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T37182AX 048;AX 048AX 048
The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes. AX 048 is a potent group IVA cPLA2 inhibitor that demonstrates 50% inhibition of the enzyme at a mole fraction (XI(50)) of 0.022. Pretreatment with AX 048 (ED50 = 1.2 mg/kg) dose-dependently reduces thermal hyperalgesia evoked by carrageenan injection of r
价 格:¥电议型 号:T37182产 地:中国大陆
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T37048LMMP-3 Inhibitor acetate;化合物MMP-3 Inhibitor acetateMMP-3 Inhibitor acetate(158841-76-0 Free base);MMP
MMP-3 Inhibitor acetate is a cell-permeable and potent inhibitor of human MMP-3.
价 格:¥电议型 号:T37048L产 地:中国大陆
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T37048MMP-3 Inhibitor;MMP-3抑制剂MMP-3 Inhibitor
MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.
价 格:¥电议型 号:T37048产 地:中国大陆
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T36549CAY10486;CAY10486CAY10486
Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM.
价 格:¥电议型 号:T36549产 地:中国大陆
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T36048Linearmycin A;Linearmycin ALinearmycin A
Linearmycin A is a polyene antibiotic that has been found inStreptomyces.1It is active against the bacteriaS. aureusandE. coli(MICs = 3.1 and 1.6 μg/disc, respectively), the fungiS. cerevisiaeandC. albicans(MICs = 0.1 and 1.6 μg/disc, respectively), and the plant pathogenic fungusA. nigerin disc assays (MIC = 0.2 μg/disc). Linearmycin A induces lysis and degradation ofB. subtilisas a component ofStreptomycesMg1 extract.2
价 格:¥电议型 号:T36048产 地:中国大陆
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T35985CAY10487CAY10487CAY-10487|||CAY10487
The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 inhibits formation of fatty streak lesions of the thoracic aorta in high cholesterol-fed rabbits without affecting plasma lipid profiles or significantly inhibiting ACAT-1 or ACAT-2 activity. The percent area occupied by the atherosclerotic lesion in rabbits supplemented with 0.05% CAY10487 in the diet was 16.1% compared to 53.5% in control rabbits.
价 格:¥电议型 号:T35985产 地:中国大陆
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T35984CAY10485;CAY10485CAY10485
Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10485 inhibits human ACAT-1 and ACAT-2 with an IC50 values of 95 and 81 μM, respectively. It also inhibits copper-mediated oxidation of low density lipoproteins by 91% at a concentration of 2 μM.
价 格:¥电议型 号:T35984产 地:中国大陆
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T35081VU0486321;化合物 T35081VU 0486321|||VU-0486321;VU 0486321|||VU-0486321
VU0486321 is a potent mGlu1 PAM with moderate rat PK (CLp = 13.3. mL/min/kg,t1/2 = 54 min), good free fraction (human fu = 0.05, rat fu =0.03) and excellent CNS penetration (Kp = 1.02).
价 格:¥电议型 号:T35081产 地:中国大陆
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T35048Verofylline;维罗茶碱CK 0383|||Verofilina|||CK-0383|||Verofyllinum|||CK0383;CK 0383|||Verofilina|||CK-038
Verofylline (Verofyllinum) is an orally available, long-acting, multiacting, methylxanthine-substituted bronchodilator with inhibitory effects on PDE4 for the treatment of asthma disease research obesity.
价 格:¥电议型 号:T35048产 地:中国大陆
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T34406RS 0481;化合物 RS 0481RS-0481|||RS0481;RS-0481|||RS0481
RS 0481 modulates the immune response and rebuilds lymphocyte populations damaged by tumor growth in animals.
价 格:¥电议型 号:T34406产 地:中国大陆
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T34123Pranazepide;普拉那西匹FR120480|||FK 480|||FR-120480;FR120480|||FK 480|||FR-120480
Pranazepide (FK 480) is a small molecule cholecystokinin receptor antagonist used to study digestive disorders and pancreatitis.
价 格:¥电议型 号:T34123产 地:中国大陆
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T3409Plantamajoside;车前子甙Y0160|||C10485;Y0160|||C10485|||大车前苷|||车前子甙
Plantamajoside (Y0160) has anti-hepatotoxic, anti-inflammatory, antinociceptive activities, improving sexual function and antioxidant activity.
价 格:¥电议型 号:T3409产 地:中国大陆
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T34048Phthalimide, N-(5-(4-amino-alpha-hydroxy-o-tolyloxy)pentyl)-;化合物 T34048Phthalimide, N-(5-(4-amino-al
Phthalimide, N-(5-(4-amino-alpha-hydroxy-o-tolyloxy)pentyl)- is a bioactive chemical.
价 格:¥电议型 号:T34048产 地:中国大陆
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T33943PF-04856264化合物 T33943PF-4856264|||PF4856264|||PF 4856264
PF-04856264 is a potent and selective human Nav1.7 voltage-gated sodium channel inhibitor (IC50 = 28 nM).
价 格:¥电议型 号:T33943产 地:中国大陆
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T33048Lysine amidotrizoate;化合物 T33048Lysine amidotrizoate
Lysine amidotrizoate is a bioactive chemical.
价 格:¥电议型 号:T33048产 地:中国大陆
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T32526Lactandrate;化合物 T32526NSC290205|||NSC 620482|||ASE|||NSC 290205|||NSC-290205;NSC290205|||NSC 620482|
Lactandrate is a homo-aza-steroidal ester of p-bis(2-chloroethyl) amino phenyl acetic acid.
价 格:¥电议型 号:T32526产 地:中国大陆
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T32048HC 9016;化合物 T32048HC 9016|||9016 HC|||9016-HC|||HC-9016|||9016 HC|||9016-HC|||HC-9016|||HC-9016|||90
HC 9016 is a biochemical.
价 格:¥电议型 号:T32048产 地:中国大陆
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T31048CP-320626;化合物 T31048CP 320626;CP 320626
CP-320626 is an effective inhibitor of glycogen phosphorylase A (LGPA) in the human liver and GPA in the human muscle. Can act synergistically with glucose. It is a possible target for the treatment of type 2 diabetes.
价 格:¥电议型 号:T31048产 地:中国大陆
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T30489BMS 181101;化合物 T30489BMS181101|||BMS-181101;BMS181101|||BMS-181101
BMS-181101 is a novel antidepressant that has pharmacological characteristics as a serotonin reuptake inhibitor and a serotonin 5-HT receptor agonist.
价 格:¥电议型 号:T30489产 地:中国大陆