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T82383Fmoc-Lys(5-FITC)-OH;化合物 Fmoc-Lys(5-FITC)-OHFmoc-Lys(5-FITC)-OH
Fmoc-Lys(5-FITC)-OH serves as a fluorescent marker for polypeptides and proteins, utilizing FITC—a pH and Cu^2+-sensitive dye—as its fluorescence probe for amine labeling [1] [2] [3].
价 格:¥电议型 号:T82383产 地:中国大陆
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T82195HITCI;化合物 HITCIHITCI
HITCI, a commercially available cationic indocarbocyanine dye, is typically utilized as a laser dye within the near-infrared (NIR) [1] spectrum.
价 格:¥电议型 号:T82195产 地:中国大陆
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T81453PITCOIN4;化合物 PITCOIN4PITCOIN4
PITCOIN4 is a Class II Alpha PI3K-C2α inhibitor with high selectivity, demonstrating nanomolar inhibition of PI3K-C2α and exhibiting over 100-fold selectivity against a broad kinase panel [1].
价 格:¥电议型 号:T81453产 地:中国大陆
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T81355PTC258;化合物 PTC258PTC258
PTC258 is a specific, orally active modulator of the splicing of the Elongator complex protein 1 gene (ELP1), enhancing its expression both in vitro and in vivo. Additionally, PTC258 has demonstrated good tolerability in a mouse model [1].
价 格:¥电议型 号:T81355产 地:中国大陆
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T81353Pterostilbene-isothiocyanate;化合物 Pterostilbene-isothiocyanatePTER-ITC;PTER-ITC
Pterostilbene-isothiocyanate (PTER-ITC) demonstrates strong anticancer properties in vitro, particularly disrupting the interaction between β-catenin and TCF-4 in human osteosarcoma cells [1].
价 格:¥电议型 号:T81353产 地:中国大陆
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T81314Rademikibart;化合物 RademikibartCBP-201;CBP-201
Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, without cross-reactivity to IL-4Rα from other species. It effectively inhibits IL-4 and IL-13-induced STAT6 signaling, TF-1 cell proliferation, and TARC production in PBMCs, showing promise for investigating moderate-to-severe Th2 inflammatory diseases [1].
价 格:¥电议型 号:T81314产 地:中国大陆
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T81098Stapokibart;化合物 StapokibartCM310;CM310
Stapokibart (CM310), a humanized monoclonal antibody, selectively binds to IL-4Rα, inhibiting the cytokines IL-4 and IL-13 from interacting with their shared co-receptor subunit, IL-4Rα. This compound demonstrates cross-species reactivity by interacting with IL-4Rα in humans, cynomolgus monkeys, and rats [1].
价 格:¥电议型 号:T81098产 地:中国大陆
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T81061Sulfo-Cy5-TCO;化合物 Sulfo-Cy5-TCOSulfo-Cy5-TCO
Sulfo-Cy5-TCO, a water-soluble click chemistry reagent with a TCO group, exhibits high reactivity towards tetrazines and methyltetrazines, facilitating rapid bioconjugation [1].
价 格:¥电议型 号:T81061产 地:中国大陆
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T81033TAT-P4-(DATC5)2;化合物 TAT-P4-(DATC5)2TAT-P4-(DATC5)2
TAT-P4-(DATC5)2 is a potent peptide inhibitor targeting the PDZ domain of protein interacting with C kinase-1 (PICK1), exhibiting a high affinity with a dissociation constant (K_i) of 1.7 nM. This compound has demonstrated the capacity to mitigate addiction behaviors in rat models [1].
价 格:¥电议型 号:T81033产 地:中国大陆
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T81032TAT-P4-(DATC5)2 TFA;化合物 TAT-P4-(DATC5)2 TFATAT-P4-(DATC5)2 TFA
TAT-P4-(DATC5)2 TFA, a high-affinity peptide inhibitor targeting the PDZ domain of protein interacting with C kinase-1 (PICK1), exhibits a K i of 1.7 nM and demonstrates potential in mitigating addiction behaviors in rats [1].
价 格:¥电议型 号:T81032产 地:中国大陆
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T81027TCRS-417;化合物 TCRS-417T417;T417
TCRS-417 (T417), a small molecule compound, selectively binds to the interface between PBX1 and its specific DNA target sequence, disrupting the PBX1-DNA interaction. This compound has potential research applications in cancer, developmental, inflammatory, autoimmune, and neurodegenerative diseases [1].
价 格:¥电议型 号:T81027产 地:中国大陆
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T80959Trabikibart;化合物 TrabikibartCSL311;CSL311
Trabikibart (CSL311), a βc-specific, fully human monoclonal antibody, specifically binds to the cytokine-binding epitope of the human βc receptor with picomolar affinity. It potently inhibits the collective impact of IL-3, GM-CSF, and IL-5 on eosinophil survival, underscoring its potential in chronic inflammatory diseases research [1].
价 格:¥电议型 号:T80959产 地:中国大陆
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T80688β-Patchoulene;化合物 β-Patchouleneβ-Patchoulene
β-Patchoulene, a tricyclic sesquiterpene extracted from Pogostemon cablin (patchouli oil), has potential therapeutic applications in the treatment of inflammatory diseases [1].
价 格:¥电议型 号:T80688产 地:中国大陆
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T80598Davoceticept;化合物 DavoceticeptCD80 vIgD-Fc|||ALPN-202;CD80 vIgD-Fc|||ALPN-202
Davoceticept (ALPN-202; CD80 vIgD-Fc), a monoclonal antibody that targets CTLA-4, is comprised of the (1-107) fragment of CD80 fused to the IGHG1 Fc domain through a peptidyl linker. It is commonly produced in CHO (Chinese Hamster Ovary) cells [1].
价 格:¥电议型 号:T80598产 地:中国大陆
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T80541TCMCB07 TFA;化合物 TCMCB07 TFATCMCB07 TFA
TCMCB07 TFA is a cyclic nonapeptide and an orally active, brain-penetrating antagonist of the melanocortin receptor 4 (MC4R), playing a significant role in managing cachexia [1].
价 格:¥电议型 号:T80541产 地:中国大陆
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T80540TCMCB07;化合物 TCMCB07TCMCB07
TCMCB07, a cyclic nonapeptide, serves as an orally active, brain-penetrant antagonist of the melanocortin receptor 4 (MC4R), with significant implications in the management of cachexia [1].
价 格:¥电议型 号:T80540产 地:中国大陆
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T80474Citrullinated LL-37 4cit;化合物 Citrullinated LL-37 4citCitrullinated LL-37 4cit
Citrullinated LL-37 3cit, a modified form of the LL-37 peptide, exhibits no antiviral activity at a concentration of 10 μg/mL while maintaining partial efficacy against HRV at 30 μg/mL. Furthermore, this citrullinated variant demonstrates diminished immunomodulatory properties compared to the native LL-37 and a moderate reduction in its capacity to decrease HRV-induced CCL5 secretion [1].
价 格:¥电议型 号:T80474产 地:中国大陆
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T80473Citrullinated LL-37 3cit;化合物 Citrullinated LL-37 3citCitrullinated LL-37 3cit
Citrullinated LL-37 3cit is a host defense peptide with potent immunomodulatory and antimicrobial properties, demonstrating direct antiviral activity against human rhinoviruses (HRV) [1].
价 格:¥电议型 号:T80473产 地:中国大陆
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T80470Citrullinated LL-37 2cit;化合物 Citrullinated LL-37 2citCitrullinated LL-37 2cit
Citrullinated LL-37 2cit, a modified version of the LL-37 peptide, attenuates the antiviral efficacy of LL-37 against Human Rhinovirus (HRV) at a concentration of 10 μg/mL and diminishes its antibacterial properties. Furthermore, the compound diminishes RV1B-induced mRNA expression of pro-inflammatory cytokines IL-8, CCL5, and IL-6, and demonstrates a moderate decline in suppressing HRV-stimulated CCL5 secretion [1].
价 格:¥电议型 号:T80470产 地:中国大陆
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T80469Citrullinated LL-37 1cit;化合物 Citrullinated LL-37 1citCitrullinated LL-37 1cit
Citrullinated LL-37 1cit, a modified LL-37 peptide, retains the antiviral properties of its parent compound against human rhinovirus and exhibits antibacterial activity against S. aureus. Furthermore, it diminishes the RV1B-induced expression of pro-inflammatory cytokines, including IL-8, CCL5, and IL-6 mRNA [1].
价 格:¥电议型 号:T80469产 地:中国大陆