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T62106(Rac)-ErSO-DFP;化合物 (Rac)-ErSO-DFP(Rac)-ErSO-DFP
(Rac)-ErSO-DFP is a derivative of ErSO-DFP and a selective small molecule Erα biomodulator. (Rac)-ErSO-DFP overactivates ERα+-dependent anticipatory unfolded protein responses and exhibits anti-estrogen receptor alpha-positive breast cancer, including its resistant tumours.
价 格:¥电议型 号:T62106产 地:中国大陆
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T62105NT219;化合物 NT219NT-219;NT-219
NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3, enhances the aggregation of misfolded prion protein NT219 affects the levels of certain molecular chaperones and inhibits STAT3 phosphorylation NT219 is useful for the study of cancer and neurodegenerative diseases.
价 格:¥电议型 号:T62105产 地:中国大陆
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T62104NS2B/NS3-IN-5;化合物 NS2B/NS3-IN-5NS2B/NS3-IN-5
NS2B/NS3-IN-5 (Compound 25b) is a variant of the DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.67 μM and 4.38 μM for the NS2B/NS3 protease of ZIKV and DENV2, respectively.
价 格:¥电议型 号:T62104产 地:中国大陆
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T62103COX-2/PI3K-IN-1;化合物 COX-2/PI3K-IN-1COX-2/PI3K-IN-1
COX-2/PI3K-IN-1 (compound 5d) is a potent inhibitor of PI3K (IC50: 1.14 nM). COX-2/PI3K-IN-1 is a selective inhibitor of COX-2 (Ki: 3.24 nM).
价 格:¥电议型 号:T62103产 地:中国大陆
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T62101hCAXII-IN-2;化合物 hCAXII-IN-2hCAXII-IN-2
hCAXII-IN-2 (compound 5i) is a potent inhibitor of human carbonic anhydrase XII (hCA XII) (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity against hCA I and hCA II.
价 格:¥电议型 号:T62101产 地:中国大陆
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T62100MAT2A-IN-6;化合物 MAT2A-IN-6MAT2A-IN-6
MAT2A-IN-6 is a potent inhibitor of MAT2A. MAT2A-IN-6 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-6 has shown potential research value in cancer diseases.
价 格:¥电议型 号:T62100产 地:中国大陆
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T6210Pifithrin-μ;化合物Pifithrin-μPFTμ|||NSC 303580|||2-Phenylethynesulfonamide;PFTμ|||NSC 303580|||2-Phenyl
Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.
价 格:¥电议型 号:T6210产 地:中国大陆
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T61898RS6212;化合物 RS6212RS6212
RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M)。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.
价 格:¥电议型 号:T61898产 地:中国大陆
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T61621IMMH001;化合物 IMMH001IMMH001
IMMH001, also known as SYL930, is an orally active compound that exhibits potent selectivity as an agonist for the S1P1 receptor, which is the sphingosine-1-phosphate receptor 1. This compound effectively reduces the levels of various chemokines and proinflammatory cytokines, such as IL-1β, IL-5, IL-18, IP10, CCL3, and CCL5. IMMH001 finds utility in research focused on rheumatoid arthritis (RA) [1] [2].
价 格:¥电议型 号:T61621产 地:中国大陆
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T6126JNJ-7706621;化合物JNJ7706621JNJ 7706621;JNJ 7706621
JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.
价 格:¥电议型 号:T6126产 地:中国大陆
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T60621PFM03;化合物 PFM03PFM03
PFM03 is an inhibitor of MRE11 Endonuclease that regulates DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) [1].
价 格:¥电议型 号:T60621产 地:中国大陆
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T60018NSC 694621;化合物 NSC 694621NSC 694621
NSC 694621 is a potent PCAF inhibitor with an IC 50 of 5.71 μM ( PCAF/H3 1-21 ). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells that has the potential to be the new anticancer agent[1].
价 格:¥电议型 号:T60018产 地:中国大陆
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T60016VV116;化合物 VV116GS-621763-d1|||JT001;GS-621763-d1|||JT001
VV116 (JT001) is a selective and orally active nucleoside antiviral agent against respiratory syncytial virus (RSV) and SARS-CoV-2 infection.
价 格:¥电议型 号:T60016产 地:中国大陆
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T5621β-Phellandrene;3-异丙基-6-亚甲基-1-环己烯beta-Phellandrene|||p-mentha-1(7),2-diene;beta-Phellandrene|||3-异丙基-
β-Phellandrene (p-mentha-1(7),2-diene) is found in allspice. beta-Phellandrene is widely distributed in essential oils
价 格:¥电议型 号:T5621产 地:中国大陆
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T5099Gefapixant;化合物GefapixantRO 4926219|||AF219|||MK-7264;RO 4926219|||AF219|||MK-7264
Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.
价 格:¥电议型 号:T5099产 地:中国大陆
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T40621Bis(2-bromoethyl) ether;Bis(2-bromoethyl) etherBis(2-bromoethyl) ether
Bis2-bromoethyl ether is an alkyl chain-derived PROTAC linker, facilitating the synthesis of PROTACs.
价 格:¥电议型 号:T40621产 地:中国大陆
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T405463-Methylthienyl-carbonyl-JNJ-7706621;3-Methylthienyl-carbonyl-JNJ-77066213-Methylthienyl-carbonyl-JN
3-Methylthienyl-carbonyl-JNJ-7706621 is a highly potent and selective inhibitor of cyclin-dependent kinase (CDK). It exhibits impressive IC50 values of 6.4 nM and 2 nM for CDK1/cyclin B and CDK2/cyclin A, respectively. Additionally, 3-Methylthienyl-carbonyl-JNJ-7706621 demonstrates potent inhibition against GSK-3 (IC50 = 0.041 μM) and moderate potency towards CDK4, VEGF-R2, and FGF-R2 (IC50 = 0.11 μM, 0.13 μM, and 0.22 μM, respectively). Its applications in cancer research are noteworthy.
价 格:¥电议型 号:T40546产 地:中国大陆
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T40276GS-621763;化合物GS-621763GS-621763
GS-621763, a prodrug of GS-441524, exhibits antiviral activity against SARS-CoV-2 pathogenesis.
价 格:¥电议型 号:T40276产 地:中国大陆
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T39621Bromo-PEG2-NHS ester;Bromo-PEG2-NHS esterBromo-PEG2-NHS ester;Bromo-PEG2-NHS ester
Bromo-PEG2-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39621产 地:中国大陆
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T37621Ezeprogind disulfate;化合物Ezeprogind disulfateEzeprogind disulfate
Ezeprogind disulfate is a neurotrophic inducer. Ezeprogind disulfate targets all causes of neurodegeneration including Abeta protein or tau protein. Ezeprogind disulfate can be used for the research of neurological disorders, including progressive supranu
价 格:¥电议型 号:T37621产 地:中国大陆