T8906NBI-31772inhibit,IGF-responsive diseases,IGF-1R,IGFBP,NBI-31772,Inhibitor

NBI-31772 is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM). NBI-31772 can be used in research on IGF-responsive diseases.

价 格：￥电议型 号：T8906产 地：中国大陆

T7685USP25/28 inhibitor AZ1Deubiquitinase,USP-25/28 inhibitor AZ1,USP25/28 inhibitor AZ1,inhibit,AZ 1,Inh

USP25/28 inhibitor AZ1 (AZ1) is an inhibitor of ubiquitin specific protease (USP) 25/28

价 格：￥电议型 号：T7685产 地：中国大陆

TN7112(25R)-3β,17α-dihydroxy-5α- spirostan-6-one3-O-α-L- rhamnopyranosyl-(1→2)-β- D-glucopyranoside(25R)3β

(25R)-3β,17α-dihydroxy-5α- spirostan-6-one3-O-α-L- rhamnopyranosyl-(1→2)-β- D-glucopyranoside is a natural product isolated from the bulbs of Lilium brownii var. viridulum.

价 格：￥电议型 号：TN7112产 地：中国大陆

T63918α-Tocopherol phosphate disodium

α-Tocopherol phosphate (alpha-Tocopherol phosphate) is an antioxidant that scavenges UVA1-induced reactive oxygen species (ROS) and protects against long-wave UVA1-induced cell death. alpha-Tocopherol phosphate disodium impedes endothelial progenitor cell apoptosis, enhances endothelial progenitor cell migration under high glucose/low oxygen conditions and promotes angiogenesis. α-Tocopherol phosphate disodium prevents apoptosis, enhances migration of endothelial progenitor cells under high gluc

价 格：￥电议型 号：T63918产 地：中国大陆

T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,

MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode

价 格：￥电议型 号：T9303产 地：中国大陆

T7122AZD-7648DNA-dependent protein kinase,inhibit,Apoptosis,AZD7648,A549,OAW42,PI3K,Inhibitor,Phosphoinos

AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.

价 格：￥电议型 号：T7122产 地：中国大陆

T28118MSP3MSP3

MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.

价 格：￥电议型 号：T28118产 地：中国大陆

T7849NorspermineNorspermine

Norspermine is a polyamine analogue ,used in the treatment of non-small cell lung carcinoma and breast cancer.

价 格：￥电议型 号：T7849产 地：中国大陆

T7542Amino TadalafilPhosphodiesterase (PDE),Inhibitor,Amino Tadalafil,inhibit

Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.

价 格：￥电议型 号：T7542产 地：中国大陆

T4518Licochalcone DLicochalcone D,Apoptosis,A375,anti-cancer,antioxidant,Reactive Oxygen Species,Nuclear

Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotective potential against myocardial ischemia/reperfusion injury in langendorff-perfused rat hearts. Licochalcone D has anti-inflammatory activity, it shows suppression ability of nitric oxide (NO) production. Licochalcone D has anti-allergic activity, it suppresses degranulation by

价 格：￥电议型 号：T4518产 地：中国大陆

T6712Tyrphostin AG 879tyrosine,EGFR,phosphorylation,Tyrphostin AG-879,antiproliferation,Tyrphostin AG879,

Tyrphostin AG 879 effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.

价 格：￥电议型 号：T6712产 地：中国大陆

T6521GSK 2830371GSK-2830371,Inhibitor,GSK 2830371,Phosphatase,inhibit

GSK2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.

价 格：￥电议型 号：T6521产 地：中国大陆

TN1674Garcinone DKeap1-Nrf2,inhibit,Reactive Oxygen Species,Garcinone D,Inhibitor,STAT

Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 activation with IC50 values of 3.2 microM.

价 格：￥电议型 号：TN1674产 地：中国大陆

T9297PerseitolPerseitol,inhibit,energy-providing,Inhibitor,mature avocado plants,transport carbohydrate,D

Perseitol is a sugar that is specific to avocado honey. Perseitol have recently been reported as candidate biomarkers for avocado intake.

价 格：￥电议型 号：T9297产 地：中国大陆

TQ0212GlucoraphaninReactive Oxygen Species,Glucoraphanin,Inhibitor,inhibit

Glucoraphanin, the precursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, has antioxidant activity.

价 格：￥电议型 号：TQ0212产 地：中国大陆

TP1616LHsp70-derived octapeptide acetateHsp70derived octapeptide acetate,Hsp70 derived octapeptide acetate,

Hsp70-derived octapeptide acetate is a group of tetratricopeptide repeat (TPR)-containing proteins has been shown to interact with the C-terminal domain of the 70 kDa heat-shock cognate protein (hsc70). In the present study, the effect of the TPR-containing proteins, including the C-terminus of hsc70-interacting protein (CHIP), TPR1 and human glutamine-rich TPR-containing protein (hSGT), on refolding of luciferase by DnaJ and hsc70 was investigated.

价 格：￥电议型 号：TP1616L产 地：中国大陆

T65979Adenosine 5′-monophosphate disodium salt

价 格：￥电议型 号：T65979产 地：中国大陆

T6680StaurosporineAntibiotic AM2282,Antibiotic,Apoptosis,PKC,Antibiotic AM 2282,AM2282,Protein kinase A,B

Staurosporine is a potent PKC inhibitor for PKCα/γ/η (IC50: 2/5/4 nM), less potent to PKCε (73 nM), PKCδ (20 nM) and little action to PKCζ (1086 nM).

价 格：￥电议型 号：T6680产 地：中国大陆

T6677SophocarpineApoptosis,Sophocarpine,Influenza Virus,PI3K,Phosphoinositide 3-kinase,Inhibitor,Autophag

Sophocarpine has anti-cancer, anti-inflammatory, anti-nociceptive, and antivirus activities, it can prevent implant loosening through inhibiting osteoclast formation and bone resorption, thus, it may be a novel therapeutic agent to prevent prosthesis loosening and for osteolytic diseases. Sophocarpine could attenuate ConA-induced liver injury, and the protective effect of Sophocarpine was associated with its inhibition effect of pro-inflammatory cytokines, chemokines, and the IFN-γ/STAT1 signali

价 格：￥电议型 号：T6677产 地：中国大陆

TN1819Kaempferol 3-neohesperidosideinhibit,Kaempferol 3-neohesperidoside,Inhibitor,Kaempferol 3neohesperid

Kaempferol 3-neohesperidoside is a flavonoid. Kaempferol 3-neohesperidoside exhibits insulinomimetic effect on the rat soleus muscle.

价 格：￥电议型 号：TN1819产 地：中国大陆