陆
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T64228ALDH1A1-IN-3;化合物 ALDH1A1-IN-3ALDH1A1-IN-3
ALDH1A1-IN-3 is a good and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50: μM).ALDH1A1-IN-3 is effective in improving glucose consumption in HepG2 cells.ALDH1A1-IN-3 can be used for studies to improve glucose metabolism.
价 格:¥电议型 号:T64228产 地:中国大陆
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T64227JAK2 JH2 binder-1;化合物 JAK2 JH2 binder-1JAK2 JH2 binder-1
JAK2 JH2 binder-1 is a potent and selective JAK2 JH2 binder (Ki: 37.1 nM). JAK2 JH2 binder-1 has the potential to be used in the study of various myeloproliferative neoplasms.
价 格:¥电议型 号:T64227产 地:中国大陆
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T64226Tandutinib hydrochloride;化合物 Tandutinib hydrochlorideTandutinib hydrochloride
Tandutinib hydrochloride (MLN518 hydrochloride) is a potent, selective FLT3 inhibitor with an IC50 of 0.22 μM. It also effectively inhibits c-Kit and PDGFR, with IC50 values of 0.17 μM and 0.20 μM, respectively. This compound is clinically applicable for treating acute myelogenous leukemia (AML) and possesses the capability to cross the blood-brain barrier.
价 格:¥电议型 号:T64226产 地:中国大陆
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T64225Sacibertinib;化合物 SacibertinibSacibertinib
Sacibertinib is a tyrosine kinase (Trk) inhibitor that acts against EGFR-TK phosphorylation (EC50: 110 nM) and HER2 (EC50: 244 nM) and exhibits antitumour effects.
价 格:¥电议型 号:T64225产 地:中国大陆
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T64223RMS5;化合物 RMS5RMS5
RMS5 is a hambanine analogue and a potent P-glycoprotein (P-gp) inhibitor.RMS5 has significant anti-proliferative and cytotoxic effects on cancer cells.RMS5 slightly reduces the expression of the anti-apoptotic Bcl-2 family proteins Bcl-XL and Mcl-1.RMS3 causes cleavage of PARP, a marker of apoptosis.RMS5 has strong anti-cancer properties. RMS5 has strong anti-cancer properties.
价 格:¥电议型 号:T64223产 地:中国大陆
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T64222Antitumor agent-55;化合物 Antitumor agent-55Antitumor agent-55
Antitumor agent-55 (compound 5q) is a potent antitumour agent that effectively inhibits PC3 (IC50: 0.91 μM). antitumor agent-55 blocks the G1/S phase of the PC3 cell cycle, induces apoptosis, inhibits cell migration and prevents the formation of PC3.
价 格:¥电议型 号:T64222产 地:中国大陆
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T64221Linvencorvir;化合物LinvencorvirRG7907;RG7907
Linvencorvir is a hepatitis B virus (HBV) core protein variant modifier used to treat chronic HBV infection.
价 格:¥电议型 号:T64221产 地:中国大陆
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T64220Cyclophilin inhibitor 3;化合物 Cyclophilin inhibitor 3Cyclophilin inhibitor 3
Cyclophilin inhibitor 3 (compound 7c), a potent inhibitor of cyclophilin A (CypA), exhibited potent anti-HCV effects with an EC50 value of 4.2 μM.
价 格:¥电议型 号:T64220产 地:中国大陆
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T6422Brimonidine Tartrate;酒石酸溴莫尼定AGN190342 tartrate|||304 tartrate|||AGN190342 (tartrate)|||UK 14304 (tar
Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucoma or ocular hypertension.
价 格:¥电议型 号:T6422产 地:中国大陆
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T64219PI3K/mTOR Inhibitor-6;化合物 PI3K/mTOR Inhibitor-6PI3K/mTOR Inhibitor-6
PI3K/mTOR Inhibitor-6 (Compound 19c) is a potent dual PI3K/mTOR inhibitor that is more stable than gedatolisib in artificial gastric fluid. 10 μM of PI3K/mTOR Inhibitor-6 significantly inhibits the PI3K/Akt/mTOR signalling pathway. PI3K/mTOR Inhibitor-6 has shown potential for research in cancer diseases.
价 格:¥电议型 号:T64219产 地:中国大陆