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T13911Tacalcitol monohydrate;他卡西醇一水物Curatoderm monohydrate|||TV 02 monohydrate|||TV-02H monohydrate|||1,24
Tacalcitol monohydrate(Curatoderm monohydrate), a vitamin D3 analog that promotes bone development by regulating calcium ions, can be used to study psoriasis.
价 格:¥电议型 号:T13911产 地:中国大陆
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T13898SPD-473 citrate;化合物 T13898SPD-473 citrate
SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.
价 格:¥电议型 号:T13898产 地:中国大陆
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T13799NQO1 substrateNQO1底物NQO-1 substrate|||NQO1 substrate
NQO1 substrate is a highly potent NQO1 substrate with potential antitumor activity for leukemia research.
价 格:¥电议型 号:T13799产 地:中国大陆
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T13742LIvacaftor hydrate;化合物 T13742LVX-770 hydrate;VX-770 hydrate
Ivacaftor hydrate is an orally bioavailable CFTR potentiator. It also is used for cystic fibrosis treatment.
价 格:¥电议型 号:T13742L产 地:中国大陆
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T13728Hydrocortisone buteprate;化合物 T13728HBP|||Hydrocortisone probutate;HBP|||Hydrocortisone probutate
Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders.
价 格:¥电议型 号:T13728产 地:中国大陆
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T13578Betamethasone-17-butyrate-21-propionate;化合物 T13578Betamethasone-17-butyrate-21-propionate
Betamethasone-17-butyrate-21-propionate is a topical corticosteroid and may be used in the treatment of inflammatory skin diseases.
价 格:¥电议型 号:T13578产 地:中国大陆
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T13525Abiraterone metabolite 1;化合物 T135253β-OH-5α-Abi;3β-OH-5α-Abi
Abiraterone Metabolite 1, a 5β-reduced derivative of abiraterone, acts by inhibiting CYP17A1, thereby blocking androgen synthesis and extending survival in prostate cancer patients.
价 格:¥电议型 号:T13525产 地:中国大陆
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T13486Neurodegenerative Disorder-Targeting Compound 1;化合物 T13486Neurodegenerative Disorder-Targeting Compo
Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].
价 格:¥电议型 号:T13486产 地:中国大陆
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T13460(+)-Cevimeline hydrochloride hemihydrate;化合物 T13460(+)-AF102B hydrochloride hemihydrate|||(+)-SNI-20
(+)-Cevimeline hydrochloride hemihydrate ((+)-SNI-2011), a potent muscarinic receptor agonist, stands as a promising therapeutic candidate for treating xerostomia in Sjogren´s syndrome. This compound has demonstrated a broad pharmacological profile across various systems including gastrointestinal, urinary, and reproductive, in animal models such as mice, rats, guinea pigs, rabbits, and dogs. Its metabolism was assessed in vitro using rat and dog liver microsomes, revealing that (+)-SNI-20
价 格:¥电议型 号:T13460产 地:中国大陆
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T13446(S)-Rivastigmine D6 tartrate;酒石酸卡巴拉汀 D6(R)-Rivastigmine D6 tartrate;酒石酸卡巴拉汀 D6|||(R)-卡巴拉汀酒石盐酸-D6|||(
(S)-Rivastigmine D6 tartrate is the deuterium labeled (S)-Rivastigmine, and is an inhibitor of cholinesterase.
价 格:¥电议型 号:T13446产 地:中国大陆
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T13421(-)-Cevimeline hydrochloride hemihydrate;化合物 T13421(-)-SNI-2011|||(-)-AF102B hydrochloride hemihydra
Cevimeline hydrochloride hemihydrate ((-)-SNI-2011), a novel muscarinic receptor agonist, is being explored as a potential treatment for xerostomia in Sjogren´s syndrome, exhibiting an IC50 value indicative of its affinity for mAChR. This compound´s pharmacological effects on the gastrointestinal, urinary, and reproductive systems, alongside its impact on various tissues, were thoroughly examined in species including mice, rats, guinea pigs, rabbits, and dogs. The metabolic breakdown
价 格:¥电议型 号:T13421产 地:中国大陆
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T13413Zoniporide hydrochloride hydrate;化合物 T13413CP-597396 hydrochloride hydrate;CP-597396 hydrochloride h
Zoniporide hydrochloride hydrate is a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor. Zoniporide hydrochloride hydrate inhibits human NHE-1 with IC50 of 14 nM.
价 格:¥电议型 号:T13413产 地:中国大陆
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T13388LZaurategrast ethyl ester;化合物 T13388LUCB1184197|||CDP323;UCB1184197|||CDP323
Zaurategrast ethyl ester is the ethyl ester prodrug of CT7758 and is an α4β1/α4β7 integrin antagonist. It is used for the treatment of inflammatory and autoimmune disorders.
价 格:¥电议型 号:T13388L产 地:中国大陆
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T13388Zaurategrast ethyl ester sulfate;化合物 T13388UCB1184197 sulfate|||CDP323 sulfate;UCB1184197 sulfate|||
Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.
价 格:¥电议型 号:T13388产 地:中国大陆
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T13385Zamifenacin fumarate;扎非那星富马酸盐UK-76654 fumarate;扎非那星富马酸盐|||UK-76654 fumarate
Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.
价 格:¥电议型 号:T13385产 地:中国大陆
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T13376LYS-49 monohydrate (132836-42-1 free base);化合物 T13376LYS-49 monohydrate;YS-49 monohydrate
YS-49 (monohydrate) is an activator of PI3K/Akt (a downstream target of RhoA).
价 格:¥电议型 号:T13376L产 地:中国大陆
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T13336LVTP50469 fumarate;化合物 T13336LVTP50469 fumarate
VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity.
价 格:¥电议型 号:T13336L产 地:中国大陆
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T13324VUF11207 fumarate;化合物VUF11207 fumarateVUF11207 fumarate
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).
价 格:¥电议型 号:T13324产 地:中国大陆
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T13259URAT1 inhibitor 1;化合物 T13259URAT1 inhibitor 1
URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.
价 格:¥电议型 号:T13259产 地:中国大陆
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T13241UB 165 fumarate;化合物UB165富马酸UB-165 fumarate|||UB165 fumarate;UB-165 fumarate|||UB165 fumarate
UB 165 fumarate is an agonist of the nAChR, a partial agonist of the α4β2 subtype, and a full agonist of the α3β2 subtype, with a Ki value of 0.27 nM for binding to [3H]-nicotine measured in rat brain.
价 格:¥电议型 号:T13241产 地:中国大陆