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T7472918β-Glycyrrhetyl-3-O-sulfate;化合物 18β-Glycyrrhetyl-3-O-sulfate18β-Glycyrrhetyl-3-O-sulfate
18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) with an IC 50 value of 0.10 ?M in rat kidney microsome assays. This compound acts as a substrate for organic anion transporters (OAT) 1 and OAT3. It exhibits anti-inflammatory properties and holds potential for research into pseudohyperaldosteronism [1] [2].
价 格:¥电议型 号:T74729产 地:中国大陆
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T74684Abiraterone sulfate;化合物 Abiraterone sulfateAbiraterone sulfate
Abiraterone sulfate is a metabolite of Abiraterone . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1] .
价 格:¥电议型 号:T74684产 地:中国大陆
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T74579Ferulic acid 4-O-sulfate;化合物 Ferulic acid 4-O-sulfateFerulic acid 4-O-sulfate
Ferulic Acid 4-O-Sulfate (Ferulic Acid 4-Sulfate), a metabolite of Ferulic Acid, demonstrates vasorelaxant properties and reduces blood pressure in mice [1].
价 格:¥电议型 号:T74579产 地:中国大陆
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T73775Dopamine 3-O-sulfate;化合物 Dopamine 3-O-sulfateDopamine 3-O-sulfate
Dopamine 3-O-sulfate, primarily found in plasma, serves as a biomarker for identifying aromatic amino acid decarboxylase (AADC) deficiency [1].
价 格:¥电议型 号:T73775产 地:中国大陆
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T73772Estrone sulfate potassium;雌酮硫酸钾Estrone sulfate potassium
Estrone sulfate potassium is an estrogen ester and conjugate, a natural endogenous steroid.
价 格:¥电议型 号:T73772产 地:中国大陆
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T73758Glycolithocholic acid 3-sulfate;化合物 Glycolithocholic acid 3-sulfateGlycolithocholic acid 3-sulfate
Glycolithocholic acid 3-sulfate (SLCG), a cholic acid derivative and glycolithocholic acid metabolite, effectively inhibits HIV-1 replication in vitro. This compound holds potential for researching HIV infection and gallbladder disease [1] [2].
价 格:¥电议型 号:T73758产 地:中国大陆
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T72527Umbralisib sulfate;化合物 Umbralisib sulfateTGR-1202 sulfate ; RP-5264 sulfate|||TGR-1202 sulfate|||RP
Umbralisib (TGR-1202) sulfate, an orally active compound, serves as a potent, selective inhibitor targeting both PI3Kδ and casein kinase-1-ε (CK1ε), with EC50 values of 22.2 nM and 6.0 μM, respectively. It demonstrates unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL) and is applicable in the research of hematological malignancies.
价 格:¥电议型 号:T72527产 地:中国大陆
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T72430L-Kynurenine sulfate;化合物 L-Kynurenine sulfateL-Kynurenine sulfate
L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist, activates AHR-driven polarization of naive T cells towards the anti-inflammatory Treg phenotype.
价 格:¥电议型 号:T72430产 地:中国大陆
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T71429O-Demethyl apixaban sulfate;化合物 O-Demethyl apixaban sulfateO-Demethyl apixaban sulfate
O-Demethyl apixaban sulfate is a metabolite of Apixaban, a potent and highly selective factor Xa inhibitor. Apixaban is currently under development for treatment of arterial and venous thrombotic diseases.
价 格:¥电议型 号:T71429产 地:中国大陆
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T70933Weinbersterol disulfate A;化合物 Weinbersterol disulfate AWeinbersterol disulfate A
Weinbersterol disulfate A is a derivatives of 2beta,3alpha-dihydroxy-5alpha-cholestane. It has shown inhibitory action against HSV-2. and proved to be active against DEN-2 and JV.
价 格:¥电议型 号:T70933产 地:中国大陆
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T70837Rimegepant sulfate hydrate;化合物 Rimegepant sulfate hydrateRimegepant sulfate hydrate
Rimegepant, also known as BMS-927711 and BHV-3000, is a potent, selective, competitive, and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraines. Rimegepant has shown in vivo efficacy without vasoconstriction effect. BMS-927711 is superior to placebo at several different doses (75 mg, 150 mg, and 300 mg) and has an excellent tolerability profile.
价 格:¥电议型 号:T70837产 地:中国大陆
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T70408Rizatriptan sulfate;化合物 Rizatriptan sulfateRizatriptan sulfate
Rizatriptan sulfate is a selective serotonin 5-HTID receptor agonist derived from tryptamine.
价 格:¥电议型 号:T70408产 地:中国大陆
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T70313Indoxyl Sulfate-d5 potassium salt;化合物 Indoxyl Sulfate-d5 potassium saltIndoxyl Sulfate-d5 potassium
Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A1*2) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR) in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay).
价 格:¥电议型 号:T70313产 地:中国大陆
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T70014Avotaciclib sulfate;化合物 Avotaciclib sulfateAvotaciclib sulfate
Avotaciclib sulfate is a cyclin-dependent kinase inhibitor and antineoplastic.
价 格:¥电议型 号:T70014产 地:中国大陆
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T69865Mitapivat sulfate;化合物 Mitapivat sulfateMitapivat sulfate
Mitapivat sulfate, also known as AG-348 sulfate hydrate, is an allosteric activator of Pyruvate Kinase (PK) that may be useful in the treatment of Pyruvate Kinase Deficiency.
价 格:¥电议型 号:T69865产 地:中国大陆
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T69677Mitapivat sulfate anhydrous;化合物 Mitapivat sulfate anhydrousMitapivat sulfate anhydrous
Mitapivat sulfate anhydrous is an allosteric activator of Pyruvate Kinase (PK) that may be useful in the treatment of Pyruvate Kinase Deficiency.
价 格:¥电议型 号:T69677产 地:中国大陆
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T6967RHPS4;化合物RHPS4RHPS 4 methosulfate|||NSC714187;RHPS 4 methosulfate|||NSC714187
RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.
价 格:¥电议型 号:T6967产 地:中国大陆
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T69520Iroxanadine sulfate;化合物 Iroxanadine sulfateIroxanadine sulfate
Iroxanadine sulfate is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.
价 格:¥电议型 号:T69520产 地:中国大陆
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T69151Adrenaline sulfate;化合物 Adrenaline SulfateAdrenaline sulfate
Adrenaline sulfate, an orally active hormone secreted by the adrenal glands´ medulla, acts as an α-adrenergic and β-adrenergic receptor agonist. It is utilized in treating anaphylaxis and holds potential for cardiac arrest research.
价 格:¥电议型 号:T69151产 地:中国大陆
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T69089Trimethoprim sulfate;化合物 Trimethoprim sulfateTrimethoprim sulfate
Trimethoprim sulfate is a pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
价 格:¥电议型 号:T69089产 地:中国大陆