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T62912PI3K/HDAC-IN-2;化合物 PI3K/HDAC-IN-2PI3K/HDAC-IN-2
PI3K/HDAC-IN-2 is a potent dual PI3K/HDAC inhibitor, capable of acting on PI3Kα (IC50: 226 nM), PI3Kβ (IC50: 279 nM), PI3Kγ (IC50: 467 nM), PI3Kδ (IC50: 29 nM), HDAC1 (IC50: 1.3 nM), and PI3K/HDAC-IN-2 is PI3Kδ and class I and IIb HDAC selective and exhibits significant anticancer effects.
价 格:¥电议型 号:T62912产 地:中国大陆
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T62911Dalmelitinib;化合物 DalmelitinibDalmelitinib
Dalmelitinib is a selective, orally active c-Met kinase inhibitor (IC50: 2.9 nM) that binds the ATP-binding region of c-Met. Dalmelitinib induces phosphorylation of MET and partially or completely inhibits phosphorylation of AKT and ERK. dalmelitinib exhibits a potent inhibitory effect on the proliferation of cancer cells (c-Met oncogene amplification) and can be used in cancer research (e.g. non-small cell lung cancer).
价 格:¥电议型 号:T62911产 地:中国大陆
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T62910Antibacterial agent 62;化合物 Antibacterial agent 62Antibacterial agent 62
Antibacterial agent 62 is a novel redox cycle anti-tuberculosis compound that exhibits significant bactericidal activity against growth and nutrient deficient phenotypically resistant non-growing bacteria.
价 格:¥电议型 号:T62910产 地:中国大陆
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T6291WZ4003;化合物WZ4003WZ4003
WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively. It is no significant inhibition on 139 other kinases.
价 格:¥电议型 号:T6291产 地:中国大陆
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T62909SGC agonist 2;化合物 SGC agonist 2SGC agonist 2
SGC agonist 2 is a potent soluble guanylate cyclase (SGC) agonist. SGC agonist 2 has potential for cardiovascular disease (heart failure, angina, pulmonary hypertension, myocardial infarction) and fibrotic disease (renal fibrosis, systemic sclerosis).
价 格:¥电议型 号:T62909产 地:中国大陆
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T62908DENV-IN-6;化合物 DENV-IN-6DENV-IN-6
DENV-IN-6 is a potent inhibitor of DENV (I-IV), demonstrating EC50 values of 17.5, 13.20, 6.8, and 11.41 μM for the inhibition of DENV (I-IV) replication, respectively. Additionally, it exhibits anti-HIV-1 IIIB activity, with an EC50 of 0.0181 ?M and a CC50 of 64.92 ?M [1].
价 格:¥电议型 号:T62908产 地:中国大陆
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T62907TAS-117 hydrochloride;化合物 TAS-117 hydrochlorideTAS-117 hydrochloride
TAS-117 hydrochloride is a selective, potent, orally active allosteric Akt inhibitor, acting on Akt1 (IC50: 4.8 nM), Akt2 (IC50: 1.6 nM) and Akt3 (IC50: 44 nM). TAS-117 hydrochloride stimulates anti-myeloma activity, enhances lethal endoplasmic reticulum stress induced by proteasome inhibition, and can induce apoptosis and autophagy.
价 格:¥电议型 号:T62907产 地:中国大陆
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T62906Lazuvapagon;化合物 LazuvapagonLazuvapagon
Lazuvapagon is a vasopressin V2 receptor agonist that can be used to study enuresis.
价 格:¥电议型 号:T62906产 地:中国大陆
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T62905GLS-1-IN-1;化合物 GLS-1-IN-1GLS-1-IN-1
GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.
价 格:¥电议型 号:T62905产 地:中国大陆
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T62904PknB-IN-2;化合物 PknB-IN-2PknB-IN-2
PknB-IN-2 (Compound 10) is an inhibitor of Mycobacterium tuberculosis protein kinase B (PknB) (IC50: 12.1 μM).
价 格:¥电议型 号:T62904产 地:中国大陆
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T62903Enpp-1-IN-6;化合物 Enpp-1-IN-6Enpp-1-IN-6
Enpp-1-IN-6 is a potent inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1). Enpp-1-IN-6 has the potential to be used in cancer and infectious disease research.
价 格:¥电议型 号:T62903产 地:中国大陆
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T62902NDI-034858;化合物NDI-034858TAK-279|||NDI-03485;TAK-279|||NDI-03485
NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseases caused by aberrant expression of IL12 and IL23.
价 格:¥电议型 号:T62902产 地:中国大陆
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T62901VEGFR-2-IN-27;化合物 VEGFR-2-IN-27VEGFR-2-IN-27
VEGFR-2-IN-27 (compound 7a) is a potent inhibitor of VEGFR-2 (IC50: 14.8 nM) and can be used in anticancer studies.
价 格:¥电议型 号:T62901产 地:中国大陆
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T62900PDE10-IN-5;化合物 PDE10-IN-5PDE10-IN-5
PDE10-IN-5 is a phosphodiesterase 10 (PDE 10) inhibitor that can be used to study certain central nervous system disorders.
价 格:¥电议型 号:T62900产 地:中国大陆
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T6290Tanespimycin;坦螺旋霉素17-AAG|||CP 127374|||NSC 330507|||KOS 953;坦螺旋霉素|||17-AAG|||CP 127374|||NSC 330507|
Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).
价 格:¥电议型 号:T6290产 地:中国大陆
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T62629HPK1-IN-13;化合物 HPK1-IN-13HPK1-IN-13
HPK1-IN-13 is a potent inhibitor of HPK1. HPK1-IN-12 has potential for the study of HPK1-related diseases.
价 格:¥电议型 号:T62629产 地:中国大陆
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T61629CK2 inhibitor 3;化合物 CK2 inhibitor 3CK2 inhibitor 3
CK2 inhibitor 3 is a highly potent inhibitor of protein kinase CK2, exhibiting an IC50 value of 280 nM. It effectively inhibits the intracellular activity of CK2 and displays a notable impact on the viability of tumor cells. Moreover, CK2 inhibitor 3 demonstrates exceptional selectivity among a diverse panel of 320 kinases [1].
价 格:¥电议型 号:T61629产 地:中国大陆
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T60629PF-06649298;化合物 PF-06649298PF-06649298
PF-06649298 is an inhibitor of sodium-coupled citrate transporter which specifically interacts with NaCT with an IC 50 value of 16.2 μM to inhibits the transport of citrate in human hepatocytes. PF-06649298 can be used in regulating metabolism of glucose and metabolism of lipid [1] [2].
价 格:¥电议型 号:T60629产 地:中国大陆
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T56292-tert-Butyl-4-ethylphenol;2-叔丁基-4-乙基苯酚2-tert-Butyl-4-ethylphenol
2-tert-Butyl-4-ethylphenol can be used in life science-related research, and its molecular formula is C12H18O.
价 格:¥电议型 号:T5629产 地:中国大陆
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T5129SRI-011381 hydrochloride;化合物SRI-011381 hydrochlorideSRI-011381 hydrochloride [1629138-41-5(free base
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer´s disease.
价 格:¥电议型 号:T5129产 地:中国大陆