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T16994Pimitespib;化合物TAS-116TAS-116;TAS-116
Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).
价 格:¥电议型 号:T16994产 地:中国大陆
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T15994Mal-PEG4-Val-Cit-PAB-OH;化合物 T15994Mal-PEG4-Val-Cit-PAB-OH
Mal-PEG4-Val-Cit-PAB-OH, a cleavable 4-unit PEG ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T15994产 地:中国大陆
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T15377Ravoxertinib hydrochloride化合物 T15377GDC-0994 (hydrochloride)
Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively).
价 格:¥电议型 号:T15377产 地:中国大陆
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T14994Coelenterazine h;腔肠素-H2-Deoxycoelenterazine|||CLZN-h;腔肠素-H|||2-Deoxycoelenterazine|||CLZN-h
Coelenterazine H is a synthetic derivative of coelenterazine (a light-emitting biomolecule).Coelenterazine h (CLZN-h) is more sensitive to Ca 2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca 2+ concentrations.
价 格:¥电议型 号:T14994产 地:中国大陆
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T14690BMS 433796;化合物BMS 433796BMS-289948|||BMS-299897;BMS-289948|||BMS-299897
BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer´s disease.
价 格:¥电议型 号:T14690产 地:中国大陆
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T14362LAY 9944 dihydrochloride;化合物AY 9944 盐酸盐AY 9944 dihydrochloride
AY 9944 dihydrochloride is a intermediate.
价 格:¥电议型 号:T14362L产 地:中国大陆
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T14362AY 9944;化合物AY 9944AY 9944
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol[1][2][3]. AY 9944 causes hypocholesterolemia and accumulation of 7DHC.
价 格:¥电议型 号:T14362产 地:中国大陆
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T139941-Isothiocyanato-PEG4-alcohol;化合物 T139941-Isothiocyanato-PEG4-alcohol
1-Isothiocyanato-PEG4-alcohol is a polyethylene glycol (PEG)-derived linker compound suitable for the incorporation into Proteolysis Targeting Chimeras (PROTACs)[1].
价 格:¥电议型 号:T13994产 地:中国大陆
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T12994SQ28603;化合物 T12994Squibb 28603|||SQ28,603;Squibb 28603|||SQ28,603
SQ28603 is a potent and selective neutral endopeptidase 3.4.24.11 (NEP) inhibitor.
价 格:¥电议型 号:T12994产 地:中国大陆
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T12898(+)-SHIN1;化合物 T12898(+)-RZ-2994;(+)-RZ-2994
(+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1 [1]. SHIN1 is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor.
价 格:¥电议型 号:T12898产 地:中国大陆
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T12897LSHIN1;化合物SHIN1RZ-2994;RZ-2994
SHIN1 (RZ-2994) is an inhibitor of human serine hydroxymethyltransferse 1(SHMT1) with IC50 of 5 nM and human serine hydroxymethyltransferse 2 (SHMT2) with an IC50 of 13 nM.
价 格:¥电议型 号:T12897L产 地:中国大陆
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T12897(-)-SHIN1;化合物 T12897(-)-RZ-2994;(-)-RZ-2994
(-)-SHIN1 ((-)-RZ-2994) is an inactive( ) enantiomer of SHIN1.
价 格:¥电议型 号:T12897产 地:中国大陆
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T1259943-Geranyl-4-hydroxy-5-prenylbenzoic acid;化合物 3-Geranyl-4-hydroxy-5-prenylbenzoic acid3-Geranyl-4-hyd
3-Geranyl-4-hydroxy-5-prenylbenzoic acid is a useful organic compound for research related to life sciences. The catalog number is T125994 and the CAS number is 135743-12-3.
价 格:¥电议型 号:T125994产 地:中国大陆
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T123994Gaudichaudic acid;化合物 Gaudichaudic acidGaudichaudic acid
Gaudichaudic acid is a useful organic compound for research related to life sciences and the catalog number is T123994.
价 格:¥电议型 号:T123994产 地:中国大陆
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T11994Melagatran;美拉加群Melagatran|||Melagatran;Melagatran|||Melagatran
Melagatran, a direct and orally active thrombin inhibitor, specifically inhibits thrombin without affecting other enzymes in the coagulation cascade or fibrinolytic enzymes. It does not rely on endogenous co-factors to exert its antithrombin effect, and may alleviate the harmful effects of endotoxemia. As a result, Melagatran offers a promising strategy for the prevention of arterial occlusion.
价 格:¥电议型 号:T11994产 地:中国大陆
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T11826LCH-7749944;化合物LCH-7749944GNF-PF-2356;GNF-PF-2356
LCH-7749944 (GNF-PF-2356) effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. LCH-7749944 is a potent PAK4 inhibitor with an IC50 of 14.93 μM.
价 格:¥电议型 号:T11826产 地:中国大陆
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T11521GW 766994;化合物 T11521GW 994;GW 994
GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.
价 格:¥电议型 号:T11521产 地:中国大陆
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T10994L2Deltasonamide 2 (TFA);化合物 T10994L2Deltasonamide 2 (TFA)
Deltasonamide 2 TFA is competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM.
价 格:¥电议型 号:T10994L2产 地:中国大陆
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T10994LDeltasonamide 2 hydrochloride;化合物 T10994LDeltasonamide 2 hydrochloride (2088485-34-9 free base);Delt
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.
价 格:¥电议型 号:T10994L产 地:中国大陆