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T76811Imgatuzumab;化合物 ImgatuzumabImgatuzumab
Imgatuzumab (RG 7160), a humanized monoclonal antibody targeting the epidermal growth factor receptor (EGFR), serves as an immunomodulator. It is utilized in cancer research [1].
价 格:¥电议型 号:T76811产 地:中国大陆
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T75811PBP10 TFA;化合物 PBP10 TFAPBP10 TFA
PBP10, a cell-permeable and selective gelsolin-derived peptide, inhibits formyl peptide receptor 2 (FPR2) over FPR1 [1]. This 10-amino acid (AA) peptide features a rhodamine conjugation at its N terminus, exhibiting bactericidal activity against both gram-positive and gram-negative bacteria while mitigating microbial-induced inflammatory effects [2].
价 格:¥电议型 号:T75811产 地:中国大陆
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T74811tau/Aβ40 aggregation-IN-1;化合物 tau/Aβ40 aggregation-IN-1tau/Aβ40 aggregation-IN-1
Tau/Aβ40 aggregation-IN-1 (Compound 20) functions as an inhibitor for tau and Aβ 40 aggregation, exhibiting IC50 values of 1.8 μM and 1.3 μM, respectively [1].
价 格:¥电议型 号:T74811产 地:中国大陆
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T73811AT-1002 TFA;化合物 AT-1002 TFAAT-1002 TFA
AT-1002 TFA, a 6-mer synthetic peptide, functions as a tight junction regulator and absorption enhancer.
价 格:¥电议型 号:T73811产 地:中国大陆
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T72811E7766 disodium;化合物 E7766 disodiumE7766 disodium
E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.
价 格:¥电议型 号:T72811产 地:中国大陆
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T71939PS77;化合物 PS77PS77|||PS-77|||SLR080811|||PS 77|||SLR 080811.;PS77|||PS-77|||SLR080811|||PS 77|||SLR 0
PS77 is a Pkh inhibitor directed to the PIF-pocket with increased selectivity for C. albicans Pkh2.
价 格:¥电议型 号:T71939产 地:中国大陆
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T71811Lobaric acid;化合物 Lobaric acidLobaric acid
Lobaric acid is a depsidone metabolite that has been isolated from Stereocaulon lichen species with antioxidant, antiproliferative, antiviral, and enzyme inhibitory activites. It scavenges superoxide radicals in a cell-free assay (IC50 = 97.9 μmol) and inhibits proliferation in a panel of leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic, and lung cancer cell lines (EC50s = 15.2-63.9 μg/ml). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50 = 0.87 μM for the h
价 格:¥电议型 号:T71811产 地:中国大陆
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T71162MDL-73811;化合物 MDL-73811MDL-73811
MDL-73811 is a potent AdoMetDC (S-adenosylmethionine decarboxylease) inhibitor and anti-trypanosomal compound that cures Brucella infections in mice. However despite the good activity of MDL 73811, rapid plasma clearance and poor brain penetration hindered its further development.
价 格:¥电议型 号:T71162产 地:中国大陆
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T70893K811;化合物 K811K811
K811 is an ASK1-specific inhibitor that prolongs survival in a mouse model of amyotrophic lateral sclerosis. K811 efficiently prevented cell proliferation in cell lines with high ASK1 expression and in HER2-overexpressing GC cells. Treatment with K811 reduced sizes of xenograft tumors by downregulating proliferation markers.
价 格:¥电议型 号:T70893产 地:中国大陆
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T70811CRV431;化合物 CRV431CRV431
CRV431 is a novel Pan-Cyclophilin Inhibitor, potently inhibiting all cyclophilin isoforms tested - A, B, D, and G (IC50 values ranged from 1-7 nM).
价 格:¥电议型 号:T70811产 地:中国大陆
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T70769Dmp 811;化合物 Dmp 811Dmp 811
Dmp 811 is an angiotensin II receptor antagonist.
价 格:¥电议型 号:T70769产 地:中国大陆
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T70614SLR080811 HCl;化合物 SLR080811 HClSLR080811 HCl
SLR080811 is a SphK inhibitor. Sphingosine-1-phosphate (S1P) is a ubiquitous, endogenous small molecule that is synthesized by two isoforms of sphingosine kinase (SphK1 and 2). Intervention of the S1P signaling pathway has attracted significant attention because alteration of S1P levels is linked to several disease states including cancer, fibrosis, and sickle cell disease.
价 格:¥电议型 号:T70614产 地:中国大陆
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T69811AGI25696;化合物 AGI25696AGI25696
AGI-25696 is a MATA2 inhibitor that are useful as therapeutic agents for treating malignancies. AGI-25696 showed in vivo activity in MTAP null tumors. Note: The correct structure of AGI-25696 is CAS#2201065-84-9. Many vendors mistakenly listed CAS#2201066-35-3 as its AGI25696. J. Med. Chem. 2021, 64, 8, 4430–4449 published AGI25696 structure (it is CAS#2201065-84-9).
价 格:¥电议型 号:T69811产 地:中国大陆
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T68811Trimetaphan camsilate;化合物 Trimetaphan camsilateTrimetaphan camsilate
Trimetaphan camsilate is a drug that counteracts cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathetic nervous system. It acts as a non-depolarizing competitive antagonist at the nicotinic acetylcholine receptor, is short-acting, and is given intravenously.
价 格:¥电议型 号:T68811产 地:中国大陆
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T68119Ontazolast;昂唑司特BIRM-270;BIRM-270
Ontazolast is a small molecule leukotriene B4 receptor (LTB4R) antagonist for the treatment of immune system disorders and respiratory diseases.Ontazolast is a candidate compound for the treatment of asthma.
价 格:¥电议型 号:T68119产 地:中国大陆
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T68118Nufenoxole;奴芬克索Nufenoxole
Nufenoxole is an orally active and antidiarrhoeal compound that inhibits fluid secretion in the human jejunum.
价 格:¥电议型 号:T68118产 地:中国大陆
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T68116L(Rac)-Norcisapride;化合物(Rac)-Norcisaprideide(Rac)-Norcisapride
Norcisapride is a 5-hydroxytryptamine receptor 3 (5-HT3) and (5-hydroxytryptamine receptor 4 (5-HT4) dual agonist used for the treatment of gastrointestinal disorders, orofacial disorders, and otorhinolaryngologic disorders.
价 格:¥电议型 号:T68116L产 地:中国大陆
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T68115Nicanartine;尼卡那汀Nicanartine
Nicanartine is a cholesterol inhibitor that is used to treat cardiovascular disease and can be used to study atherosclerosis.
价 格:¥电议型 号:T68115产 地:中国大陆
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T68114LNardeterol HCl;那地特罗盐酸盐Nardeterol HCl(73865-18-6 Free base);Nardeterol HCl(73865-18-6 Free base)
Nardeterol HCl is a β-adrenergic receptor partial agonist used in the study of the central nervous system.CAS ??13460-73-83-4
价 格:¥电议型 号:T68114L产 地:中国大陆
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T68114nardeterol;化合物 nardeterolnardeterol
Nardeterol is a high-affinity, partial agonist for beta adrenergic receptors.
价 格:¥电议型 号:T68114产 地:中国大陆