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T6513Bisindolylmaleimide IGo6850,Bisindolylmaleimide I,PKC,Protein kinase C,Go-6850,inhibit,Inhibitor
GF109203X is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.
价 格:¥电议型 号:T6513产 地:中国大陆
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T6651Safinamide mesylateEMD 1195686,Monoamine Oxidase,EMD-1195686,neuroprotective,inhibit,OGD/R,Glucose,n
Safinamide Mesylate, a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.
价 格:¥电议型 号:T6651产 地:中国大陆
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T6400AZD3514selective,anti proliferation,LAPC4,Inhibitor,AZD3514,AZD-3514,oral,AZD 3514,rat,AR protein,pr
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
价 格:¥电议型 号:T6400产 地:中国大陆
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T6519GramineGramine,Adrenergic Receptor,AdipoRs,Reverse Transcriptase,Inhibitor,Adiponectin Receptor,Beta
Gramine, a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist. Gramine has anti-tumor, anti-viral and anti-inflammatory properties.
价 格:¥电议型 号:T6519产 地:中国大陆
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T64320ML251cruzi,inhibit,brucei,MRC-5,Inhibitor,nanomolar,Parasite,ML-251,ML 251,ML251
ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase[1]. ML251 inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1].
价 格:¥电议型 号:T64320产 地:中国大陆
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T9251Fedratinib hydrochloride hydrateSTAT5,JAK2V617F,myeloproliferative,TG-101348 hydrochloride,Janus kin
Fedratinib hydrochloride hydrate is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.
价 格:¥电议型 号:T9251产 地:中国大陆
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T6515Go6976Go6976,Influenza Virus,arrest,inhibit,Go 6976,Protein kinase C,Go-6976,cell,PKC,Inhibitor
Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3.
价 格:¥电议型 号:T6515产 地:中国大陆
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T15190L(S,R,S)-AHPC-PEG4-NH2
(S,R,S)-AHPC-PEG4-NH2 is a synthetic E3 ligase ligand-linker conjugate comprising a VHL ligand based on (S,R,S)-AHPC and a 4-unit PEG linker.
价 格:¥电议型 号:T15190L产 地:中国大陆
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T7416WS-12HEK293T,AVX 012,chronic neuropathic pain,TRP Channel,AR 15512,inhibit,AVX012,WS 12,WS12,WS-12,A
WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)
价 格:¥电议型 号:T7416产 地:中国大陆
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TP1672LN-Formyl-Met-Ala-Ser TFA(17351-32-5 free base)N Formyl Met Ala Ser TFA(17351 32 5 free base),NFormyl
N-Formyl-Met-Ala-Ser TFA is a peptide, binds to formyl peptide receptors on neutrophils.N-Formyl-Met-Ala-Ser Peptide (fMet-Ala-Ser) binds to formyl peptide receptors on neutrophils. N-Formylmethionine-containing peptides including the most potent and known member, N-formyl-Met-Leu-Phe (FMLP or fMet-Leu-Phe) stimulate human neutrophils by a receptor-dependent mechanism.
价 格:¥电议型 号:TP1672L产 地:中国大陆
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T15117Didesmethyl cariprazineDidesmethyl cariprazine
Cariprazine is an antipsychotic drug candidate. It shows high affinity for the D3 and D2 receptors, and moderate affinity for the 5-HT1A receptor. Didesmethyl cariprazine is a metabolite of Cariprazine and acts as the predominant circulating active moiety.
价 格:¥电议型 号:T15117产 地:中国大陆
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T8779HBT1HBT 1,Ionotropic glutamate receptors,HBT-1,BDNF,LBD,inhibit,glutamate,AMPA,primary neurons,S518,
HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner.
价 格:¥电议型 号:T8779产 地:中国大陆
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T8511TM38837peripheral,Cannabinoid Receptor,TM-38837,CB1,antiobesity,TM38837,inhibit,fat,TM 38837,Inhibit
TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.
价 格:¥电议型 号:T8511产 地:中国大陆
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T7610GW284543Inhibitor,inhibit,GW 284543,GW284543,UNC 10225170,MIA PaCa-2,GW-284543,Mitogen-activated pro
GW284543 is a selective inhibitor of MEK5 .
价 格:¥电议型 号:T7610产 地:中国大陆
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T6351MGCD-265 analogGlesatinib;MGCD-265
MGCD-265-analog (structurally related to MGCD-265) is an orally bioavailable multitargeted tyrosine kinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively.
价 格:¥电议型 号:T6351产 地:中国大陆
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T6337RepSoxALK5 Inhibitor II;SJN 2511;E-616452
RepSox is a potent and selective of the TGFβR-1/ALK5 inhibitor.
价 格:¥电议型 号:T6337产 地:中国大陆
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T6325PCI-34051N-羟基-1-(4-甲氧基苄基)-1H-吲哚-6-甲酰胺;PCI 34051;PCI34051
PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).
价 格:¥电议型 号:T6325产 地:中国大陆
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T6251PF-04691502PF4691502;PF 04691502
PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.
价 格:¥电议型 号:T6251产 地:中国大陆
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T6226Pemetrexed disodium hemipenta hydratePemetrexed Disodium Hydrate;Pemetrexed sodium hydrate;LY-231514
Pemetrexed Disodium Hydrate is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 65 nM, respectively.
价 格:¥电议型 号:T6226产 地:中国大陆
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T6205AT7519
AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.
价 格:¥电议型 号:T6205产 地:中国大陆