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T41335cis-Vaccenic acid;顺-十八碳烯酸cis-11-Octadecenoic acid|||Asclepic acid|||(Z)-octadec-11-enoic acid;cis-11
cis-Vaccenic acid (Asclepic acid) is the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate. cis-Vaccenic acid acts a potential fetal hemoglobin inducer.
价 格:¥电议型 号:T41335产 地:中国大陆
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T40637Gondoic acid;顺-11-二十碳烯酸cis-11-Eicosenoicacid;cis-11-Eicosenoicacid|||顺-11-二十碳烯酸
Gondoic acid (cis-11-Eicosenoicacid) (cis-11-Eicosenoic acid) is a monounsaturated long-chain fatty acid that can be found in various plant oils and nuts [1].
价 格:¥电议型 号:T40637产 地:中国大陆
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T40111LBMS-1166-N-piperidine-CO-N-piperazine dihydrochloride;化合物T40111LBMS-1166-N-piperidine-CO-N-piperazin
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor that inhibits the PD-1/PD-L1 interaction with an IC50 of 39.2 nM.BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride contains the target protein PD-1/PD-L1 ligand and PROTAC linker.BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride can be used to synthesize PROTAC linker. BMS-1166-N-piperidine-CO-N-piperazine dihydro
价 格:¥电议型 号:T40111L产 地:中国大陆
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T40111BMS-1166-N-piperidine-CO-N-piperazine;BMS-1166-N-piperidine-CO-N-piperazineBMS-1166-N-piperidine-CO-
BMS-1166-N-piperidine-CO-N-piperazine is a chemical compound that contains a PD-1/PD-L1 immune checkpoint ligand and a PROTAC linker. It can be utilized in the synthesis of PROTAC PD-1/PD-L1 degrader-1, which effectively inhibits the PD-1/PD-L1 interaction, demonstrating an IC50 value of 39.2 nM.
价 格:¥电议型 号:T40111产 地:中国大陆
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T40110BMS-1166-N-piperidine-COOH;BMS-1166-N-piperidine-COOHBMS-1166-N-piperidine-COOH
BMS-1166-N-piperidine-COOH is a chemical compound that functions as the BMS-1166-based moiety. It binds to the E3 ligase ligand through a linker, leading to the formation of PROTAC PD-1/PD-L1 degrader-1, which facilitates the degradation of PD-1/PD-L1. BMS-1166 demonstrates potent inhibition of PD-1/PD-L1 interaction, with an IC 50 of 1.4 nM. By antagonizing the inhibitory effect of the PD-1/PD-L1 immune checkpoint on T cell activation, BMS-1166 promotes T cell activation.
价 格:¥电议型 号:T40110产 地:中国大陆
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T39999IACS-15414;IACS-15414IACS-15414
IACS-15414 is a potent SHP2 inhibitor that is effective when administered orally, demonstrating an IC50 value of 122 nM.
价 格:¥电议型 号:T39999产 地:中国大陆
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T39927Zeteletinib hemiadipateZeteletinib hemiadipateBOS-172738 hemiadipate|||DS-5010hemiadipate|||Zeteleti
Zeteletinib hemiadipate (BOS-172738; DS-5010) is an orally active compound that functions as a selective inhibitor of RET kinase. It exhibits nanomolar potency against RET and a 300-fold selectivity towards VEGFR2. Notably, Zeteletinib hemiadipate demonstrates exceptional effectiveness against various forms of RET, including the wild type, RET V804M/L gatekeeper mutants, and the oncogenic RET mutation M918T. Additionally, Zeteletinib hemiadipate exerts potent antitumor effects.
价 格:¥电议型 号:T39927产 地:中国大陆
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T39879JMS-17-2 hydrochloride;JMS-17-2 hydrochlorideJMS-17-2 hydrochloride
JMS-17-2 hydrochloride, a highly potent and selective CX3CR1 antagonist with an IC 50 value of 0.32 nM, effectively impedes the metastatic seeding and colonization process of breast cancer cells.
价 格:¥电议型 号:T39879产 地:中国大陆
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T39730Datopotamab deruxtecan;Datopotamab deruxtecanDato-DXd|||DS-1062;Dato-DXd|||DS-1062
Datopotamab deruxtecan (DS-1062; Dato-DXd) is an antibody-drug conjugate (ADC) that specifically targets trophoblast cell surface antigen 2 (TROP2). This compound exhibits high antitumor activity.
价 格:¥电议型 号:T39730产 地:中国大陆
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T39707AS-1763;化合物AS-1763AS-1763
AS-1763 is an orally available and selective BTK inhibitor with an IC50 of 0.85 nM.
价 格:¥电议型 号:T39707产 地:中国大陆
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T39491HS-131;HS-131HS-131
HS-131, a near-infrared dye-conjugated Hsp90 inhibitor, effectively identifies oncogene-driven breast cancers across various molecular subtypes.
价 格:¥电议型 号:T39491产 地:中国大陆
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T38779NS-102;NS-102NS-102
NS-102 is a powerful and selective antagonist of the kainate receptor (GluK2), as well as a potent antagonist of the GluR6/7 receptor.
价 格:¥电议型 号:T38779产 地:中国大陆
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T37927Erucylamide;芥酸酰胺13-Docosenamide|||Erucyl amide|||cis-13-Docosenamide|||(Z)-Docos-13-enamide;芥酸酰胺|||1
Erucylamide (13-Docosenamide) is an alkaloid found in Tadehagi triquetrum (L.) H.Ohashi.
价 格:¥电议型 号:T37927产 地:中国大陆
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T36695TAS-103;TAS-103 (BMS-247615)TAS-103
TAS-103 is a dual inhibitor of DNA topoisomerase I/II, used for cancer research.
价 格:¥电议型 号:T36695产 地:中国大陆
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T36570KUS121KUS121KUS-121|||KUS121
KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity (IC50= 330 nM).1It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, an inducer of ER stress, in HeLa cells when used at concentrations of 20, 50, and 50 μM, respectively. KUS121 (100 μM) inhibits ATP depletion and cell death induced by oxygen-glucose deprivation (OGD) in rat primary cortical neurons in anin vitromodel of cerebral ischemia.2It red
价 格:¥电议型 号:T36570产 地:中国大陆
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T3655BMS-1;化合物PD-1/PD-L1 inhibitor 1PD1-PDL1 inhibitor 1|||PD-1/PD-L1 inhibitor 1;PD1-PDL1 inhibitor 1|||
BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.
价 格:¥电议型 号:T3655产 地:中国大陆
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T36090S14161S14161S-14161|||S14161
S14161 has a wide range of applications in life science related research.
价 格:¥电议型 号:T36090产 地:中国大陆
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T35214Xylylcarb;化合物 T35214V-17004|||S 1042|||S-1042|||V 17004|||S1042;V-17004|||S 1042|||S-1042|||V 17004|
Xylylcarb is a biochemical.
价 格:¥电议型 号:T35214产 地:中国大陆
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T35139WS 1279;化合物 T35139WS1279|||WS-1279;WS1279|||WS-1279
WS 1279 is an immunoactive lipopeptide that is isolated from Streptomyces.
价 格:¥电议型 号:T35139产 地:中国大陆
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T34846Thiazolinobutazone;化合物 T34846LAS-11871|||LAS 11871|||LAS11871|||TZB;LAS-11871|||LAS 11871|||LAS11871
Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.
价 格:¥电议型 号:T34846产 地:中国大陆