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T39044Rezvilutamide;瑞维鲁胺SHR3680;SHR3680
Rezvilutamide (SHR3680) is an orally available androgen receptor inhibitor that crosses the blood-brain barrier and has antitumor activity.Rezvilutamide (SHR3680) is used in the study of metastatic desmoplasia-resistant prostate cancer.
价 格:¥电议型 号:T39044产 地:中国大陆
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T39042Tarasaponin IV;Tarasaponin IVTarasaponin IV
Tarasaponin IV, an oleanane-type triterpene saponin, is derived from the bark of Aralia elata and holds potential for cancer research.
价 格:¥电议型 号:T39042产 地:中国大陆
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T39041Propanol-PEG4-CH2OH;Propanol-PEG4-CH2OHPropanol-PEG4-CH2OH;Propanol-PEG4-CH2OH
Propanol-PEG4-CH2OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39041产 地:中国大陆
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T3904Gomisin J;戈米辛JGomisin J
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca2+/calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells.
价 格:¥电议型 号:T3904产 地:中国大陆
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T39039FSCPX;化合物FSCPXFSCPX
FSCPX is a potent and selective irreversible antagonist of the A1 adenosine receptor (A1AR), exhibiting low nanomolar binding potency. Additionally, FSCPX can effectively decrease the interstitial adenosine level in the guinea pig atrium, thereby modifying the effect of NBTI, a nucleoside transport inhibitor.
价 格:¥电议型 号:T39039产 地:中国大陆
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T39038RORγt inhibitor 1;RORγt inhibitor 1RORγt inhibitor 1
RORγt inhibitor 1 is a RORγt allosteric inhibitor with an IC 50 value of 1 nM.
价 格:¥电议型 号:T39038产 地:中国大陆
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T39037Tiludronate disodium hemihydrate;替鲁膦酸二钠半水合物Tiludronic acid disodium hemihydrate;Tiludronic acid diso
Tiludronate (Tiludronic Acid) disodium hemihydrate is an orally active bisphosphonate compound that functions as an osteoregulator. It is primarily utilized in metabolic bone disorder research. This compound acts as a potent inhibitor of the osteoclast vacuolar H+ -ATPase and possesses antiresorptive and anti-inflammatory properties[4].
价 格:¥电议型 号:T39037产 地:中国大陆
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T39036(3R,5S)-Fluvastatin;(3R,5S)-Fluvastatin(3R,5S)-Fluvastatin|||(3R,5S)-XU 62-320 free acid;(3R,5S)-Flu
(3R,5S)-Fluvastatin, the 3R,5S-isomer of Fluvastatin (XU 62-320 free acid), stands as the inaugural fully synthetic, competitive inhibitor of HMG-CoA reductase, exhibiting an IC50 value of 8 nM. It safeguards vascular smooth muscle cells from oxidative stress by activating the Nrf2-dependent antioxidant pathway.
价 格:¥电议型 号:T39036产 地:中国大陆
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T39035FXIa-IN-6;FXIa-IN-6FXIa-IN-6
FXIa-IN-6 is a potent FXIa inhibitor with selectivity against most of the relevant serine proteases ( K i = 0.3 nM). FXIa-IN-6 also demonstrated excellent pharmacokinetics (PK) profile (high oral bioavailability and low clearance) in multiple preclinical species.
价 格:¥电议型 号:T39035产 地:中国大陆
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T39034PEG2-ethyl acetate;PEG2-ethyl acetatePEG2-ethyl acetate;PEG2-ethyl acetate
PEG2-ethyl acetate is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39034产 地:中国大陆
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T39033Pomalidomide-6-O-CH3;Pomalidomide-6-O-CH3Pomalidomide-6-O-CH3;Pomalidomide-6-O-CH3
Pomalidomide-6-O-CH3 is a Pomalidomide-derived ligand for cereblon (CRBN), which serves as a linkage agent to recruit the CRBN protein. This ligand, when connected to a protein via a linker, enables the formation of PROTAC.
价 格:¥电议型 号:T39033产 地:中国大陆
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T39032Pomalidomide-5-O-CH3;Pomalidomide-5-O-CH3Pomalidomide-5-O-CH3;Pomalidomide-5-O-CH3
Pomalidomide-5-O-CH3, a derivative of Pomalidomide, serves as a specific ligand for cereblon (CRBN) protein recruitment. It can be linked to the protein ligand to create a PROTAC.
价 格:¥电议型 号:T39032产 地:中国大陆
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T39031Olmesartan impurity;Olmesartan impurityOlmesartan impurity
Olmesartan impurity, a compound related to Olmesartan, is an angiotensin II receptor (AT1R) antagonist utilized in the study of high blood pressure. Olmesartan (RNH-6270) is the parent compound with similar properties and functions as an AT1R antagonist.
价 格:¥电议型 号:T39031产 地:中国大陆
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T39030HBDDE;化合物HBDDEHBDDE
HBDDE is a selective model inhibitor of the isoenzymes PKCα and PKCγ with IC 50 s of 43 μM and 50 μM, respectively.HBDDE has a higher affinity for PKCα/PKCγ than the PKCδ, PKCβI, and PKCβII isoenzymes.HBDDE is a derivative of ellagic acid, which induces apoptosis in neuronal cells. HBDDE is a derivative of ellagic acid and induces apoptosis in neuronal cells.
价 格:¥电议型 号:T39030产 地:中国大陆
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T3903Angoroside C安格洛甙C安格洛甙C|||安格洛苷C
Angoroside C is a Potential anti-inflammatory compound. Inhibitor of prostaglandin E2 release in mouse peritoneal macrophages in vitro. Shows potent antioxidative activity in reducing the oxidized OH adducts of dAMP and dGMP. Reveals some trypanocidal potential.
价 格:¥电议型 号:T3903产 地:中国大陆
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T39029APC-6860;APC-6860APC-6860
APC-6860 is a trypsin-like serine proteases inhibitor with k i values of 0.21, 0.44, 1.5, 16.8, 20, 30 μM for uPA, trypsin, tryptase, tPA, thrombin and factor Xa, respectively. APC-6860 has a selectivity ratio for tPA versus uPA of 80. APC-6860 has k i values of 0.1, 0.082 μM for human and murine urokinases, respectively. APC-6860 can be used for the research of cancer.
价 格:¥电议型 号:T39029产 地:中国大陆
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T39028Prunetrin;PrunetrinPrunetin4′-O-β-D-glucopyranoside|||Trifoside;Prunetin4′-O-β-D-glucopyranoside|||T
Prunetrin (Trifoside), a soflavonoid, is present in both the aerial and subterranean parts of red clover.
价 格:¥电议型 号:T39028产 地:中国大陆
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T39027PKH 26;PKH 26PKH 26
PKH 26, a red-fluorescent lipophilic membrane dye (Ex/Em=551/567nm), is extensively utilized for assessing cell proliferation in heterogeneous cell populations through flow cytometry.
价 格:¥电议型 号:T39027产 地:中国大陆
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T39026Ni(II) protoporphyrin IX;Ni(II) protoporphyrin IXNi(II) protoporphyrin IX
Ni(II) protoporphyrin IX is a metalloporphyrin compound characterized by its limited propensity for axial ligation and its distortion upon binding to ferrochelatase.
价 格:¥电议型 号:T39026产 地:中国大陆
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T39023Biotin-sar-oh;Biotin-sar-ohBiotin sar oh|||Biotinsaroh|||Biotin-sar-oh;Biotin sar oh|||Biotinsaroh||
Biotin-sar-oh is a cleavable linker vital in ADC synthesis. Biotin-sar-oh joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格:¥电议型 号:T39023产 地:中国大陆