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T12419LPF-04634817PF-04634817
PF-0463481 is safe and well-tolerated and has the potential for the study of diabetic nephropathy. PF-0463481 is an effective and orally active dual CCR2/CCR5 antagonist. It also has comparable human and rodent CCR2 potency (rat IC50=20.8 nM). PF-0463481
价 格:¥电议型 号:T12419L产 地:美洲
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T12422PF-04957325PF-04957325
PF-04957325 is a selective inhibitor of PDE8(PDE8A and PDE8B with IC50s of 0.7 nM and 0.3 nM, respectively).
价 格:¥电议型 号:T12422产 地:美洲
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T12425PF-06424439 methanesulfonatePF-06424439 methanesulfonate
PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor(IC50 of 14 nM).
价 格:¥电议型 号:T12425产 地:美洲
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T12427PF-06700841 P-TosylatePF-06700841 P-Tosylate
PF-06700841 P-Tosylate is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s of 17 nM and 23 nM, respectively).
价 格:¥电议型 号:T12427产 地:美洲
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T12428LPF-06726304PF-06726304
PF-06726304 shows robust antitumor growth activity. PF-06726304 is an effective and selective EZH2 inhibitor. PF-06726304 inhibits wild-type and Y641N mutant EZH2 (Kis: 0.7 and 3.0 nM, respectively).
价 格:¥电议型 号:T12428L产 地:美洲
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T12429PF-06751979PF-06751979
PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).
价 格:¥电议型 号:T12429产 地:美洲
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T12431PF-06882961PF-06882961
PF-06882961 is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.
价 格:¥电议型 号:T12431产 地:美洲
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T12435Adriforant hydrochlorideAdriforant hydrochloride,PF-3893787 hydrochloride,
Adriforant hydrochloride is an antagonist of histamine H4 receptor.
价 格:¥电议型 号:T12435产 地:美洲
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T12436PF-543 CitratePF-543 Citrate,Sphingosine Kinase 1 Inhibitor II Citrate,
PF-543 Citrate is an inhibitor of sphingosine-competitive SPHK1(IC50 of 2 nM ).
价 格:¥电议型 号:T12436产 地:美洲
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T12437PF429242 dihydrochloridePF429242 dihydrochloride
PF429242 dihydrochloride is a reversible and competitive inhibitor of S1P (IC50 of 175 nM).
价 格:¥电议型 号:T12437产 地:美洲
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T12809(S)-PF-06873600(S)-PF-06873600
(S)-PF-06873600 is the S enantiomer of PF-06873600. PF-06873600 is a selective and orally bioavailable CDK inhibitor.
价 格:¥电议型 号:T12809产 地:美洲
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T12809LPF-06873600PF-06873600
PF-06873600 has potential antineoplastic activity. PF-06873600 is a selective and orally bioavailable inhibitor of cyclin-dependent kinase (Ki: 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively).
价 格:¥电议型 号:T12809L产 地:美洲
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T12884SfllrnpndkyepfSfllrnpndkyepf
Sfllrnpndkyepf is a synthetic thrombin receptor agonist peptide.
价 格:¥电议型 号:T12884产 地:美洲
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T14365AZ PFKFB3 26AZ PFKFB3 26
AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively[1]. AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM.
价 格:¥电议型 号:T14365产 地:美洲
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T15244Ertugliflozin L-pyroglutamic acidErtugliflozin L-pyroglutamic acid,PF-04971729 L-pyroglutamic acid,
Ertugliflozin L-pyroglutamic acid is selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (IC50: 0.877 nM for h-SGLT2). It also has the potential for the treatment of type 2 diabetes mellitus.
价 格:¥电议型 号:T15244产 地:美洲
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T16090MK-0773MK-0773,PF-05314882,
MK-0773 is a selective androgen receptor modulator that binds to AR (IC50: 6.6 nM).
价 格:¥电议型 号:T16090产 地:美洲
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T16471PerflubronPerflubron,Perfluorooctyl bromide,PFOB
Perflubron can be emulsified with egg phospholipids (EYP) and displays exceptionally fast excretion characteristics. Perflubron(1-Bromoheptadecafluorooctane; Heptadecafluorooctyl bromide; Perfluorooctyl bromide) is a contrast medium for magnetic resonance
价 格:¥电议型 号:T16471产 地:美洲
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T16478PF-04447943PF-04447943
PF-04447943 is an effective inhibitor of human recombinant PDE9A (IC50=12 nM). It has >78-fold selectivity, compared to other PDE family members (IC50>1000 nM).
价 格:¥电议型 号:T16478产 地:美洲
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T16479PF-04937319PF-04937319
PF-04937319 is designed to maintain glucose-lowering efficacy while mitigating the risk of hypoglycaemia observed with many other GKAs. PF-04937319 is a glucokinase activator (EC50: 154.4 ?μM), one of the most promising strategies for the treatment of typ
价 格:¥电议型 号:T16479产 地:美洲
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T16481PF-04995274PF-04995274
PF-04995274 is an effective, high-affinity, and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer´s disease. PF-04995274 has an EC50 range of 0.26-0.47 nM for hu
价 格:¥电议型 号:T16481产 地:美洲