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T9996NCT-58
NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR). NCT-58 elicits anti-tumor activity via the simultaneous downregulation of HER family members as well as inhibition of Akt phosphorylation. NCT-58 kills Trastuzumab-resistant breast cancer stem-like cells. NCT-58 induces apoptosis in HER2-positive breast cancer cells.
价 格：￥电议型 号：T9996产 地：中国大陆
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T11458GPR40/FFAR1 modulator 1GPR40/FFAR1 modulator 1,Free Fatty Acid Receptor,inhibit,GPR-40/FFAR1 modulat
GPR40/FFAR1 modulator 1 is an agonist and an allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1).
价 格：￥电议型 号：T11458产 地：中国大陆
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TP1858LPhe-Met-Arg-Phe, amide acetatePhe Met Arg Phe, amide acetate,PheMetArgPhe, amide acetate
Phe-Met-Arg-Phe, amide acetate dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons. This peptide appears to localize with neuropeptide Y in some regions of the brain.
价 格：￥电议型 号：TP1858L产 地：中国大陆
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TN5891SeselinSeselin
Seselin is a natural product from Plumbago zeylanica. Seselin shows anti-inflammatory and antiviral activity.
价 格：￥电议型 号：TN5891产 地：中国大陆
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Fr13587Compound Fr13587Compound Fr13587
7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. It exhibited either alone or as hybrid with other active pharmacophores diverse pharmacological profiles. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake ( IC 50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC 50 s of 1.18 μM and 0.97 μM, respectively [1].
价 格：￥电议型 号：Fr13587产 地：中国大陆
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T2058PalosuranACT058362,urotensin,Palosuran,Inhibitor,ischemia,diabetic,UT receptor,reperfusion,Urotensin
Palosuran (ACT-058362) is a new potent and specific antagonist of the human UT receptor.
价 格：￥电议型 号：T2058产 地：中国大陆
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T6895TAK-580BIIB024,TAK-580,Raf kinases,inhibit,MLN-2480,TAK580,BIIB 024,TAK 580,Raf,Inhibitor,MLN 2480
MLN2480 is an oral, selective pan-Raf kinase inhibitor in Clinicalal trials.
价 格：￥电议型 号：T6895产 地：中国大陆
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T9558KL-11743GLUT,inhibit,KL11743,Inhibitor,KL 11743,GLUT1,GLUT2,KL-11743,GLUT3,glucose,GLUT4,Glucose tra
KL-11743 specifically blocks glucose metabolism, triggering an acute collapse in NADH pools and a striking accumulation of aspartate, indicating a dramatic shift toward oxidative phosphorylation in the mitochondria.
价 格：￥电议型 号：T9558产 地：中国大陆
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T25867Nicodan Percutan
Nicodan Percutan is the propyl ester form of niacin, which is found in various animal and plant tissues to form the coenzymes NAD and NADP.
价 格：￥电议型 号：T25867产 地：中国大陆
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TP1101Nonapeptide-1 acetate salt (158563-45-2 free base)Nonapeptide1 acetate salt (158563452 free base),No
Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Nonapeptide-1 acetate salt Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM.
价 格：￥电议型 号：TP1101产 地：中国大陆
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TP2068LCyclotraxin B acetate(1203586-72-4 free base)Cyclotraxin B acetate(1203586 72 4 free base),Cyclotrax
Cyclotraxin B acetate is an antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also shown to exhibit putative anxiolytic properties in mice.
价 格：￥电议型 号：TP2068L产 地：中国大陆
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T9588JI130JI130,JI-130
JI130 is able to impair the ability of Hes1 to repress transcription. JI130 treatment significantly reduced tumor volume in a murine pancreatic tumor xenograft model.
价 格：￥电议型 号：T9588产 地：中国大陆
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TQ0058MI-463MI463,Epigenetic Reader Domain,MI-463,MI 463,Inhibitor,inhibit
MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).
价 格：￥电议型 号：TQ0058产 地：中国大陆
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T7588LefamulinLefamulin
Lefamulin is a semi-synthetic compound that inhibits the synthesis of bacterial protein, which is required for bacteria to grow.
价 格：￥电议型 号：T7588产 地：中国大陆
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T35899JAK1-IN-8JAK1IN8,JAK-1-IN-8,JAK1 IN 8
JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
价 格：￥电议型 号：T35899产 地：中国大陆
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T21858Arcyriaflavin AArcyriaflavin A
Arcyriaflavin A is a metabolite obtained from the fungi, Nocardiopsis sp.
价 格：￥电议型 号：T21858产 地：中国大陆
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T7958Methyl arachidateLTA4H,natural,Methyl arachidate,Aminopeptidase,inhibit,Inhibitor,compound,Methyl ei
Methyl Icosanoate is an esterified form of arachidic acid
价 格：￥电议型 号：T7958产 地：中国大陆
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T6289DovitinibCHIR-258；TKI258；多韦替尼；度维替尼
Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to EGFR, InsR, EphA2, c-Met, IGF-1R, Tie2, and HER
价 格：￥电议型 号：T6289产 地：中国大陆
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T6271TipifarnibZarnestra；IND 58359；R115777；替吡法尼
Tipifarnib is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting
价 格：￥电议型 号：T6271产 地：中国大陆
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T6258ZibotentanZD4054
Zibotentan (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.
价 格：￥电议型 号：T6258产 地：中国大陆
