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T83779EP4 Antagonist 14;化合物 EP4 Antagonist 14Prostaglandin E2 Receptor 4 Antagonist 14|||PGE2 Receptor 4 A
EP4 antagonist 14 is a prostaglandin E2 receptor subtype EP4 antagonist, demonstrating an IC50 of 1.1 nM in a HEK293 human receptor reporter assay and blocking β-arrestin recruitment due to PGE2 with an IC50 of 0.9 nM. At 10 ?M, it reduces PGE2-stimulated mRNA levels of Il-4, macrophage mannose receptor 1 (Mrc1), chitinase-like protein 3 (Chil3), chemokine (C-X-C) motif ligand 1 (Cxcl1), triggering receptor expressed on myeloid cells 2 (Trem2), and arginase-1 (Arg1) in RAW 264.7 macrophages. Whe
价 格:¥电议型 号:T83779产 地:中国大陆
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T83773Prostaglandin E2 Inhibitor 3;化合物 Prostaglandin E2 Inhibitor 3PGE2 Inhibitor 3;PGE2 Inhibitor 3
Prostaglandin E2 (PGE2) inhibitor 3 is a selective inhibitor targeting microsomal prostaglandin E synthase-1 (mPGES-1; IC50 = 0.2 ?M), demonstrating greater selectivity for mPGES-1 over COX-1, COX-2, 5-lipoxygenase (5-LO), and soluble epoxide hydrolase (sEH) in assays at 10 ?M. This compound effectively reduces IL-1β-induced PGE2 production in A549 cells and decreases LPS-induced IL-6 and PGE2 in J774A.1 macrophages at concentrations of 10 and 1 ?M, respectively. Additionally, it blocks the prod
价 格:¥电议型 号:T83773产 地:中国大陆
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T83499[D-Phe2,6, Pro3]-LH-RH;化合物 [D-Phe2,6, Pro3]-LH-RH[D-Phe2,6, Pro3]-LH-RH
[D-Phe2,6, Pro3]-LH-RH is a potent antagonist of luteinizing hormone-releasing hormone (LHRH).
价 格:¥电议型 号:T83499产 地:中国大陆
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T83498[D-Phe2,D-Ala6]-LH-RH;化合物 [D-Phe2,D-Ala6]-LH-RHWy 18185;Wy 18185
[D-Phe2,D-Ala6]-LH-RH is a potent luteinizing hormone-releasing hormone (LH-RH) antagonist with demonstrated activities against LH/FSH-RH and an ability to inhibit ovulation [1].
价 格:¥电议型 号:T83498产 地:中国大陆
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T834122,3,4,6,7-Pentamethoxy-9,10-dihydrophenanthrene;化合物 2,3,4,6,7-Pentamethoxy-9,10-dihydrophenanthrene2
2,3,4,6,7-Pentamethoxy-9,10-dihydrophenanthrene, an active compound, can be isolated from Bulbophyllum vaginatum [1].
价 格:¥电议型 号:T83412产 地:中国大陆
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T834112,3,4,6,8-Pentahydroxy-1-methylxanthone;化合物 2,3,4,6,8-Pentahydroxy-1-methylxanthone2,3,4,6,8-Pentahy
2,3,4,6,8-Pentahydroxy-1-methylxanthone, a xanthone derivative of Wardomyces anomalus, exhibits significant antioxidant activities and functions as an inhibitor of the p56 lck tyrosine kinase. It has potential applications in the treatment of cardiovascular disease [1].
价 格:¥电议型 号:T83411产 地:中国大陆
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T834102,3,5,6-Tetramethoxyaporphine;化合物 2,3,5,6-Tetramethoxyaporphine2,3,5,6-Tetramethoxyaporphine
2,3,5,6-Tetramethoxyaporphine, a benzyl isoquinoline alkaloid with antitussive properties, can be extracted from Glaucium flavum Cr. (Family Papaveraceae) [1] [2].
价 格:¥电议型 号:T83410产 地:中国大陆
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T834092,3-Diaminophenazine;化合物 2,3-Diaminophenazine2,3-Phenazinediamine;2,3-Phenazinediamine
2,3-Diaminophenazine, also known as 2,3-Phenazinediamine, is a phenazine derivative characterized by amino groups that exhibits notable luminescent, electrochemical, and biochemical properties with potential applications in various fields [1] [2].
价 格:¥电议型 号:T83409产 地:中国大陆
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T834042,5-Dihydroxy-4-methoxyacetophenone;化合物 2,5-Dihydroxy-4-methoxyacetophenone2,5-Dihydroxy-4-methoxyac
Compound 3, 2,5-Dihydroxy-4-methoxyacetophenone, is isolated from the 80% methanol extract of the roots of Cynanchum paniculatum Kitagawa and has been shown to inhibit glutamate-induced cytotoxicity in the hippocampal HT22 cell line [1].
价 格:¥电议型 号:T83404产 地:中国大陆
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T834032,7-Bis(alloxycarbonylamino)-9-chloroacridine;化合物 2,7-Bis(alloxycarbonylamino)-9-chloroacridine2,7-B
2,7-Bis(alloxycarbonylamino)-9-chloroacridine serves as a fluorescent label.
价 格:¥电议型 号:T83403产 地:中国大陆
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T8339723-Epi-26-deoxycimicifugoside;化合物 23-Epi-26-deoxycimicifugoside23-Epi-26-deoxycimicifugoside
23-Epi-26-deoxycimicifugoside is a triterpene xyloside isolated from Cimicifuga racemosa [1].
价 格:¥电议型 号:T83397产 地:中国大陆
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T833892-Deoxy-D-galactose;化合物 2-Deoxy-D-galactose2-Deoxy-D-galactose
2-Deoxy-D-galactose, a glucose analog, impedes glycolysis, thereby inhibiting tumor growth, and interferes with fucosylation of glycomacromolecules, which impairs memory consolidation in learning tasks. Additionally, this compound hinders the fucosylation of glycoproteins in vivo [1].
价 格:¥电议型 号:T83389产 地:中国大陆
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T833882-Desoxyflorilenalin-L-α-arabinopyranoside;化合物 2-Desoxyflorilenalin-L-α-arabinopyranoside2-Desoxyflo
2-Desoxyflorilenalin-L-α-arabinopyranoside, an active compound, can be isolated from Helenium amarum [1].
价 格:¥电议型 号:T83388产 地:中国大陆
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T833872-Desoxypleniradin-4-0-a-L-rhamnopyranoside;化合物 2-Desoxypleniradin-4-0-a-L-rhamnopyranoside2-Desoxyp
2-Desoxypleniradin-4-O-α-L-rhamnopyranoside, a flavonoid, can be isolated from Helenium radiatum [1].
价 格:¥电议型 号:T83387产 地:中国大陆
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T833842-Hydroxy-1,3,4-trimethoxyanthraquinone;化合物 2-Hydroxy-1,3,4-trimethoxyanthraquinone2-Hydroxy-1,3,4-t
2-Hydroxy-1,3,4-trimethoxyanthraquinone is an anthraquinone derivative isolated from Cinchona ledgeriana [1].
价 格:¥电议型 号:T83384产 地:中国大陆
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T833832-Hydroxy4,7-dimethoxy-9,10-dihydrophenanthrene;化合物 2-Hydroxy4,7-dimethoxy-9,10-dihydrophenanthrene2
2-Hydroxy-4,7-dimethoxy-9,10-dihydrophenanthrene, isolated from the stem of Dendrobium nobile [1], is a natural product.
价 格:¥电议型 号:T83383产 地:中国大陆
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T833782-Methoxy-6-pentadecyl-1,4-benzoquinone;化合物 2-Methoxy-6-pentadecyl-1,4-benzoquinone2-Methoxy-6-penta
2-Methoxy-6-pentadecyl-1,4-benzoquinone (1c), a pentadecyl derivative, is isolatable from seed oils of various Iris species, including I. pseudacorus, I. missouriensis, and I. sibirica [1].
价 格:¥电议型 号:T83378产 地:中国大陆
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T833752-Phenethyl β-primeveroside;化合物 2-Phenethyl β-primeveroside2-Phenethyl β-primeveroside
2-Phenethyl β-primeveroside, a phenolic glycoside, can be isolated from Callianthemum taipaicum [1].
价 格:¥电议型 号:T83375产 地:中国大陆
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T83195Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27);化合物 Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-
Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP(1-7)-GRF(8-27) is a selective antagonist [1] for the vasoactive intestinal peptide 1 (VIP 1) receptor.
价 格:¥电议型 号:T83195产 地:中国大陆
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T81127Sophorose;化合物 Sophorose2-O-beta-D-Glucopyranosyl-D-glucopyranose;2-O-beta-D-Glucopyranosyl-D-glucopy
Sophorose, a disaccharide within sophorolipids synthesized by yeast, functions as a biosurfactant owing to its hydrophobic properties. It demonstrates multifaceted biological activities, including antibacterial, antifungal, spermicidal, virucidal, and anticancer effects. Furthermore, sophorose serves as a potent inducer of cellulase gene expression in Trichoderma reesei during fermentation.
价 格:¥电议型 号:T81127产 地:中国大陆