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T65203Fmoc-Met-OPfp;化合物 Fmoc-Met-OPfpFmoc-Met-OPfp
Fmoc-Met-OPfp is a useful organic compound for research related to life sciences. The catalog number is T65203 and the CAS number is 86060-94-8.
价 格:¥电议型 号:T65203产 地:中国大陆
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T6513Bisindolylmaleimide I;化合物Bisindolylmaleimide IGF109203X|||Go 6850;GF109203X|||Go 6850|||3-[1-[3-(二甲氨
Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.
价 格:¥电议型 号:T6513产 地:中国大陆
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T64203T-Type calcium channel inhibitor 2;化合物 T-Type calcium channel inhibitor 2T-Type calcium channel inhi
T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, acting on Cav3.1 (α1G) (IC50: 31.0 μM), Cav3.2 (α1H) (IC50: 83.1 μM), Cav3.3 (α1I) (α1H) ( T-Type calcium channel inhibitor 2 exhibited cytotoxicity against A549 and HCT-116 cells with IC50s of 5.0 and 6.4 μM, respectively.
价 格:¥电议型 号:T64203产 地:中国大陆
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T63444UNC4203;化合物 UNC4203UNC4203
UNC4203 is a potent, highly selective, orally active MERTK inhibitor that acts on MERTK (IC50: 1.2 nM), AXL (IC50: 140 nM), TYRO3 (IC50: 42 nM) and FLT3 (IC50: 90 nM).
价 格:¥电议型 号:T63444产 地:中国大陆
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T63203GRK5-IN-4;化合物 GRK5-IN-4GRK5-IN-4
GRK5-IN-4 is a selective, potent, covalent GRK5 (G protein-coupled receptor kinase 5) inhibitor (IC50: 1.1 μM).GRK5-IN-4 is 90 times more selective for GRK5 than GRK2.GRK5-IN-4 can be used to study heart failure.
价 格:¥电议型 号:T63203产 地:中国大陆
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T62857K203;化合物 K203K203
K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.
价 格:¥电议型 号:T62857产 地:中国大陆
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T6265Bosentan (hydrate);波生坦水合物Bosentan Hydrate|||Benzenesulfonamide|||Actelion|||Ro 47-0203;波生坦水合物|||Bose
Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.
价 格:¥电议型 号:T6265产 地:中国大陆
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T6264Bosentan;波生坦Actelion|||Ro 47-0203|||Benzenesulfonamide;Actelion|||波生坦|||Ro 47-0203|||Benzenesulfonam
Bosentan (Benzenesulfonamide) is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and bronchoconstrictor, by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle. Bosentan decreases both pulmonary and systemic vascular resistance and is particul
价 格:¥电议型 号:T6264产 地:中国大陆
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T62203CDK9-IN-14;化合物 CDK9-IN-14CDK9-IN-14
CDK9-IN-14 is a potent, high and low selective CDK9 inhibitor (IC50: 6.92 nM). CDK9-IN-14 is a strong inhibitor of MV-4-11 cells and in vivo tumour models with low toxicity and few side effects.
价 格:¥电议型 号:T62203产 地:中国大陆
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T6203LSaxagliptin hydrochloride化合物 T6203LBMS477118|||Saxagliptin|||BMS 477118|||Saxagliptin HCl|||BMS-4771
Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fasting and postprandial glucose concentrations in a glucose-dependent manner in patients with type 2 diabetes mellitus.
价 格:¥电议型 号:T6203L产 地:中国大陆
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T62039L-365260 hemihydrate;化合物 L-365260 hemihydrateL-365260 hemihydrate
L-365260 hemihydrate is a selective, orally active non-peptide gastrin and brain cholecystokinin receptor (CCK-B) antagonist, demonstrating competitive interaction with guinea pig stomach gastrin and brain CCK receptors and exhibiting inhibition constants (Kis) of 1.9 nM and 2.0 nM, respectively.
价 格:¥电议型 号:T62039产 地:中国大陆
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T62038CDK2-IN-8;化合物 CDK2-IN-8CDK2-IN-8
CDK2-IN-8 is a potent CDK2 inhibitor (IC50= 1.74 μM). CDK2-IN-8 exhibits antiproliferative activity. CDK2-IN-8 can be used for the research of melanoma.
价 格:¥电议型 号:T62038产 地:中国大陆
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T62037BNS-22;化合物 BNS-22BNS-22
BNS-22 is a catalytic inhibitor of DNA topoisomerase II ( TOP2 ). BNS-22 shows the IC 50 values of 2.8 μM and 0.42 μM for human TOP2α and TOP2β, respectively. BNS-22 induces abnormal division and shows anti-proliferative activity.
价 格:¥电议型 号:T62037产 地:中国大陆
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T62036Sovesudil;化合物 SovesudilSovesudil
Sovesudil (PHP-201) is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor. Sovesudil shows IC50 s of 3.7 and 2.3 nM for ROCK-I and ROCK-II, respectively. Sovesudil can lower intraocular pressure (IOP) without inducing hyperemia.
价 格:¥电议型 号:T62036产 地:中国大陆
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T62035ATR-IN-7;化合物 ATR-IN-7ATR-IN-7
ATR-IN-7 is a potent inhibitor of ATR.
价 格:¥电议型 号:T62035产 地:中国大陆
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T62034DNA-PK-IN-7;化合物 DNA-PK-IN-7DNA-PK-IN-7
DNA-PK-IN-7 is a potent DNA-PK inhibitor (IC50= 1 nM) (WO2021104277A1, compound 5).
价 格:¥电议型 号:T62034产 地:中国大陆
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T62033Antitumor agent-65;化合物 Antitumor agent-65Antitumor agent-65
Antitumor agent-65 (Compound 5) is an analogue/derivative of (-)-cleistenolide. Antitumor agent-65 has potential in cancer research.
价 格:¥电议型 号:T62033产 地:中国大陆
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T62032SIRT5 inhibitor 2;化合物 SIRT5 inhibitor 2SIRT5 inhibitor 2
SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor (IC 50= 2.3 μM). SIRT5 inhibitor 2 shows inhibitory activity against the SIRT5-dependent desuccinylation. SIRT5 inhibitor 2 has research value in cancer and neurodegenerative diseases.
价 格:¥电议型 号:T62032产 地:中国大陆
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T62031SARS-CoV-2 nsp13-IN-4;化合物 SARS-CoV-2 nsp13-IN-4SARS-CoV-2 nsp13-IN-4
SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective small-molecule inhibitor of nsp13 helicase. SARS-CoV-2 nsp13-IN-4 inhibits the ssDNA+ ATPase activity of nsp13 with an IC 50 of 57 μM. SARS-CoV-2 nsp13-IN-4 can provide a broad-spectrum antiviral effect.
价 格:¥电议型 号:T62031产 地:中国大陆
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T62030BRD4-BD1-IN-1;化合物 BRD4-BD1-IN-1BRD4-BD1-IN-1
BRD4-BD1-IN-1 (Compound 9a) is a BRD4-BD1 inhibitor(IC50= 38.20 μM).
价 格:¥电议型 号:T62030产 地:中国大陆