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  • T6884Namodenoson；化合物2-Cl-IB-MECA2-Cl-IB-MECA|||CF-102；2-Cl-IB-MECA|||CF-102

    Namodenoson (2-Cl-IB-MECA) is an adenosine A3 receptor agonist.

    价 格：￥电议型 号：T6884产 地：中国大陆

  • T65979Adenosine 5’-monophosphate disodium salt；5‘-腺嘌呤核苷酸二钠盐Adenosine Phosphate Disodium|||5‘-AMP-NA2；Adeno

    Adenosine 5´-monophosphate disodium salt (Adenosine Phosphate Disodium) is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP on cells and organisms. Adenosine 5´-monophosphate disodium salt has been shown to have a variety of biochemical and physiological effects. It has been shown to increase cell metabolism, gene expression, and protein synthesis.

    价 格：￥电议型 号：T65979产 地：中国大陆

  • T65016Bleomycin A2；化合物 Bleomycin A2Bleomycin A2

    Bleomycin A2, a DNA-degrading antitumor antibiotic, functions as an inhibitor of aspartate/asparagine-β-hydroxylase (AspH), exhibiting an inhibitory concentration (IC 50) of 1.47 μM [1].

    价 格：￥电议型 号：T65016产 地：中国大陆

  • T63931Lp-PLA2-IN-9；化合物 Lp-PLA2-IN-9Lp-PLA2-IN-9

    Lp-PLA2-IN-9 (compound 17) is a tetracyclic pyrimidinone compound, a potent inhibitor of Lp-PLA2 that acts on rhLp-PLA2 (pIC50: 10.1). lp-PLA2-IN-9 has shown research potential in neurodegenerative diseases.

    价 格：￥电议型 号：T63931产 地：中国大陆

  • T63633Lp-PLA2-IN-6；化合物 Lp-PLA2-IN-6Lp-PLA2-IN-6

    Lp-PLA2-IN-6 is a tetracyclic pyrimidinone compound that is a potent inhibitor of Lp-PLA2 and is able to act on rhLp-PLA2 (pIC50: 10.0). lp-PLA2-IN-6 has shown research potential in neurodegenerative diseases.

    价 格：￥电议型 号：T63633产 地：中国大陆

  • T63400hA2A/hCA XII modulator 1；化合物 hA2A/hCA XII modulator 1hA2A/hCA XII modulator 1

    hA2A/hCA XII modulator 1 is a potent antagonist of the hA2A adenosine receptor (hA2AAR), a triazolopyrazine that acts on hA2AAR (Ki: 6.4 nM), hA1AR (Ki: 4.819 μM), and hA3AR (Ki>30 μM). hA2A/hCA XII modulator 1 Also a potent inhibitor of human carbonic anhydrase XII (hCA XII), capable of acting on hCA XII (Ki: 6.2 nM), hCA II (Ki: 46 nM), hCA IX (Ki: 466 nM) and hCA I (Ki: 8.351 μM). hA2A/hCA XII modulator 1 exhibits potential for cancer research.

    价 格：￥电议型 号：T63400产 地：中国大陆

  • T63373S100A2-p53-IN-1；化合物 S100A2-p53-IN-1S100A2-p53-IN-1

    S100A2-p53-IN-1 (compound 51), an inhibitor of S100A2-p53 interactions, targets S100A2, a Ca 2+ binding protein involved in cell signaling and commonly upregulated in pancreatic cancer. This compound effectively inhibits the growth of the MiaPaCa-2 pancreatic cancer cell line, showing a growth inhibition (GI 50) range of 1.2-3.4 μM [1].

    价 格：￥电议型 号：T63373产 地：中国大陆

  • T63345Lp-PLA2-IN-5；化合物 Lp-PLA2-IN-5Lp-PLA2-IN-5

    Lp-PLA2-IN-5 is a potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-5 has the potential to be studied in diseases associated with Lp-PLA2 activity, such as Alzheimer´s disease, atherosclerosis.Lp-PLA2-IN-5 is an inhibitor of platelet-activating factor acetylhydrolase (PAF-AH), a phospholipase A2 involved in lipoprotein lipid or phospholipid hydrolysis. Compound 35).

    价 格：￥电议型 号：T63345产 地：中国大陆

  • T63344Lp-PLA2-IN-4；化合物 Lp-PLA2-IN-4Lp-PLA2-IN-4

    Lp-PLA2-IN-4 is a potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-4 has the potential to be studied in diseases associated with Lp-PLA2 activity, such as Alzheimer´s disease, atherosclerosis, and is an inhibitor of platelet-activating factor acetylhydrolase (PAF-AH), a phospholipase A2 involved in lipoprotein lipid or phospholipid hydrolysis. Compound 38).

    价 格：￥电议型 号：T63344产 地：中国大陆

  • T63326A2A receptor antagonist 2；化合物 A2A receptor antagonist 2A2A receptor antagonist 2

    A2A receptor antagonist 2 is a highly selective and potent antagonist of the adenosine A2Areceptor (IC50: 8.3 nM).

    价 格：￥电议型 号：T63326产 地：中国大陆

  • T63192Lp-PLA2-IN-10；化合物 Lp-PLA2-IN-10Lp-PLA2-IN-10

    Lp-PLA2-IN-10 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), formerly known as platelet-activating factor acetylhydrolase (PAF-AH). This enzyme plays a role in the hydrolysis of lipoprotein lipids or phospholipids. The compound holds research potential for neurodegenerative diseases such as Alzheimer´s disease (AD), as well as glaucoma, age-related macular degeneration (AMD), and cardiovascular diseases like atherosclerosis[1].

    价 格：￥电议型 号：T63192产 地：中国大陆

  • T62977MA242 free base；化合物 MA242 free baseMA242 free base

    MA242 free base is a specific dual inhibitor of MDM2 and NFAT1 that induces apoptosis in pancreatic cancer cell lines. MA242 free base binds directly to MDM2 and NFAT1 with high affinity, induces MDM2 and NFAT1 protein degradation and inhibits NFAT1-mediated MDM2 transcription.

    价 格：￥电议型 号：T62977产 地：中国大陆

  • T62947Lp-PLA2-IN-11；化合物 Lp-PLA2-IN-11Lp-PLA2-IN-11

    Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2-IN-11 has the potential to be investigated in diseases associated with Lp-PLA2 activity (e.g. atherosclerosis, Alzheimer´s disease).

    价 格：￥电议型 号：T62947产 地：中国大陆

  • T62797A2A receptor antagonist 3；化合物 A2A receptor antagonist 3A2A receptor antagonist 3

    A2A receptor antagonist 3 (Example 92) is an adenosine A2a receptor antagonist (Ki: 0.4 nM). receptor (Ki: 1467 nM).

    价 格：￥电议型 号：T62797产 地：中国大陆

  • T62717A2AAR/HDAC-IN-2；化合物 A2AAR/HDAC-IN-2A2AAR/HDAC-IN-2

    A2AAR/HDAC-IN-2 is a potent dual A2AAR/HDAC inhibitor.A2AAR/HDAC-IN-2 shows good affinity for A2AAR (Ki:10.3 nM) and inhibits HDAC1 well (IC50:18.5 nM). A2AAR/HDAC-IN-2 can be used in anti-tumour studies.

    价 格：￥电议型 号：T62717产 地：中国大陆

  • T62521A2AAR/HDAC-IN-1；化合物 A2AAR/HDAC-IN-1A2AAR/HDAC-IN-1

    A2AAR/HDAC-IN-1 (compound 14c) is an orally active, balanced A2AAR/HDAC dual inhibitor of A2AAR (Ki: 163.5 nM), HDAC1 (IC50: 145.3 nM). effect.

    价 格：￥电议型 号：T62521产 地：中国大陆

  • T61322KA2507 monohydrochloride；化合物 KA2507 monohydrochlorideKA2507 monohydrochloride

    KA2507 hydrochloride is a powerful and specific HDAC6 inhibitor, possessing an IC50 value of 2.5 nM. It displays no substantial toxicities while demonstrating significant antitumor efficacy and immune modulatory effects [1].

    价 格：￥电议型 号：T61322产 地：中国大陆

  • T61266CA224；化合物 CA224CA224

    CA224 (Compound 1), an orally active and selective Cdk4–cyclin D1 inhibitor, demonstrates an IC50 of 6.2 ?M. It induces cell apoptosis and exhibits antitumor activity [1].

    价 格：￥电议型 号：T61266产 地：中国大陆

  • T60986KCa2 channel modulator 2；化合物 KCa2 channel modulator 2KCa2 channel modulator 2

    KCa2 channel modulator 2 (compound 2q) is an effective subtype-selective K/Ca 2 channel positive modulator which shows similar potency on the human K Ca 2.3 channel and rat K Ca 2.2a subtypes, with EC50 values of 0.60 μM and 0.64 μM, respectively [1].

    价 格：￥电议型 号：T60986产 地：中国大陆

  • T60985KCa2 channel modulator 1；化合物 KCa2 channel modulator 1KCa2 channel modulator 1

    KCa2 channel modulator 1 (compound 2o) is an effective subtype-selective K/Ca2 channel positive modulator that potentiates rat K Ca 2.2 channel subtype with an EC 50 value of 0.99 μM and human K Ca 2.3 channels subtype with an EC 50 value of 0.19 μM [1].

    价 格：￥电议型 号：T60985产 地：中国大陆

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