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T11131DW14800DW14800,DW-14800
DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.
价 格:¥电议型 号:T11131产 地:中国大陆
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TN1113Vincetoxicoside BInhibitor,Fungal,ativity,inhibit,Vincetoxicoside B,antifungal
Vincetoxicoside B, isolated from Polygonum paleaceum Wall. Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activities with the FICI values <0.5.
价 格:¥电议型 号:TN1113产 地:中国大陆
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T9611PF-04802367PF367,PF 367,protein,disease,Alzheimer,PF-04802367,PF-367,Glycogen synthase kinase-3,kina
PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay. It shows desirable central nervous system (CNS) properties and potency. It is equally effective at inhibition of the two known GSK-3 isoforms (GSK-3α and GSK-3β) with IC50 values of 10.0 and 9.0 nM in mobility shift assays, respectively.
价 格:¥电议型 号:T9611产 地:中国大陆
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TN1134Euscaphic acidEuscaphic acid,Inhibitor,PI3K,inhibit,Apoptosis,Phosphoinositide 3-kinase,DNA/RNA Synt
Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction to downregulate NF-κB activations.
价 格:¥电议型 号:TN1134产 地:中国大陆
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T9003CVT-11127Inhibitor,apoposis,GS 456332,S-phase,monounsaturated fatty acids (MUFA),Stearoyl-CoA Desatu
CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.
价 格:¥电议型 号:T9003产 地:中国大陆
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TQ0113Iclapriminhibit,AR 100,Bacterial,Iclaprim,Inhibitor,Antibiotic,AR100
Iclaprim is a novel specific bacterial Dihydrofolate inhibitor. It can inhibit the growth of S. aureus (MIC90: 0.06 μg/mL).
价 格:¥电议型 号:TQ0113产 地:中国大陆
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T6930Pazopanib Hydrochlorideinhibit,CD117,CSF1R,GW-786034,Vascular endothelial growth factor receptor,col
Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
价 格:¥电议型 号:T6930产 地:中国大陆
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TP2221LANP (1-11), rat acetateANP (111), rat acetate,ANP (1 11), rat acetate
ANP (1-11), rat acetate is one of the atrial natriuretic factors, inhibitors of CRF-stimulated ACTH secretion.
价 格:¥电议型 号:TP2221L产 地:中国大陆
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TN2011OmbuosideGynostemma pentaphyllum,antimicrobial,Parkinson?s disease,Bacterial,inhibit,Ombuoside,bacte
Ombuoside has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.
价 格:¥电议型 号:TN2011产 地:中国大陆
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TP1134LHCGRP-(8-37) acetateHCGRP (8 37) acetate,HCGRP(837) acetate
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.
价 格:¥电议型 号:TP1134L产 地:中国大陆
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T11410LGLPG0492GLPG0492,GLPG-0492
GLPG0492 is a novel selective androgen receptor modulator. After oral dosing, it showed anabolic activity on muscle, strongly dissociated from the androgenic activity on the prostate.
价 格:¥电议型 号:T11410L产 地:中国大陆
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T7113ParadolInhibitor,inhibit,COX,Paradol,[6]-Paradol,Cyclooxygenase
6-paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activities,neuroprotective Effects.
价 格:¥电议型 号:T7113产 地:中国大陆
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T9689M4205factor,M-4205,receptor,M4205,cell,CD117,growth,inhibit,mast/stem,mutations,SCFR,c-Kit,M 4205,In
M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.
价 格:¥电议型 号:T9689产 地:中国大陆
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T7615LXenopsin 2TFA(51827-01-1(free base)Xenopsin 2TFA(51827 01 1(free base),Xenopsin 2TFA(51827011(free b
Xenopsin(2TFA) is a neurotensin-like octapeptide previously isolated from amphibian skin.
价 格:¥电议型 号:T7615L产 地:中国大陆
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T10965DBPR112DBPR-112,DBPR112
DBPR112 is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM and 48 nM for EGFRWT and EGFRL858R/T790M, respectively. DBPR112 can occupy the ATP-binding site. DBPR112 has significant antitumor efficacy.
价 格:¥电议型 号:T10965产 地:中国大陆
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TP1155LHuman growth hormone-releasing factor acetateHuman growth hormone releasing factor acetate,Human gro
Human growth hormone-releasing factor acetate is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary[1].
价 格:¥电议型 号:TP1155L产 地:中国大陆
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TP1168N-Formyl-Met-Leu-Phe-LysInhibitor,N Formyl Met Leu Phe Lys,inhibit,NFormylMetLeuPheLys
N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) binds specifically to receptors on leukocyte membranes. Uptake of chemotactic peptides can contribute to quantitative assessment of neutrophils in localized inflammatory processes and is independent of associated edema formation or microcirculatory compromise.
价 格:¥电议型 号:TP1168产 地:中国大陆
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T3511PF-1355
PF-1355 is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases.
价 格:¥电议型 号:T3511产 地:中国大陆
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T11090L1Aldoxorubicin hydrochloride
Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibits potent antitumor activities in various cancer cell lines and in murine tumor models.
价 格:¥电议型 号:T11090L1产 地:中国大陆