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T11122-(Hydroxymethyl)pyridine吡啶甲醇吡啶甲醇|||Piconol
2-(Hydroxymethyl)pyridine (Piconol) is used as an organic synthesis and medicinal chemistry intermediate for the synthesis of the stimulant laxative bisacodyl, and as a pyridinol with hypoglycemic activity.
价 格:¥电议型 号:T1112产 地:中国大陆
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T11098Droloxifene;屈洛昔芬3-Hydroxytamoxifen;3-Hydroxytamoxifen
Droloxifene (3-Hydroxytamoxifen), a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells.Fluroxifene has anti-estrogen and anti-implantation effects.Fluroxifene prevented bone loss in ovariectomized rats.
价 格:¥电议型 号:T11098产 地:中国大陆
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T10943D-(-)-Lactic acid;D-乳酸(R)-2-Hydroxypropionic acid;(R)-2-Hydroxypropionic acid|||D-乳酸
D-(-)-Lactic acid is a normal intermediate in sugar fermentation (oxidation, metabolism). It is identified as a competitive inhibitor of ProDH (proline dehydrogenase) in plants.
价 格:¥电议型 号:T10943产 地:中国大陆
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T10934D-Gluconic acid葡萄糖酸Dextronic acid|||Glycogenic acid|||Pentahydroxycaproic acid|||Gluconic acid|||D-G
D-Gluconic acid (D-Gluco-hexonic acid) is a carboxylic acid that has antiseptic and chelating properties through oxidation.
价 格:¥电议型 号:T10934产 地:中国大陆
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T10862Collagen proline hydroxylase inhibitor;胶原蛋白脯氨酸羟化酶抑制剂Collagen proline hydroxylase inhibitor
Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.
价 格:¥电议型 号:T10862产 地:中国大陆
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T10835LCletoquine oxalate;化合物 T10835LDesethylhydroxychloroquine oxalate;Desethylhydroxychloroquine oxalate
Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatment.
价 格:¥电议型 号:T10835L产 地:中国大陆
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T10835Cletoquine;去乙基羟氯喹Desethylhydroxychloroquine;Desethylhydroxychloroquine
Cletoquine is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatment.
价 格:¥电议型 号:T10835产 地:中国大陆
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T10761Ceranib-2;化合物Ceranib-23-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-4-phenyl-1H-quinolin-2-one;3-[(E)-3-(4
Ceranib-2 (3-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-4-phenyl-1H-quinolin-2-one) is an inhibitor of ceramidase with an IC50 of 28 μM in SKOV3 cells. Ceranib-2 decreases levels of sphingosine and S1P, induces cell apoptosis and exhibits anticancer activity.
价 格:¥电议型 号:T10761产 地:中国大陆
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T10686Carvedilol metabolite 4-Hydroxyphenyl Carvedilol;化合物 T106864-Hydroxyphenyl Carvedilol|||4-Hydroxycar
4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol. Carvedilol is a beta-blocker/alpha-1 blocker.
价 格:¥电议型 号:T10686产 地:中国大陆
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T1068Dithranol;蒽林1,8,9-trihydroxyanthracene|||cignoline|||Anthralin;1,8,9-trihydroxyanthracene|||cignolin
Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.
价 格:¥电议型 号:T1068产 地:中国大陆
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T10509Xanthine oxidase-IN-1;黄嘌呤氧化酶IN14-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid;4-(3-Cyano-5
Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid and nucleotide intermediates.
价 格:¥电议型 号:T10509产 地:中国大陆
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T10399Atorvastatin 3-Deoxyhept-2E-Enoic Acid;化合物 T10399(2E)-2,3-Dehydroxy Atorvastatin;(2E)-2,3-Dehydroxy
Atorvastatin 3-Deoxyhept-2E-Enoic Acid is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
价 格:¥电议型 号:T10399产 地:中国大陆
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T10208A-69412;化合物A-69412N-1-(Fur-3-ylethyl)-N-hydroxyurea;N-1-(Fur-3-ylethyl)-N-hydroxyurea
A-69412 (N-1-(Fur-3-ylethyl)-N-hydroxyurea) is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase. It has the potential to treat ulcerative colitis and asthma, and possibly other inflammatory and allergic conditions.
价 格:¥电议型 号:T10208产 地:中国大陆
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T102009-Hydroxyellipticine hydrochloride;化合物 T102009-Hydroxyellipticine hydrochloride
9-Hydroxyellipticine hydrochloride is a inhibitor of Topo II and RyR. It exhibits antitumor, antioxidant and catecholamine-releasing activities. 9-Hydroxyellipticine hydrochloride inihibits Hela S-3 and 293T cells (IC50s: 1.6 μM and 1.2μM).
价 格:¥电议型 号:T10200产 地:中国大陆
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T1020Doxorubicin hydrochloride;盐酸阿霉素Adriamycin|||Doxorubicin (Adriamycin) HCl|||Hydroxydaunorubicin hydro
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitumor activity. Doxorubicin hydrochloride reduces the phosphorylation of AMPK and its downstream target protein acetyl coenzyme A carboxylase, and induces apoptosis and autophagy.
价 格:¥电议型 号:T1020产 地:中国大陆
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T101967α-Hydroxy-4-cholesten-3-one;化合物 T101967α-Hydroxy-4-cholesten-3-one
7α-Hydroxy-4-cholesten-3-one is an intermediate in the synthesis of bile acids from cholesterol. It is a PXR agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss and other diseases associated with defective bile acid biosynthesis.It is the physiological substrate for CYP8B1.
价 格:¥电议型 号:T10196产 地:中国大陆
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T10191L7-Chlorokynurenic acid;7-氯犬尿酸7-chloro-4-hydroxy-2-carboxyquinoline|||7-CKA;7-chloro-4-hydroxy-2-carb
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
价 格:¥电议型 号:T10191L产 地:中国大陆
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T101826-Hydroxybenzbromarone;6-羟基苯并溴马隆6-Hydroxybenzbromarone
6-Hydroxybenzbromarone is the major metabolite of Benzbromarone. 6-Hydroxybenzbromarone is a protein Eyes Absent 3 (EYA3) inhibitor (IC50: 21.5 μM). It is an angiogenic agent, has strong inhibitory effects on cell migration, tubulogenesis, and angiogenic sprouting.
价 格:¥电议型 号:T10182产 地:中国大陆
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T101715-Hydroxypyrazine-2-Carboxylic Acid;化合物 T101715-Hydroxypyrazine-2-Carboxylic Acid
5-Hydroxypyrazine-2-Carboxylic Acid is a metabolite of anti-tuberculosis drug pyrazinamide.
价 格:¥电议型 号:T10171产 地:中国大陆
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T101645,6-Dihydroxyindole;5,6-二羟基吲哚Dopamine lutine;Dopamine lutine
5,6-Dihydroxyindole (Dopamine lutine) is a melanin precursor and has a broad-spectrum antibacterial, antiviral, antifungal, antiparasitic activity. It has cytotoxic effects and is strongly toxic against various pathogens.
价 格:¥电议型 号:T10164产 地:中国大陆