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T81575PA22-2 free acid;化合物 PA22-2 free acidCys-Laminin A chain 2091-2108;Cys-Laminin A chain 2091-2108
PA22-2 (free acid) (Cys-Laminin A chain 2091-2108), a peptide, promotes neurite outgrowth and facilitates the formation of neuron-like processes. It is utilized in the culturing of human adenoid cystic carcinoma cells and the development of peptide-functionalized supported phospholipid bilayers [1] [2] [3].
价 格:¥电议型 号:T81575产 地:中国大陆
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T81108SR-1114;化合物 SR-1114SR-1114
SR-1114, a first-in-class PROTAC ENL degrader, induces rapid CRBN-dependent ENL degradation with DC50 values of 150 nM in MV4;11 cells, 311 nM in MOLM-13 cells, and 1.65 μM in OCI/AML-2 cells [1].
价 格:¥电议型 号:T81108产 地:中国大陆
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T81089Steroid sulfatase-IN-7;化合物 Steroid sulfatase-IN-7Steroid sulfatase-IN-7
Steroid sulfatase-IN-7 is an irreversible inhibitor of steroid sulfatase (STS), demonstrating potent activity with an IC50 of 0.05 nM against human placental STS, rendering it suitable for application in cancer research [1].
价 格:¥电议型 号:T81089产 地:中国大陆
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T81088Sterpurol D;化合物 Sterpurol DSterpurol D
Sterpurol D, a sterpurane sesquiterpenoid compound, significantly inhibits nitric oxide (NO) production [1].
价 格:¥电议型 号:T81088产 地:中国大陆
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T81087Stick Insect Hypertrehalosaemic Factor II;化合物 Stick Insect Hypertrehalosaemic Factor IIStick Insect
Stick Insect Hypertrehalosaemic Factor II, a synthetic peptide, exhibits identical FAB spectra, reversed-phase high-performance liquid chromatographic profiles (behavior), and biological activity (behavior) as its natural counterpart and is utilized in researching the hypertrehalosaemic effect [1].
价 格:¥电议型 号:T81087产 地:中国大陆
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T81086Stigmast-5-ene-3,7-dione;化合物 Stigmast-5-ene-3,7-dioneStigmast-5-ene-3,7-dione
Stigmast-5-ene-3,7-dione (Compound 10), isolated from the roots, leaves, and twigs of Penianthus longifolius [1], is a naturally occurring chemical entity.
价 格:¥电议型 号:T81086产 地:中国大陆
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T81085Stigmasta-3,5-dien-7-one;化合物 Stigmasta-3,5-dien-7-oneStigmasta-3,5-dien-7-one
Stigmasta-3,5-dien-7-one is a steroid derivative sourced from Harrisonia abyssinica [1].
价 格:¥电议型 号:T81085产 地:中国大陆
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T81084STING agonist-18;化合物 STING agonist-18STING agonist-18
STING Agonist-18 (Compound 1a) is a precursor for the synthesis of antibody-drug conjugates (ADCs), including Trastuzumab conjugates [1].
价 格:¥电议型 号:T81084产 地:中国大陆
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T81083STING agonist-19;化合物 STING agonist-19STING agonist-19
STING agonist-19 serves as a precursor for the synthesis of immune-stimulating antibody conjugates (ISACs).
价 格:¥电议型 号:T81083产 地:中国大陆
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T81082STING-IN-7;化合物 STING-IN-7STING-IN-7
STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of 11.5 nM. It effectively hampers the phosphorylation of both STING and interferon regulatory factor 3 (IRF3) [1].
价 格:¥电议型 号:T81082产 地:中国大陆
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T81081Stressin I TFA;化合物 Stressin I TFACyclo(31-34)[DPhe12,Nle21,38,Glu31,Lys34]Ac-hCRF(4-41) TFA;Cyclo(31
Stressin I (Cyclo(31-34)[DPhe12, Nle21, 38, Glu31, Lys34]Ac-hCRF(4-41)) TFA, with a K i of 1.7 nM, is a potent and selective agonist of the CRF1 receptor. It has been shown to elevate adrenocorticotropic hormone (ACTH) levels in rats [1].
价 格:¥电议型 号:T81081产 地:中国大陆
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T81080Strictinin;化合物 StrictininStrictinin
Strictinin, a phenolic compound extracted from Pu´er teas, exhibits antiviral, antibacterial, and laxative properties. Its mode of action involves speeding up intestinal transit without promoting gastric emptying, boosting food consumption, or triggering diarrhea in rats.
价 格:¥电议型 号:T81080产 地:中国大陆
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T8108Blu-782;化合物Blu-782ALK2-IN-1;ALK2-IN-1
Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)
价 格:¥电议型 号:T8108产 地:中国大陆
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T80108Hepcidin-1 (mouse);化合物 Hepcidin-1 (mouse)Hepcidin-1 (mouse)
Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion. This compound also reduces FPN1 protein levels and boosts intracellular iron, ultimately aiding in osteoclast differentiation [1].
价 格:¥电议型 号:T80108产 地:中国大陆
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T79908ON 108600;化合物 ON 108600ON 108600
ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.028 μM for DYRK2, 0.05 μM and 0.005 μM for CK2α1 and CK2α2, and 0.005 μM for TNIK, respectively. This compound exhibits antitumor activity [1].
价 格:¥电议型 号:T79908产 地:中国大陆
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T79108SHP2-IN-14;化合物 SHP2-IN-14SHP2-IN-14
SHP2-IN-14 (compound 27) is a potent, orally active allosteric inhibitor of SHP2, displaying strong anti-tumor activity with an IC50 of 7 nM. It inhibits tumor progression in NCI-H358 tumor-bearing mice and demonstrates favorable pharmacokinetic properties and safety [1].
价 格:¥电议型 号:T79108产 地:中国大陆
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T78693Anticancer agent 108;化合物 Anticancer agent 108Anticancer agent 108
Anticancer Agent 108 (Compound 3.10) serves as a potent P-gp inhibitor exhibiting considerable antitumor properties while maintaining reduced toxicity to both normal and pseudonormal cells; it also demonstrated no acute toxic effects on C57BL/6 mice [1].
价 格:¥电议型 号:T78693产 地:中国大陆
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T78399FD-1080 free acid;化合物 FD-1080 free acidFD-1080 free acid
FD-1080 free acid, an NIR-II region fluorophore (Ex=1064 nm, Em=1080 nm), facilitates in vivo imaging [1].
价 格:¥电议型 号:T78399产 地:中国大陆
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T78108?-Conotoxin-CnIIIC acetate;芋螺肽醋酸盐?-Conotoxin-CnIIIC acetate
?-Conotoxin-CnIIIC acetate is a potent NaV1.4 sodium channel antagonist, a conotoxin peptide consisting of 22 amino acids, used for muscle relaxation and pain relief.
价 格:¥电议型 号:T78108产 地:中国大陆
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T7723Carumonam Sodium;化合物 T7723Ro172301|||Ro-17-2301|||AMA1080|||AMA-1080|||Ro 17 2301|||AMA 1080;Ro17230
Carumonam Sodium is a monobactam, penicillin-binding protein inhibitor. It is used as antibacterials.
价 格:¥电议型 号:T7723产 地:中国大陆