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产品数:86101
参观次数:3709735
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T6S0221EriocitrinInhibitor,Eriocitrin,Apoptosis,inhibit
1. Eriocitrin is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress.(2) Lipid-lowering effects in a rat model of high-fat diet. 2. Dietary Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis. 3. Eriocitrin and Apigenin were identified as new potent inhibitors of human carbonic anhydrase VA isozyme.
价 格:¥电议型 号:T6S0221产 地:中国大陆
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T8572CL 218872GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Recep
CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α1, α2, α3, α4, α5 and α6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo.
价 格:¥电议型 号:T8572产 地:中国大陆
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T6587Mitiglinide CalciumS 21403,Potassium Channel,type,KAD 1229,Mitiglinide Calcium,diabetes,hypoglycaemi
Mitiglinide Calcium is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells.
价 格:¥电议型 号:T6587产 地:中国大陆
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T8921M-31850inhibit,M31850,OfHex2,M-31850,β-hexosaminidase,non-carbohydrate,Inhibitor,M 31850
M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor(human HexA and human HexB with IC50s of 6.0 μM and 3.1 μM, respectively). IT also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM.
价 格:¥电议型 号:T8921产 地:中国大陆
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T40187GNF2133β-cell,RIP-DTA mice,Inhibitor,insulin secretion,GNF2133,inhibit,Dual specificity tyrosine reg
GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.
价 格:¥电议型 号:T40187产 地:中国大陆
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T32191Irdabisant
Irdabisant (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant antagonist/inverse agonist of histamine H3 receptor (H3R) (rat H3R Ki= 7.2 nM, human H3R Ki= 2.0 nM). Irdabisant exhibits relatively low inhibitory activity against hERG current (IC50= 13.8 μM). Irdabisant exhibits cognition-enhancing and wake-promoting activities in the rat social recognition model. Irdabisant can be used for research on schizophrenia or cognitive impairment.
价 格:¥电议型 号:T32191产 地:中国大陆
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TN710313,21-DihydroeurycomanonePlasmodium,Toxoplasma,gondii,13,21-Dihydroeurycomanone,Inhibitor,inhibit,13
13,21-Dihydroeurycomanone is a natural product isolated from the root of Eurycoma longifolia with antiparasitic activity such as Plasmodium falciparum and Toxoplasma gondii.
价 格:¥电议型 号:TN7103产 地:中国大陆
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T64021GDC-6036-NH
GDC-6036-NH is a precursor compound for compound 17 a/b, derived from patent WO2020097537A2, where compound 17 a/b is a RAS inhibitor and can be used in cancer research.
价 格:¥电议型 号:T64021产 地:中国大陆
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T6546IPA-3inhibit,Inhibitor,IPA-3,p21 activated kinases,PAK
IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).
价 格:¥电议型 号:T6546产 地:中国大陆
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T21831UCM05
UCM05 (G28UCM) is a potent fatty acid synthase ( FASN ) inhibitor that shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines [1]. UCM05 is a Filamentous temperature-sensitive protein Z (FtsZ) inhibitor and inhibits the growth of the Gram-positive bacterium B. subtilis with MIC values of 100 μM but lack activity on the Gram-negative bacterium E. coli [2].
价 格:¥电议型 号:T21831产 地:中国大陆
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TN2159Robustinealkaloid,phosphodiesterase,Phosphodiesterase (PDE),Robustine,PDE5A,inhibit,Inhibitor
Robustine is a natural product, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro.
价 格:¥电议型 号:TN2159产 地:中国大陆
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T6950PNU-120596pain,NSC216666,anti-hyperalgesia,inhibit,inflammatory,PNU 120596,PNU-120596,Nicotinic acet
PNU-120596 is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.
价 格:¥电议型 号:T6950产 地:中国大陆
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TN2043Pasakbumin BPasakbumin B,Inhibitor,Eurycoma,antiulcer,inhibit,longifolia
Pasakbumin B is a bioactive compound from Eurycoma longifolia Jack.
价 格:¥电议型 号:TN2043产 地:中国大陆
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TP2167β-CGRP, human acetateβCGRP, human acetate,β CGRP, human acetate
β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptor (CRLR) (IC50s: 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells).
价 格:¥电议型 号:TP2167产 地:中国大陆
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T6854GSK621Apoptosis,CHOP,GSK 621,inhibit,AMP-activated protein kinase,Inhibitor,UPR,PERK,GSK621,Autophag
GSK621 is a specific and potent AMPK activator.
价 格:¥电议型 号:T6854产 地:中国大陆
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T6539Ibandronate sodium monohydrateInhibitor,BM210955,Ibandronate sodium monohydrate,inhibit,Apoptosis,BM
Ibandronate is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
价 格:¥电议型 号:T6539产 地:中国大陆
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TP1687LCEF20 acetate(153045-21-7 free base)CEF20 acetate(153045 21 7 free base),CEF-20 acetate(153045-21-7
CEF20 acetate is a CEF control peptide pool, is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503).
价 格:¥电议型 号:TP1687L产 地:中国大陆
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T7765E1210E-1210,Gwt1p,broad-spectrum,E1210,Glycosylphosphatidylinositol,inhibit,Fungal,disseminated,Inhi
E 1210 is broad-spectrum and orally active antifungal
价 格:¥电议型 号:T7765产 地:中国大陆
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T6840FRAX486PAK,p21 activated kinases,FRAX 486,Inhibitor,FRAX-486,inhibit,FRAX486
FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
价 格:¥电议型 号:T6840产 地:中国大陆