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  • T74723MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan；化合物 MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-ExatecanMC-Gly-

    MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is an agent-linker conjugate for antibody-drug conjugates (ADCs), incorporating Exatecan, a DNA Topoisomerase I inhibitor (IC 50 = 2.2 μM) [1].

    价 格：￥电议型 号：T74723产 地：中国大陆

  • T74720Mipomersen；化合物 MipomersenMipomersen

    Mipomersen (ISIS 301012 free base), an antisense oligonucleotide inhibitor of apolipoprotein B (apoB), exhibits an anti-HCV effect and reduces the infectivity of HCV. It is used in research targeting homozygous familial hypercholesterolemia (HoFH) [1] [2].

    价 格：￥电议型 号：T74720产 地：中国大陆

  • T74690Monarsen；化合物 MonarsenMonarsen

    Monarsen (EN101), a synthetic 20-base antisense oligodeoxynucleotide targeting the human AChE gene, is utilized in researching autoimmune myasthenia gravis (MG). This neuromuscular disorder is characterized by autoantibodies targeting the acetylcholine receptor (AChR).

    价 格：￥电议型 号：T74690产 地：中国大陆

  • T74590Boanmycin；化合物 BoanmycinBoanmycin

    Boanmycin, an antibiotic exhibiting antitumor activity, induces cellular senescence and apoptosis [1] [2] [3].

    价 格：￥电议型 号：T74590产 地：中国大陆

  • T74576Manusiran；化合物 ManusiranManusiran

    Manusiran is a potent TMPRSS6 (transmembrane protease serine 6) synthesis reducer [1] .

    价 格：￥电议型 号：T74576产 地：中国大陆

  • T74432Mongersen；化合物 MongersenMongersen

    Mongersen (GED-0301), a specific and orally active SMAD7 antisense oligonucleotide, enhances TGF-β1 activity, reducing inflammatory signals. It has been shown to alleviate experimental colitis resembling Crohn´s disease in mice [1] [2].

    价 格：￥电议型 号：T74432产 地：中国大陆

  • T74419Mulnitorsen；化合物 MulnitorsenMulnitorsen

    Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].

    价 格：￥电议型 号：T74419产 地：中国大陆

  • T74219Maximiscin；化合物 MaximiscinMaximiscin

    Maximiscin, a metabolite derived from fungi, causes DNA damage and exhibits selective cytotoxic activity towards a specific subtype of triple-negative breast cancer.

    价 格：￥电议型 号：T74219产 地：中国大陆

  • T73912Maysin；化合物 MaysinMaysin

    Maysin, a neuroprotective C-glycosyl-flavone isolated from corn silk, exhibits protective activity against Syn amyloid aggregates-oligomers and fibrils-induced damage. It prevents oxidative stress and imbalance of intracellular calcium homeostasis by activating an autophagic degradative process. Maysin is utilized in Parkinson´s disease (PD) research [1].

    价 格：￥电议型 号：T73912产 地：中国大陆

  • T73885Methyl gerfelin；化合物 Methyl gerfelinMethyl gerfelin

    Methyl gerfelin, a potent GLO1 inhibitor belonging to the flavonoid class [1] [2], suppresses osteoclast differentiation by targeting and binding three critical cellular proteins: glyoxalase 1 (GLO1), sterol binding protein 2 (SCP2), and small glutamine-rich tetratricopeptide repeat-containing protein A (SGTA).

    价 格：￥电议型 号：T73885产 地：中国大陆

  • T73720c(phg-isoDGR-(NMe)k) TFA；化合物 c(phg-isoDGR-(NMe)k) TFAc(phg-isoDGR-(NMe)k) TFA

    C(phg-isoDGR-(NMe)k) TFA is a selective and potent ligand for α5β1-integrin, exhibiting an IC50 of 2.9 nM [1].

    价 格：￥电议型 号：T73720产 地：中国大陆

  • T73702Mecasermin；化合物 MecaserminMecasermin

    Mecasermin (Human IGF-I; FK 780), a recombinant form of human insulin-like growth factor I (IGF-I), holds promise for investigating growth failure attributed to growth hormone (GH) insensitivity, which may be due to defects in GH receptors or the presence of GH-inhibiting antibodies [1].

    价 格：￥电议型 号：T73702产 地：中国大陆

  • T72662NMDAR/TRPM4-IN-2；化合物NMDAR/TRPM4-IN-2NMDAR/TRPM4-IN-2

    NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR/TRPM4-IN-2 has neuroprotective activity against NMDA-induced hippocampal neuronal cell death and mitochondrial dysfunction. NMDAR/TRPM4-IN-2 showed neuroprotective activity against NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons with an IC50 value of 2.1 μM.

    价 格：￥电议型 号：T72662产 地：中国大陆

  • T7130Navarixin；化合物NavarixinMK-7123|||SCH 527123；MK-7123|||SCH 527123

    Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in animal models, characteristics that may be beneficial in the treatment of conditions with unbalanced pulmonary neutrophilia.

    价 格：￥电议型 号：T7130产 地：中国大陆

  • T70957NMac1；化合物 NMac1NMac1

    NMac1is a small molecule phenylbutenoid dimer that has novel anti-proliferative effect only under glucose starvation in metastatic breast cancer cells. NMac1 causes significant activation of AMPK by decreasing ATP synthesis, lowers mitochondrial membrane potential (MMP, ΔΨm), and inhibits oxygen consumption rate (OCR) under glucose starvation. These effects of NMac1 are provoked by a consequence of OXPHOS complex I inhibition.

    价 格：￥电议型 号：T70957产 地：中国大陆

  • T70879Mirisetron；化合物 MirisetronMirisetron

    Mirisetron is a 5-HT3 receptor antagonist.

    价 格：￥电议型 号：T70879产 地：中国大陆

  • T70871Mipitroban；化合物 MipitrobanMipitroban

    Mipitroban is a thromboxane A2/prostaglandin H2 antagonist.

    价 格：￥电议型 号：T70871产 地：中国大陆

  • T70793Parogrelil Free Base；帕格雷利NM-702 Free Base；NM-702 Free Base

    Parogrelil Free Base (NM-702 Free Base) is a selective phosphodiesterase 3 inhibitor with bronchodilatory and anti-inflammatory effects, inhibits leukotriene (LT)D(4) and histamine-induced constriction of isolated guinea pig tracheal strips, and can be used in the study of bronchial asthma.

    价 格：￥电议型 号：T70793产 地：中国大陆

  • T70754NMS-P953；化合物 NMS-P953NMS-P953

    NMS-P953 is a JAK2 inhibitor, displaying significant tumor growth inhibition in SET-?2 xenograft tumor model. NMS-P953 has a mechanism of action confirmed in vivo by typical modulation of known biomarkers, and with a favorable pharmacokinetic and safety profile.

    价 格：￥电议型 号：T70754产 地：中国大陆

  • T70725Motuporin；化合物 MotuporinMotuporin

    Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac).

    价 格：￥电议型 号：T70725产 地：中国大陆

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