当前位置：易推广 > 上海陶术生物科技有限公司 > 产品展示
企业档案
会员类型：会员
已获得易推广信誉 等级评定
(0 -40)基础信誉积累，可浏览访问
(41-90)良好信誉积累，可接洽商谈
(91+ )优质信誉积累，可持续信赖
易推广会员：5年
工商认证 【已认证】
最后认证时间：
注册号： 【已认证】
法人代表： 【已认证】
企业类型：生产商 【已认证】
注册资金：人民币万 【已认证】
产品数：86101
参观次数：3500834
自主品牌
已选条件
-
T4532LLinrodostat mesylate；化合物 T4532LONO-7701|||BMS-986205|||ONO 7701|||BMS986205|||BMS 986205；ONO-7701|||
Linrodostat (BMS-986205, ONO-7701, and F001287) is a selective and orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. By inhibiting IDO1 and reducing kynurenine in tumor cells, BMS-986205 restores and promotes the proliferation and activation of various immune cells and causes a reduction in tumor-associated regulatory T cells (Tregs).
价 格：￥电议型 号：T4532L产 地：中国大陆
-
T4342PF-04929113 Mesylate；化合物PF-04929113 MesylatePF-04929113 (Mesylate)|||SNX-5422 Mesylate；PF-04929113 (
PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37 nM).
价 格：￥电议型 号：T4342产 地：中国大陆
-
T4310L2Prexasertib mesylate；化合物 T4310L2LY-2606368|||LY2606368|||LY 2606368；LY-2606368|||LY2606368|||LY 2606
Prexasertib is a potent and selective Chk1/Chk2 inhibitor. Prexasertib increases the effectiveness of conventional therapy in B-/T- cell progenitor acute lymphoblastic leukemia. LY2606368 causes replication catastrophe and antitumor effects through CHK1-dependent mechanisms. Treatment of cells with LY2606368 results in the rapid appearance of TUNEL and pH2AX-positive double-stranded DNA breaks in the S-phase cell population.
价 格：￥电议型 号：T4310L2产 地：中国大陆
-
T41194FFN 102 mesylate；FFN 102甲磺酸盐FFN 102 mesylate
FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN), a selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.FFN 102 mesylate is a Ph-responsive fluorescent pseudoneurotransmitter (FFN) that acts as a substrate for selective dopam
价 格：￥电议型 号：T41194产 地：中国大陆
-
T41184Clocinnamox mesylateClocinnamox mesylateC-CAM|||NIH 10443
Clocinnamox mesylate is a systemically active, irreversibleμ-opioid receptor antagonist (apparent Kivalues are 0.7, 1.9 and 5.7 nM for mouseμ,δandκreceptors respectively).
价 格：￥电议型 号：T41184产 地：中国大陆
-
T40504N-Desmethyl imatinib mesylate；N-Desmethyl imatinib mesylateImatinibmetaboliteN-Desmethylimatinibmesy
Norimatinib mesylate, also known as N-Desmethyl imatinib mesylate, is a metabolite derived from Imatinib, which acts as a potent multi-target inhibitor of v-Abl, c-Kit, and PDGFR.
价 格：￥电议型 号：T40504产 地：中国大陆
-
T4042Talabostat mesylate；化合物Talabostat mesylateVal-boroPro|||PT100；Val-boroPro|||PT100
Talabostat mesylate (PT100) is an orally active, selective inhibitor of dipeptidyl peptidases IV (DPP4, IC50: 0.18 nM), including tumor-associated fibroblast activation protein. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony-stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis.
价 格：￥电议型 号：T4042产 地：中国大陆
-
T39670Oritinib mesylateOritinib mesylateSH-1028 mesylate|||Oritinib mesylate
Oritinib mesylate (SH-1028) is a highly selective, orally active, pyrimidine-based irreversible inhibitor of epidermal growth factor receptor (EGFR) with a low half maximal inhibitory concentration (IC50) of 18 nM. It demonstrates potent efficacy against both EGFR-sensitive and resistant (T790M) mutations. Furthermore, Oritinib mesylate effectively suppresses the proliferation of tumor cells harboring EGFR mutations, regardless of their sensitivity or resistance.
价 格：￥电议型 号：T39670产 地：中国大陆
-
T39555Belumosudil mesylateBelumosudil mesylateSLx-2119mesylate|||KD025 mesylate
Belumosudil mesylate (KD025 mesylate) is a compound that selectively inhibits ROCK2, demonstrating IC50 values of 105 nM for ROCK2 and 24 μM for ROCK1. It possesses anti-fibrotic properties.
价 格：￥电议型 号：T39555产 地：中国大陆
-
T39439Seclidemstat mesylateSeclidemstat mesylateSP-2577 mesylate
Seclidemstat mesylate (SP-2577) is a highly effective and reversible inhibitor of KDM1A (LSD1), with a Ki of 31 nM and an IC 50 of 13 nM. It demonstrates significant potential in promoting antitumor immunity in switch/sucrose nonfermentable (SWI/SNF) complex mutated ovarian cancer, while also exhibiting inhibitory effects on virus production, viral DNA replication, and late gene expression. Seclidemstat mesylate is a valuable tool for studying Ewing Sarcoma in research settings.
价 格：￥电议型 号：T39439产 地：中国大陆
-
T38620Prexasertib dimesylate；Prexasertib dimesylateLY2606368 dimesylate；LY2606368 dimesylate
Prexasertib dimesylate (LY2606368 dimesylate) is a highly selective ATP-competitive second-generation inhibitor of checkpoint kinase 1 (CHK1). With a K i of 0.9 nM and an IC 50 of <1 nM, Prexasertib dimesylate effectively inhibits CHK2 (IC 50 = 8 nM) and RSK1 (IC 50 = 9 nM). Its mechanism of action involves inducing double-stranded DNA breakage and replication catastrophe, ultimately leading to apoptosis. Moreover, Prexasertib dimesylate demonstrates potent anti-tumor activity.
价 格：￥电议型 号：T38620产 地：中国大陆
-
T38521Patamostat mesylatePatamostat mesylateE-3123 mesylate
Patamostat mesylate (E-3123) is a highly potent protease inhibitor, displaying strong inhibitory activity against trypsin, plasmin, and thrombin, with IC 50 values of 39 nM, 950 nM, and 1.9 μM, respectively. This compound, Patamostat mesylate, shows promising potential in suppressing the pathogenesis and development of acute pancreatitis.
价 格：￥电议型 号：T38521产 地：中国大陆
-
T36903Rasagiline-13C3 (mesylate)；Rasagiline-13C3 (mesylate)Rasagiline-13C3 (mesylate)；Rasagiline-13C3 (mes
Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is selective for MAO-B over MAO-A (IC50= 412 nM for the rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 μM.2Rasagiline inhibits rat brain MAO-Bin vivo(ED50= 0.1 mg/kg).1It reduces cerebral ede
价 格：￥电议型 号：T36903产 地：中国大陆
-
T3689LRuboxistaurin mesylate；化合物 T3689LLY-333531|||LY333531|||LY 333531|||LY-333531 Mesylate；LY-333531|||L
Ruboxistaurin is a PKC beta inhibitor. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways. Ruboxistaurin inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt.
价 格：￥电议型 号：T3689L产 地：中国大陆
-
T3634Osimertinib mesylate；奥希替尼甲磺酸盐Mereletinib mesylate|||AZD-9291 mesylate；甲磺酸奥希替尼|||Mereletinib mesylate
Osimertinib mesylate (Mereletinib mesylate) is an irreversible and mutant selective EGFR inhibitor (IC50s: 12/1 nM for EGFR(L858R) and EGFR(L858R/T790M)).
价 格：￥电议型 号：T3634产 地：中国大陆
-
T35361AST5902 trimesylate；AST5902 trimesylateAST5902 trimesylate
AST5902 是alflutinib 在体外和体内的主要代谢产物，具有与alflutinib 相似的显着抗肿瘤活性。与alflutinib 相比，AST5902 表现出非常弱的 CYP3A4 诱导潜力。
价 格：￥电议型 号：T35361产 地：中国大陆
-
T3533Apilimod mesylate；阿吡莫德甲磺酸盐STA 5326 mesylate；阿吡莫德甲磺酸盐|||STA 5326 mesylate
Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.
价 格：￥电议型 号：T3533产 地：中国大陆
-
T35185LXorphanol mesylate；化合物 T35185LTR 5379M|||TR5379M|||TR-5379M；TR 5379M|||TR5379M|||TR-5379M
Xorphanol mesylate is a biochemical.
价 格：￥电议型 号：T35185L产 地：中国大陆
-
T34610LSemapimod mesylate；化合物 T34610LSemapimod tetramesylate；Semapimod tetramesylate
Semapimod mesylate is a biochemical.
价 格：￥电议型 号：T34610L产 地：中国大陆
-
T33946PF-06439015 mesylate；化合物 T33946PF 06439015|||PF-06439015|||PF06439015；PF 06439015|||PF-06439015|||PF
PF-06439015 overcomes clinical ALK (receptor tyrosine kinase anatropic lymphoma kinase) mutations resistant to krizotinib. Pf-06439015 is an effective selective inhibitor.
价 格：￥电议型 号：T33946产 地：中国大陆
