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T61722ZDLD20；化合物 ZDLD20ZDLD20
ZDLD20 is an orally active and selective CDK4 inhibitor, a β-carboline analog with anti-HCT116 and anticancer activity that inhibits colony formation, inhibits invasion and migration, induces apoptosis, and prevents the G1 phase of the cell cycle.
价 格：￥电议型 号：T61722产 地：中国大陆
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T61721RAGE 229；化合物 RAGE 229RAGE 229
RAGE 229, N-(4-(7-cyano-4-(morpholin-4ylmethyl) quinolin-2-yl)phenyl)acetamide, is an orally active ctRAGE-DIAPH1 inhibitor. RAGE 229 can inhibit the intracellular RAGE signaling by inhibiting the interaction between the cytoplasmic tail of RAGE(ctRAGE) and Diaphanous-1(DIAPH1) [1].
价 格：￥电议型 号：T61721产 地：中国大陆
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T61720Pol I-IN-1；化合物 Pol I-IN-1Pol I-IN-1
Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition concentration (IC50) of 0.21 μM [1].
价 格：￥电议型 号：T61720产 地：中国大陆
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T6172MRS 2578；化合物MRS 2578MRS 2578
MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.
价 格：￥电议型 号：T6172产 地：中国大陆
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T61172NRX-1532；化合物NRX-1532NRX1532|||NRX 1532；NRX1532|||NRX 1532
NRX-1532 is a small molecule β-catenin:β-TrCP interaction enhancer.
价 格：￥电议型 号：T61172产 地：中国大陆
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T5S1172Tiliroside；银椴甙Tribuloside；银椴甙|||Tribuloside|||银椴苷；椴树苷
1. Tiliroside (Tribuloside) shows anticarcinogenic activity. 2. Tiliroside shows hepatoprotective activity. 3. Tiliroside shows antioxidant and anti-inflammatory activity, can inhibit neuroinflammation in neurodegenerative disorders. 4. Tiliroside has anti-diabetic effect, are at least partially mediated through inhibitory effects on carbohydrate digestion and glucose uptake in the gastrointestinal tract. 5. Tiliroside and gnaphaliin are antioxidants against in vitro Cu(2+)-induced LDL oxidation
价 格：￥电议型 号：T5S1172产 地：中国大陆
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T5700PDD00017273；化合物PDD00017273PDD00017273
PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.
价 格：￥电议型 号：T5700产 地：中国大陆
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T5172AZ304；化合物AZ304AZ304
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).
价 格：￥电议型 号：T5172产 地：中国大陆
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T5124SRT 1720 dihydrochloride[925434-55-5(free base)]；化合物SRT 1720 dihydrochloride[SRT 1720 dihydrochlorid
SRT 1720 is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).
价 格：￥电议型 号：T5124产 地：中国大陆
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T5096SRT 1720化合物SRT 1720N-[2-[3-(1-哌嗪基甲基)咪唑并[2,1-B]噻唑-6-基]苯基]-2-喹喔啉甲酰胺
SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.
价 格：￥电议型 号：T5096产 地：中国大陆
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T4S1725Galanthamine；加兰他敏Galantamine；Galantamine|||加兰他敏
Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.
价 格：￥电议型 号：T4S1725产 地：中国大陆
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T4999Ertugliflozin；埃格列净MK-8835|||PF-04971729；埃格列净|||MK-8835|||PF-04971729
PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).
价 格：￥电议型 号：T4999产 地：中国大陆
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T4547Grazoprevir；化合物GrazoprevirMK-5172；MK-5172
Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), 0.15 nM (gt2b), respectively.
价 格：￥电议型 号：T4547产 地：中国大陆
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T4172Methoxy-PMS；化合物1-Methoxy PMS1-Methoxyphenazine methosulfate|||1-Methoxy PMS；1-Methoxyphenazine metho
Methoxy-PMS (1-Methoxyphenazine methosulfate) is stable electron-transport mediator between NAD(P)H and tetrazolium dyes, can induce active oxygen formation.
价 格：￥电议型 号：T4172产 地：中国大陆
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T41172FAM-DEALA-Hyp-YIPD；FAM-DEALA-Hyp-YIPDFAM-DEALA-Hyp-YIPD
FAM-DEALA-Hyp-YIPD is a fluorescent HIF-1α peptide (Kd= 180-560 nM). Can be used to assess VHL binding in Fluorescence Polarization (FP) displacement assay, and evaluate the effect of VHL binding on degradation activity. Excitation maximum = 485 nm, emission maximum = 535 nm. Longer peptide version, FAM-DEALAHypYIPMDDDFQLRSF, also available.
价 格：￥电议型 号：T41172产 地：中国大陆
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T40172Iodoacetyl-PEG4-NHS ester；Iodoacetyl-PEG4-NHS esterIodoacetyl-PEG4-NHS ester；Iodoacetyl-PEG4-NHS est
Iodoacetyl-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T40172产 地：中国大陆
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T3S1729Dihydrolycorine；二氢石蒜碱Dihydrolycorine
1. Dihydrolycorine-HCL(DL) shows hypotensive effects, it can block alpha 1-adrenoceptors. 2. Dihydrolycorine is an inhibitors of protein synthesis in eukarytic cells, it halts protein synthesis in eukaryotic cells by inhibiting the peptide bone formation step. 3. Dihydrolycorine and nimodipine protects against anoxia damage of brain in rat.
价 格：￥电议型 号：T3S1729产 地：中国大陆
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T39927Zeteletinib hemiadipateZeteletinib hemiadipateBOS-172738 hemiadipate|||DS-5010hemiadipate|||Zeteleti
Zeteletinib hemiadipate (BOS-172738; DS-5010) is an orally active compound that functions as a selective inhibitor of RET kinase. It exhibits nanomolar potency against RET and a 300-fold selectivity towards VEGFR2. Notably, Zeteletinib hemiadipate demonstrates exceptional effectiveness against various forms of RET, including the wild type, RET V804M/L gatekeeper mutants, and the oncogenic RET mutation M918T. Additionally, Zeteletinib hemiadipate exerts potent antitumor effects.
价 格：￥电议型 号：T39927产 地：中国大陆
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T3961CYM-5541；化合物CYM 5541CYM 5541|||ML249|||CID-17253208；CYM 5541|||ML249|||CID-17253208
CYM-5541 (ML249) is a selective and allosteric S1P3 receptor agonist.
价 格：￥电议型 号：T3961产 地：中国大陆
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T39356PDD00017272；化合物 PDD00017272PDD-00017272；PDD-00017272
PDD00017272 (34f) is a potent inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with an EC50 value of 4.8 nM in biochemical assays and 9.2 nM in cellular POM.
价 格：￥电议型 号：T39356产 地：中国大陆
