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  • T76556MEK1 Derived Peptide Inhibitor 1；化合物 MEK1 Derived Peptide Inhibitor 1MEK1 Derived Peptide Inhibitor

    MEK1 Derived Peptide Inhibitor 1, a peptide inhibitor, prevents the in vitro activation of ERK2 by MEK1, exhibiting an inhibitory concentration (IC 50) of 30 μM. It is utilized in the study of cell-permeable [1].

    价 格：￥电议型 号：T76556产 地：中国大陆

  • T75812MMK1 TFA；化合物 MMK1 TFAMMK1 TFA

    MMK1 TFA is a potent, selective agonist for the human formyl peptide receptor like-1 (FPRL-1/FPR2), exhibiting EC50 values of <2 nM for FPRL-1 and >10,000 nM for FPR1. This compound acts as a powerful chemotactic and calcium-mobilizing agent, effectively activating phagocytic leukocytes. It significantly enhances the Pertussis Toxin-sensitive production of proinflammatory cytokines IL-1b and IL-6 by human monocytes. Additionally, MMK1 TFA has been demonstrated to exhibit anxiolytic-like activity

    价 格：￥电议型 号：T75812产 地：中国大陆

  • T75435cis-Vitamin K1；化合物 cis-Vitamin K1cis-Vitamin K1

    Cis-Vitamin K1 is an endogenous metabolite of Vitamin K [1] .

    价 格：￥电议型 号：T75435产 地：中国大陆

  • T75182GK13S；化合物 GK13SGK13S

    G13KS is a deubiquitinase UCHL1 ligand and inhibitor. G13KS inhibits recombinant and cellular UCHL1. G13KS reduces levels of monoubiquitin in human glioblastoma cells [1] .

    价 格：￥电议型 号：T75182产 地：中国大陆

  • T74998LmNADK1-IN-1；化合物 LmNADK1-IN-1LmNADK1-IN-1

    LmNADK1-IN-1 (compound MC1) is an inhibitor of nicotinamide adenine dinucleotide kinases ( NADK1 ) from L. monocytogenes with a K i value of 54 nM. LmNADK1-IN-1 can be used for the research of bacterial infection [1] .

    价 格：￥电议型 号：T74998产 地：中国大陆

  • T74814PKM2/PDK1-IN-1；化合物 PKM2/PDK1-IN-1PKM2/PDK1-IN-1

    PKM2/PDK1-IN-1, a shikonin thioether derivative, serves as a dual inhibitor for PKM2/PDK1. This compound effectively inhibits the proliferation and induces apoptosis in NSCLC cells. It promotes intercellular ROS production and modulates apoptotic proteins, engaging in both mitochondrial and death receptor pathways [1].

    价 格：￥电议型 号：T74814产 地：中国大陆

  • T74777PLK1-IN-6；化合物 PLK1-IN-6PLK1-IN-6

    PLK1-IN-6, a potent and selective inhibitor of PLK1, demonstrates significant anti-proliferative activities against cancer cells with an IC50 value of 0.45 nM [1].

    价 格：￥电议型 号：T74777产 地：中国大陆

  • T74374ERK1/2 inhibitor 4；化合物 ERK1/2 inhibitor 4ERK1/2 inhibitor 4

    ERK1/2 Inhibitor 5, a potent suppressant of the ERK1/2 pathway, is instrumental in the mitogen-activated protein kinase (MAPK) signal transduction pathway, where extracellular signal-regulated kinase (ERK) serves as a critical component of the MAPK family. This compound holds promise for the investigation or mitigation of cancer, inflammation, or various proliferative diseases[1].

    价 格：￥电议型 号：T74374产 地：中国大陆

  • T74373ERK1/2 inhibitor 3；化合物 ERK1/2 inhibitor 3ERK1/2 inhibitor 3

    ERK1/2 Inhibitor 3, a potent inhibitor of ERK1/2, plays a crucial role in the signal transduction pathway by targeting the Mitogen-activated protein kinase (MAPK) family, specifically the extracellular signal-regulated kinase (ERK). Given its significant impact, this compound holds promise for research or prevention efforts related to cancer, inflammation, or other proliferative diseases[1].

    价 格：￥电议型 号：T74373产 地：中国大陆

  • T7392Revefenacin；化合物RevefenacinTD-4208|||GSK1160724；TD-4208|||GSK1160724

    Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.

    价 格：￥电议型 号：T7392产 地：中国大陆

  • T73322TBK1-IN-1；TBK1 抑制剂 1TBK1-IN-1

    TBK1-IN-1 is a specific and potent TANK-binding kinase 1 (TBK1) inhibitor (IC50: 22.4 nM) with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.

    价 格：￥电议型 号：T73322产 地：中国大陆

  • T73321CLK1-IN-2；化合物 CLK1-IN-2CLK1-IN-2

    CLK1-IN-2, a metabolically stable Clk1 inhibitor, exhibits selective activity for Clk1 with an IC50 value of 1.7 nM. It is applicable in researching tumor, Duchenne´s muscular dystrophy, and viral infections including HIV-1 and influenza.

    价 格：￥电议型 号：T73321产 地：中国大陆

  • T73295WNK1-IN-1；化合物 WNK1-IN-1WNK1-IN-1

    WNK1-IN-1, a selective inhibitor of WNK1, exhibits an IC50 value of 1.6 μM and also inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM, indicating its potential utility in the research of blood pressure regulation and cancer.

    价 格：￥电议型 号：T73295产 地：中国大陆

  • T73271MMV688845；化合物 MMV688845(R)-GSK1729177A；(R)-GSK1729177A

    MMV688845 is a bactericidal nontuberculous mycobacteria (NTM) RNA polymerase inhibitor that exhibits anti-tuberculosis efficacy and is effective against Mycobacterium abscessus.

    价 格：￥电议型 号：T73271产 地：中国大陆

  • T73186HPK1-IN-31；化合物 HPK1-IN-31HPK1-IN-31

    HPK1-IN-31 inhibitor with an IC 50 value of 0.8 nM. HPK1-IN-31 has anti-tumour activity and has great potential for immunotherapy [1] .

    价 格：￥电议型 号：T73186产 地：中国大陆

  • T73149HPK1-IN-33；化合物 HPK1-IN-33HPK1-IN-33

    HPK1-IN-33 (compound 21), a Hematopoietic Progenitor Kinase 1 (HPK1) inhibitor, exhibits a high potency with a K_i of 1.7 nM. It effectively inhibits IL-2 production, demonstrating EC_50 values of 286 nM in Jurkat WT cells and >10000 nM in Jurkat HPK1 KO cells [1].

    价 格：￥电议型 号：T73149产 地：中国大陆

  • T73141GSK1790627；化合物 GSK1790627GSK1790627

    GSK1790627, the N-deacetylated metabolite of Trametinib, represents an orally active MEK inhibitor that promotes autophagy and triggers apoptosis [1].

    价 格：￥电议型 号：T73141产 地：中国大陆

  • T72957DRAK1/2-IN-1；化合物 DRAK1/2-IN-1DRAK1/2-IN-1

    DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 ?M and 6 ?M, respectively.

    价 格：￥电议型 号：T72957产 地：中国大陆

  • T72808(R)-TTBK1-IN-1；化合物 (R)-TTBK1-IN-1(R)-TTBK1-IN-1

    (R)-TTBK1-IN-1 is a potent, selective, and brain-penetrant inhibitor of tau tubulin kinase 1 (TTBK1), serving as an enantiomer of TTBK1-IN-1. It finds application in the research of Alzheimer’s disease and related tauopathies [1].

    价 格：￥电议型 号：T72808产 地：中国大陆

  • T72421LRRK2/NUAK1/TYK2-IN-1；化合物 LRRK2/NUAK1/TYK2-IN-1LRRK2/NUAK1/TYK2-IN-1

    LRRK2/NUAK1/TYK2-IN-1 (compound 226) exhibits inhibitory activity against LRRK2 (Wt), LRRK2 (G2019), TYK2, and NUAK1, demonstrating IC50 values below 10 nM. This compound is useful for research into autoimmune diseases.

    价 格：￥电议型 号：T72421产 地：中国大陆

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