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  • T64218Keap1-Nrf2-IN-1 TFA；化合物 Keap1-Nrf2-IN-1 TFAKeap1-Nrf2-IN-1 TFA

    Keap1-Nrf2-IN-1 TFA (compound35) is a Keap1-Nrf2 protein-protein interaction inhibitor (IC50: 43 nM) that activates Nrf2-regulated cytoprotective responses. Keap1-Nrf2-IN-1 TFA antagonizes acetaminophen-induced liver injury in cellular and in vivo models.

    价 格：￥电议型 号：T64218产 地：中国大陆

  • T64217SM-433 hydrochloride；化合物 SM-433 hydrochlorideSM-433 hydrochloride

    SM-433 hydrochlorid is a Smac mimetic, an inhibitor of inhibitory apoptosis proteins (IAPs). SM-433 hydrochlorid is able to bind XIAP BIR3 protein with a potent IC50 <1 μM.

    价 格：￥电议型 号：T64217产 地：中国大陆

  • T64216TAK-960 hydrochloride；化合物 TAK-960 hydrochlorideTAK-960 hydrochloride

    TAK-960 hydrochloride is a potent, selective, orally active inhibitor of polo-like kinase 1 (PLK1) (IC50: 0.8 nM). TAK-960 hydrochloride inhibits the proliferation of a variety of tumour cell lines and significantly treats a variety of tumour xenografts.

    价 格：￥电议型 号：T64216产 地：中国大陆

  • T64215FGFR3-IN-2；化合物 FGFR3-IN-2FGFR3-IN-2

    FGFR3-IN-2 (compound 18b) is a potent and selective FGFR3 inhibitor that inhibits FGFR3 (IC50: 4.1 nM) and VEGFR2 (IC50: 570 nM).

    价 格：￥电议型 号：T64215产 地：中国大陆

  • T64214NXPZ-2；化合物 NXPZ-2NXPZ-2

    NXPZ-2 is an orally active Keap1-Nrf2protein-protein interaction (PPI) inhibitor (Ki: 95 nM, EC50: 120 and 170 nM). NXPZ-2 dose-dependently attenuates Aβ[1-42]-induced cognitive disturbances, enhances neuronal number and function, and enhances pathological alterations in the brain of Alzheimer´s disease (AD) mice.NXPZ-2 has potential for studies of Keap1-Nrf2 PPI inhibitors and AD-related disorders.

    价 格：￥电议型 号：T64214产 地：中国大陆

  • T64213Cap-dependent endonuclease-IN-3；化合物 Cap-dependent endonuclease-IN-3Cap-dependent endonuclease-IN-3

    Cap-dependent endonuclease-IN-3 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). Cap-dependent endonuclease-IN-3 has shown potential for the investigation of influenza A and B infections.

    价 格：￥电议型 号：T64213产 地：中国大陆

  • T64212Antiproliferative agent-5；化合物 Antiproliferative agent-5Antiproliferative agent-5

    Antiproliferative agent-5 (compound 4o) irreversibly and significantly inhibits the proliferation of gastric cancer cells. antiproliferative agent-5 blocks the cell cycle in G2/M phase, induces ROS accumulation and activates cellular autophagy. Antiproliferative agent-5 can be used in anti-cancer research.

    价 格：￥电议型 号：T64212产 地：中国大陆

  • T64211GLS1 Inhibitor-3；化合物 GLS1 Inhibitor-3GLS1 Inhibitor-3

    GLS1 Inhibitor-3 (compound C147) is a potent inhibitor of GLS1 (IC50: 27.98 nM) and exhibits anti-proliferative effects.

    价 格：￥电议型 号：T64211产 地：中国大陆

  • T64210ATX inhibitor 13；化合物 ATX inhibitor 13ATX inhibitor 13

    ATX inhibitor 13 (compound 10c) is an orally active ATX inhibitor (IC50: 3.4 nM). ATX inhibitor 13 is capable of blocking the cell cycle of RAW264.7 cells in the G2 phase, inhibiting cell proliferation and migration and inducing apoptosis. ATX inhibitor 13 exhibited an inhibitory effect on tumour colony formation.

    价 格：￥电议型 号：T64210产 地：中国大陆

  • T6421BRD73954；化合物BRD73954BRD73954

    BRD73954, an effective and specific HDAC inhibitor, which is with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.

    价 格：￥电议型 号：T6421产 地：中国大陆

  • T64209Anticancer agent 55；化合物 Anticancer agent 55Anticancer agent 55

    Anticancer Agent is a potent anti-cancer agent that exhibits anti-cancer effects by inhibiting cell viability and cell migration in a dose-dependent manner and inducing apoptosis.Anticancer Agent has potential for prostate and breast cancer research.

    价 格：￥电议型 号：T64209产 地：中国大陆

  • T64208EZH2-IN-9；化合物 EZH2-IN-9EZH2-IN-9

    EZH2-IN-9 is a potent inhibitor of EZH2, whose overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations) cause abnormal elevations in H3K27me3 and contribute to the growth and development of many tumours (e.g. breast cancer, prostate cancer, leukaemia, etc.). EZH2-IN-9 has shown potential for cancer research.

    价 格：￥电议型 号：T64208产 地：中国大陆

  • T64207FAK-IN-6；化合物 FAK-IN-6FAK-IN-6

    FAK-IN-6 is a potent inhibitor of FAK (IC50: 1.415 nM). FAK-IN-6 exhibits anti-proliferative effects on certain cancer cell lines and can be used to study pancreatic cancer.

    价 格：￥电议型 号：T64207产 地：中国大陆

  • T64206VGD071；化合物 VGD071VGD071

    VGD071, a compound that targets sortilin, presents a promising avenue for forthcoming research utilizing mouse models of breast cancer.

    价 格：￥电议型 号：T64206产 地：中国大陆

  • T64205HAMI 3379；化合物 HAMI 3379HAMI 3379

    HAMI 3379 is a potent and selective CysLT2 receptor antagonist. HAMI 3379 exhibits protective effects against acute and subacute ischaemic brain injury and reduces microglia-associated inflammation.

    价 格：￥电议型 号：T64205产 地：中国大陆

  • T64204NU5455；化合物 NU5455NU5455

    NU5455 is a selective, potent, orally active inhibitor of DNA-PKcs. NU5455 enhances the efficacy of locally released doxorubicin in liver tumour xenografts without causing any adverse effects. nU5455 enhances the efficacy and toxicity of topoisomerase inhibitors administered parenterally.

    价 格：￥电议型 号：T64204产 地：中国大陆

  • T64203T-Type calcium channel inhibitor 2；化合物 T-Type calcium channel inhibitor 2T-Type calcium channel inhi

    T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, acting on Cav3.1 (α1G) (IC50: 31.0 μM), Cav3.2 (α1H) (IC50: 83.1 μM), Cav3.3 (α1I) (α1H) ( T-Type calcium channel inhibitor 2 exhibited cytotoxicity against A549 and HCT-116 cells with IC50s of 5.0 and 6.4 μM, respectively.

    价 格：￥电议型 号：T64203产 地：中国大陆

  • T64202HCV-IN-40；化合物 HCV-IN-40HCV-IN-40

    HCV-IN-39 (Compound 18a) is a potent, orally active nucleoside inhibitor of hepatitis C virus (HCV) that acts on the GT1a replicon (EC50: 0.259 μM), GT1b replicon (EC50: 0.434 μM) and GT1b CES1 replicon (EC50. 0.069 μM).

    价 格：￥电议型 号：T64202产 地：中国大陆

  • T64201Antibacterial agent 70；化合物 Antibacterial agent 70Antibacterial agent 70

    Antibacterial agent 70 is a new dihydropyrimidinone-imidazole hybrid antimicrobial agent (MIC: 0.5 μg/ml).

    价 格：￥电议型 号：T64201产 地：中国大陆

  • T64200C5aR-IN-2；化合物 C5aR-IN-2C5aR-IN-2

    C5aR-IN-2 is a potent inhibitor of C5aR. C5aR-IN-2 has shown potential for the study of inflammatory diseases.

    价 格：￥电议型 号：T64200产 地：中国大陆

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