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  • T40549PPA；PPAPPA

    PPA serves as an ADC linker (US20060073528A1), facilitating the production of antibody-drug conjugates.

    价 格：￥电议型 号：T40549产 地：中国大陆

  • T40548NH-3；化合物NH-3NH-3

    NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the binding of thyroid hormones to their respective receptors, resulting in hindered cofactor recruitment.

    价 格：￥电议型 号：T40548产 地：中国大陆

  • T40547Lenalidomide-4-aminomethyl hydrochloride；Lenalidomide-4-aminomethyl hydrochlorideLenalidomide-4-amin

    Lenalidomide-4-aminomethyl hydrochloride is a compound derived from Lenalidomide, serving as a cereblon (CRBN) ligand for the recruitment of CRBN protein. By connecting Lenalidomide-4-aminomethyl hydrochloride to the ligand via a linker, PROTAC formation can be facilitated.

    价 格：￥电议型 号：T40547产 地：中国大陆

  • T405463-Methylthienyl-carbonyl-JNJ-7706621；3-Methylthienyl-carbonyl-JNJ-77066213-Methylthienyl-carbonyl-JN

    3-Methylthienyl-carbonyl-JNJ-7706621 is a highly potent and selective inhibitor of cyclin-dependent kinase (CDK). It exhibits impressive IC50 values of 6.4 nM and 2 nM for CDK1/cyclin B and CDK2/cyclin A, respectively. Additionally, 3-Methylthienyl-carbonyl-JNJ-7706621 demonstrates potent inhibition against GSK-3 (IC50 = 0.041 μM) and moderate potency towards CDK4, VEGF-R2, and FGF-R2 (IC50 = 0.11 μM, 0.13 μM, and 0.22 μM, respectively). Its applications in cancer research are noteworthy.

    价 格：￥电议型 号：T40546产 地：中国大陆

  • T40545MES；2-吗啉乙磺酸(MES)2-Morpholinoethanesulphonic acid|||4-Morpholineethanesulfonic acid；2-Morpholinoethan

    MES (2-Morpholinoethanesulphonic acid) (2-Morpholinoethanesulphonic acid), a zwitterionic buffer, is effective in the pH range of 5.5-7.7. MES, as one of the Good’s buffers, is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments.

    价 格：￥电议型 号：T40545产 地：中国大陆

  • T40544NCGC00092410；化合物NCGC00092410ML008；ML008

    NCGC00092410 (ML008) is a glucocerebrosidase (GC) inhibitor with IC50 value of 31 nM. It can be used for the study of Gaucher disease caused by mutation of glucocerebrase gene.

    价 格：￥电议型 号：T40544产 地：中国大陆

  • T405433-Furanmethanol；3-呋喃甲醇3-Furanmethanol

    3-Furanmethanol is a furan compound exhibiting diverse sensory properties. Efficient and highly regioselective photocycloaddition reactions occur between 3-Furanmethanol and 2-cyanonaphthalenes.

    价 格：￥电议型 号：T40543产 地：中国大陆

  • T40542Sinbaglustat；化合物SinbaglustatACT-519276|||Sinbaglustat|||OGT2378；ACT-519276|||Sinbaglustat|||OGT2378

    Sinbaglustat (OGT2378) (OGT2378) is a dual inhibitor of glucose ceramide synthetase (GCS) and non-lysosomal glucose ceramidase (GBA2).Sinbaglustat is an orally administered N-alkyl iminosugar that crosses the blood-brain barrier.Sinbaglustat is used for the treatment of lysosomal storage disorders and for the study of central neurodegenerative disorders associated with lysosomal dysfunction. Sinbaglustat is used for the treatment of lysosomal storage disorders and for the study of lysosomal dysf

    价 格：￥电议型 号：T40542产 地：中国大陆

  • T40541α-Synuclein (61-75)；α-Synuclein (61-75)α-Synuclein (61-75)

    α-Synuclein (61-75) is a peptide fragment derived from the larger protein α-Synuclein. α-Synuclein is predominantly found in presynaptic nerve terminals and is considered to be a biomarker candidate for Parkinson´s disease (PD).

    价 格：￥电议型 号：T40541产 地：中国大陆

  • T40540Bis-PEG6-t-butyl ester；Bis-PEG6-t-butyl esterBis-PEG6-t-butyl ester；Bis-PEG6-t-butyl ester

    Bis-PEG6-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T40540产 地：中国大陆

  • T4054Dantrolene sodium hemiheptahydrate；丹曲林钠五水合物Dantrolene sodium hydrate|||Dantrolene sodium salt|||Dant

    Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from the sarcoplasmic reticulum, an essential step in muscle contraction. Dantrolene sodium hemiheptahydrate (Sodium dantrolene) is the sodium salt form of dantrolene, a hydantoin derivative, and direct-acting skeletal muscle relaxant.

    价 格：￥电议型 号：T4054产 地：中国大陆

  • T40537Ibuprofen Impurity K；Ibuprofen Impurity KIbuprofen Impurity K

    Ibuprofen Impurity K is a compound that serves as an impurity in Ibuprofen. Ibuprofen itself is an anti-inflammatory inhibitor specifically designed to target COX-1 and COX-2. It exhibits inhibitory activity with IC50 values of 13 μM and 370 μM for COX-1 and COX-2, respectively.

    价 格：￥电议型 号：T40537产 地：中国大陆

  • T40536[Glu4]-Oxytocin；[Glu4]-Oxytocin[Glu4]-Oxytocin|||[Glu4] Oxytocin|||[Glu4]Oxytocin|||[Glu4]-Oxytocin|

    [Glu4]-Oxytocin is a suitable derivative of oxytocin for conducting a thorough investigation, utilizing various methods, into the conformation of "oxytocin-like" molecules in aqueous solution.

    价 格：￥电议型 号：T40536产 地：中国大陆

  • T40534[Leu3]-Oxytocin；[Leu3]-Oxytocin[Leu3]-Oxytocin；[Leu3]-Oxytocin

    [Leu3]-Oxytocin, an oxytocin analogue, is a derivative of oxytocin wherein the leucine amino acid (Leu) has been substituted at the 3rd position in the sequence.

    价 格：￥电议型 号：T40534产 地：中国大陆

  • T40533THP-PEG10-THP；THP-PEG10-THPTHP-PEG10-THP；THP-PEG10-THP

    THP-PEG10-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T40533产 地：中国大陆

  • T40532MS-PEG10-THP；MS-PEG10-THPMS-PEG10-THP；MS-PEG10-THP

    MS-PEG10-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T40532产 地：中国大陆

  • T40531THP-PEG10-OH；THP-PEG10-OHTHP-PEG10-OH；THP-PEG10-OH

    THP-PEG10-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T40531产 地：中国大陆

  • T40530Ms-PEG6-THP；Ms-PEG6-THPMs-PEG6-THP；Ms-PEG6-THP

    Ms-PEG6-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T40530产 地：中国大陆

  • T4053AST 487；化合物AST 487NVP-AST 487；NVP-AST 487

    AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.

    价 格：￥电议型 号：T4053产 地：中国大陆

  • T40529(R)-(-)-1,2-Propanediol；(R)-(-)-1,2-丙二醇(R)-(-)-1,2-Propanediol

    (R)-(-)-1,2-Propanediol is the (R)-enantiomer of 1,2-Propanediol, which is derived from glucose through the expression of NADH-linked glycerol dehydrogenase genes in Escherichia coli.

    价 格：￥电议型 号：T40529产 地：中国大陆

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