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T82549Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside;化合物 Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]
Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside (compound 9), a steroidal saponin, is isolated from the variety yunnanensis of Paris polyphylla, commonly known as Yunnan pine [1].
价 格:¥电议型 号:T82549产 地:中国大陆
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T82492EGFR/HER2/DHFR-IN-3;化合物 EGFR/HER2/DHFR-IN-3EGFR/HER2/DHFR-IN-3
EGFR/HER2/DHFR-IN-3 (compound 4c) serves as an efficacious dual inhibitor specifically targeting EGFR/HER2, exhibiting IC50 values of 0.138 μM for EGFR and 0.092 μM for HER2, respectively. Moreover, it demonstrates inhibition of DHFR with an IC50 of 0.193 μM. Notably, this compound induces cell cycle arrest in the S phase and triggers apoptosis in MCF7 breast cancer cells [1].
价 格:¥电议型 号:T82492产 地:中国大陆
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T82408Ferroptosis-IN-3;化合物 Ferroptosis-IN-3Ferroptosis-IN-3
Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM). It exhibits radical scavenging abilities against DPPH and ABTS (EC50: 3.94 and 6.3 μM, respectively), and effectively reduces lipid peroxidation [1].
价 格:¥电议型 号:T82408产 地:中国大陆
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T82294GLUT1-IN-3;化合物 GLUT1-IN-3GLUT1-IN-3
GLUT1-IN-3 (Compd 4b), a compound under investigation for type 1 glucose transporter deficiency syndrome, effectively inhibits seizures [1].
价 格:¥电议型 号:T82294产 地:中国大陆
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T82214Herbacetin-3-sophoroside-8--glucoside;化合物 Herbacetin-3-sophoroside-8--glucosideHerbacetin-3-sophoros
Herbacetin-3-sophoroside-8-glucoside is a naturally occurring compound that can be extracted from Equisetum hyemale [1].
价 格:¥电议型 号:T82214产 地:中国大陆
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T82163Human enteropeptidase-IN-3;化合物 Human enteropeptidase-IN-3Human enteropeptidase-IN-3
Human enteropeptidase-IN-3 is an inhibitor of enteropeptidase activity, characterized by extended duration of inhibition. It is applicable in the research of intestinal digestive-related diseases [1].
价 格:¥电议型 号:T82163产 地:中国大陆
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T82114ICMT-IN-3;化合物 ICMT-IN-3ICMT-IN-3
ICMT-IN-3 (Compound 27) serves as a potent inhibitor of ICMT, demonstrating an IC50 value of 0.015 μM [1].
价 格:¥电议型 号:T82114产 地:中国大陆
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T82113ICMT-IN-30;化合物 ICMT-IN-30ICMT-IN-30
ICMT-IN-30 (compound 67) is an ICMT inhibitor with an IC50 value of 0.27 μM [1].
价 格:¥电议型 号:T82113产 地:中国大陆
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T82112ICMT-IN-31;化合物 ICMT-IN-31ICMT-IN-31
ICMT-IN-31 (compound 68) serves as an ICMT inhibitor, demonstrating significant potency with an IC50 value of 0.0038 μM [1].
价 格:¥电议型 号:T82112产 地:中国大陆
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T82111ICMT-IN-32;化合物 ICMT-IN-32ICMT-IN-32
ICMT-IN-32 (compound 70) acts as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), demonstrating an IC50 value of 0.777 ?M [1].
价 格:¥电议型 号:T82111产 地:中国大陆
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T82110ICMT-IN-33;化合物 ICMT-IN-33ICMT-IN-33
ICMT-IN-33 (compound 73) functions as an ICMT inhibitor with an IC50 value of 0.46 μM [1].
价 格:¥电议型 号:T82110产 地:中国大陆
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T82109ICMT-IN-34;化合物 ICMT-IN-34ICMT-IN-34
ICMT-IN-34 (compound 39) serves as an effective inhibitor of ICMT, exhibiting an IC50 value of 0.17 μM [1].
价 格:¥电议型 号:T82109产 地:中国大陆
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T82108ICMT-IN-35;化合物 ICMT-IN-35ICMT-IN-35
ICMT-IN-35 (compound 10n), an ICMT inhibitor with an IC50 value of 0.8 μM, is a FTPA-triazole derivative. It demonstrates cellular uptake by mammalian cells, disrupts K-Ras membrane association, and induces K-Ras mislocalization. Additionally, ICMT-IN-35 exhibits selective cytotoxicity towards ICMT +/+ MEF cells and possesses potent activity against metastatic pancreatic cancer cell lines with an IC 50 of 0.8 μM [1].
价 格:¥电议型 号:T82108产 地:中国大陆
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T82107ICMT-IN-36;化合物 ICMT-IN-36ICMT-IN-36
ICMT-IN-36 (compound 40) serves as an ICMT inhibitor, with an IC50 value of 0.181 μM [1].
价 格:¥电议型 号:T82107产 地:中国大陆
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T82106ICMT-IN-37;化合物 ICMT-IN-37ICMT-IN-37
ICMT-IN-37 (compound 41) serves as an inhibitor of ICMT with an IC50 value of 0.308 μM [1].
价 格:¥电议型 号:T82106产 地:中国大陆
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T82105ICMT-IN-38;化合物 ICMT-IN-38ICMT-IN-38
ICMT-IN-38 (Compound 42) is an ICMT inhibitor, demonstrating an IC50 value of 0.049 μM [1].
价 格:¥电议型 号:T82105产 地:中国大陆
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T82104ICMT-IN-39;化合物 ICMT-IN-39ICMT-IN-39
ICMT-IN-39, also known as compound 18, functions as an inhibitor of ICMT with an IC50 value of 0.031 ?M [1].
价 格:¥电议型 号:T82104产 地:中国大陆
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T82023Ivicentamab;化合物 IvicentamabGEN-3009;GEN-3009
Ivicentamab (GEN-3009), an IgG1κ humanized monoclonal antibody targeting CD37, is utilized in cancer research [1].
价 格:¥电议型 号:T82023产 地:中国大陆
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T82018JAK-IN-33;化合物 JAK-IN-33JAK-IN-33
JAK-IN-33 (Compound 3 (R)) is a selective inhibitor of the Janus kinase (JAK) family [1].
价 格:¥电议型 号:T82018产 地:中国大陆
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T82017JAK-IN-34;化合物 JAK-IN-34JAK-IN-34
JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3, and 1.95 nM for TYK2. It effectively reduces joint swelling while maintaining a good safety profile [1].
价 格:¥电议型 号:T82017产 地:中国大陆