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T19253Cyclic ADP-?ribose;化合物 T19253cADPR;cADPR
Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger, which is synthesized from NAD + by ADP-ribosyl cyclase. Cyclic ADP-ribose mainly increases cytosolic calcium through Ryanodine receptor-mediated endoplasmic reticulum release and extracellular influx caused by the opening of TRPM2 channels.
价 格:¥电议型 号:T19253产 地:中国大陆
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T19251CTX-0294885 hydrochloride (1439934-41-4 free base);化合物 T19251CTX-0294885 hydrochloride;CTX-0294885 h
CTX-0294885 hydrochloride is an agarose-supported kinase capture reagent.
价 格:¥电议型 号:T19251产 地:中国大陆
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T19250cRIPGBM;化合物 T19250cRIPGBM
cRIPGBM, a proapoptotic derivative of RIPGBM, selectively induces apoptosis in GBM cancer stem cells (CSCs) by targeting receptor-interacting protein kinase 2 (RIPK2), demonstrating an EC50 of 68 nM in GBM-1 cells [1].
价 格:¥电议型 号:T19250产 地:中国大陆
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T1925PLX647;化合物PLX647PLX647
PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).
价 格:¥电议型 号:T1925产 地:中国大陆
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T1910925-Hydroxy VD2-D6;化合物 T1910925-Hydroxy VD2-D6
25-Hydroxy VD2-D6 is a labelled metabolite of Vitamin D2.
价 格:¥电议型 号:T19109产 地:中国大陆
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T18925Beryllon II铍试剂 II铍试剂II|||铍试剂 II
Beryllon II is a widely used chromogenic reagent that is used to determine proteins and many elements, such as Mg, Mo, and Co.
价 格:¥电议型 号:T18925产 地:中国大陆
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T17925(S,R,S)-AHPC-PEG2-NH2化合物(S,R,S)-AHPC-PEG2-NH2VH032-PEG2-NH2|||VHL Ligand-Linker Conjugates 3|||E3 li
(S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.
价 格:¥电议型 号:T17925产 地:中国大陆
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T16925SQ109;化合物SQ109NSC 722041;NSC 722041
SQ109 (NSC-722041) is an effective inhibitor of the trypomastigote form of the parasite (IC50 = 50 nM). SQ109 is an antitubercular agent and targets MmpL3.
价 格:¥电议型 号:T16925产 地:中国大陆
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T16352NSC23925;化合物 T16352NSC23925
NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).
价 格:¥电议型 号:T16352产 地:中国大陆
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T15925m-PEG7-NHS ester;化合物 T15925m-PEG7-NHS ester
m-PEG7-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15925产 地:中国大陆
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T14925Cenisertib;化合物 T14925AS-703569|||R-763;AS-703569|||R-763
Cenisertib is A potent ATP-competitive multi-kinase inhibitor, showing inhibitory effects on the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5, FLT3, as well as kinase inhibitors of FER and its homolog. Cenisertib inhibits the growth of tumor mast cells (MCS) by inhibiting the activity of several different molecular targets. Cenisertib also inhibits tumor growth in pancreatic, breast, colon, ovarian and lung cancer and leukemia in xenograft models.
价 格:¥电议型 号:T14925产 地:中国大陆
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T13925THS-044;化合物THS-044N-[2-Nitro-4-(Trifluoromethyl)phenyl]morpholin-4-Amine|||N-Morpholino-2-nitro-4-(t
THS-044 (N-[2-Nitro-4-(Trifluoromethyl)phenyl]morpholin-4-Amine) binding stabilizes the HIF2α PAS-B folded state with a kd of 2 μM and regulates HIF2 activity in endogenous and clinical settings.
价 格:¥电议型 号:T13925产 地:中国大陆
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T12925Sitravatinib malate;化合物 T12925MGCD516 malate|||MG-516 malate;MGCD516 malate|||MG-516 malate
Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively.) , shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment.
价 格:¥电议型 号:T12925产 地:中国大陆
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T125925Avocadenol D;化合物 Avocadenol DAvocadenol D
Avocadenol D is a useful organic compound for research related to life sciences. The catalog number is T125925 and the CAS number is 1401255-00-2.
价 格:¥电议型 号:T125925产 地:中国大陆
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T123925Antibiotic LL-D253alpha;化合物 Antibiotic LL-D253alphaAntibiotic LL-D253alpha
Antibiotic LL-D253alpha is a useful organic compound for research related to life sciences. The catalog number is T123925 and the CAS number is 92589-99-6.
价 格:¥电议型 号:T123925产 地:中国大陆
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T11925M?89;化合物M?89M?89
M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia.
价 格:¥电议型 号:T11925产 地:中国大陆
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T11719JMV 2959 hydrochloride (925238-89-7 free base);化合物JMV 2959 hydrochlorideJMV 2959 hydrochloride;JMV 2
JMV 2959 hydrochloride (925238-89-7 free base) is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.
价 格:¥电议型 号:T11719产 地:中国大陆
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T10925LCysteine Protease inhibitor hydrochloride;化合物 T10925LCysteine Protease inhibitor hydrochloride (9216
Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor.
价 格:¥电议型 号:T10925L产 地:中国大陆
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T10925Cysteine Protease inhibitor;半胱氨酸蛋白酶抑制剂Cysteine Protease inhibitor
Cysteine protease inhibitors are inhibitors of cysteine proteases. Target: Cysteine Protease
价 格:¥电议型 号:T10925产 地:中国大陆