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T196618-Chloroadenosine;8-氯腺嘌呤核苷NSC 354258|||8-Cl-Ado|||NSC354258|||NSC-354258;NSC 354258|||8-Cl-Ado|||NSC
8-Chloroadenosine (NSC-354258) is a 5´ AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia. 8-chloroadenosine activity is associated with inhibition of the mTOR pathway.8-Chloroadenosine (NSC-354258) is a nucleoside analog; metabolized in vivo to 8-Chloro-ATP. Incorporates into RNA during transcription and inhibits RNA synthesis. Exhibits cytotoxicity in MM.1S, RPMI-8226, and U266 cancer cell lines; induces G2/M cell cycle arrest and mitotic c
价 格:¥电议型 号:T19661产 地:中国大陆
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T19660QCC-374;化合物 T19660QCC374;QCC374
QCC-374 is a prostanoid agonist. It potentially for the treatment of pulmonary arterial hypertension.
价 格:¥电议型 号:T19660产 地:中国大陆
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T1966Tubastatin A;化合物Tubastatin ATubastatin A BASE;Tubastatin A BASE
Tubastatin A (Tubastatin A BASE) is an effective and specific HDAC6 inhibitor (IC50: 15 nM, in a cell-free assay). Its selectivity is 1000-fold against all the other isozymes except HDAC8.
价 格:¥电议型 号:T1966产 地:中国大陆
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T18966DAF-2DA;化合物 T18966DAF2DA|||DAF 2DA|||5,6-Diaminofluorescein diacetat;DAF2DA|||DAF 2DA|||5,6-Diaminof
DAF 2DA is widely used as a probe for NO measurement.
价 格:¥电议型 号:T18966产 地:中国大陆
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T17966Fmoc-NH-PEG11-CH2COOH;化合物 T17966Fmoc-NH-PEG11-CH2COOH
Fmoc-NH-PEG11-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17966产 地:中国大陆
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T1762RGFP966;化合物RGFP 966RGFP 966;RGFP 966
RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at concentrations up to 15 μM.
价 格:¥电议型 号:T1762产 地:中国大陆
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T16966S 3304;化合物S 3304S 3304
S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.
价 格:¥电议型 号:T16966产 地:中国大陆
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T16142MRT199665;化合物 T16142MRT199665
MRT199665 is an effective and ATP-competitive, selective MARK/SIK/AMPK inhibitor (IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively). MRT199665 suppresses the phosphorylation of SIK substrate CRTC3 at S370. MRT199665 induces apoptosis in MEF2C-activated human acute myeloid leukemia (AML) cells.
价 格:¥电议型 号:T16142产 地:中国大陆
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T15966Mal-amido-PEG9-NH-Boc;化合物 T15966Mal-amido-PEG9-NH-Boc
Mal-amido-PEG9-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15966产 地:中国大陆
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T15247ESI-05;化合物ESI-05NSC 116966;NSC 116966
ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.
价 格:¥电议型 号:T15247产 地:中国大陆
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T15142Vebufloxacin;化合物 T15142OPC7241|||Flumenique|||DM8966;OPC7241|||Flumenique|||DM8966
Vebufloxacin (OPC-7251) shows potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa. It has potent activity characteristically against Propionibacterium acnes.
价 格:¥电议型 号:T15142产 地:中国大陆
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T14966Cimetropium Bromide;西托溴铵DA-3177;西托溴铵|||DA-3177
Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.
价 格:¥电议型 号:T14966产 地:中国大陆
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T13966Wogonin 7-O-beta-D-glucuronide methyl ester;化合物 T13966Wogonoside methyl ester;Wogonoside methyl este
Wogonin 7-O-beta-D-glucuronide methyl ester is a natural product isolated from Huanglian Jiedutang.
价 格:¥电议型 号:T13966产 地:中国大陆
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T12966Sofosbuvir impurity K;索非布韦杂质 KSofosbuvir impurity K
Sofosbuvir impurity K is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
价 格:¥电议型 号:T12966产 地:中国大陆
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T12596612-O-Acetylrosmarinine;化合物 12-O-Acetylrosmarinine12-O-Acetylrosmarinine
12-O-Acetylrosmarinine is a useful organic compound for research related to life sciences and the catalog number is T125966.
价 格:¥电议型 号:T125966产 地:中国大陆
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T124966Tropanyl trans-cinnamate;化合物 Tropanyl trans-cinnamateTropanyl trans-cinnamate
Tropanyl trans-cinnamate is a useful organic compound for research related to life sciences and the catalog number is T124966.
价 格:¥电议型 号:T124966产 地:中国大陆
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T11966MCHR1 antagonist 2;化合物MCHR1 antagonist 2MCHR1 antagonist 2
MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.
价 格:¥电议型 号:T11966产 地:中国大陆
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T1185Rofecoxib;罗非考昔MK 966|||MK-0966;MK 966|||罗非昔布|||罗非考昔|||MK-0966
Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyretic and analgesic properties and potential antineoplastic properties. COX-related metabolic pathways may represent key regulators of cell proliferation and neo-angiogenesis. Some epithelial tumor cell types overexpress pro-angiogenic COX
价 格:¥电议型 号:T1185产 地:中国大陆
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T1174Topotecan hydrochloride;盐酸拓扑替康SKF 104864A|||SKFS 104864A|||NSC609699|||Nogitecan HCl|||NSC 609669|||
Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.
价 格:¥电议型 号:T1174产 地:中国大陆