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T63750α-Amylase-IN-1;化合物α-Amylase-IN-1α-Amylase-IN-1
α-Amylase-IN-1 is an α-Amylase inhibitor (IC50: 0.5509 μM). α-Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging of DPPH free radicals, and can be used in the study of diabetes and oxidative stress-related diseases.
价 格:¥电议型 号:T63750产 地:中国大陆
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T6343Geldanamycin格尔德霉素格尔德霉素|||NSC 122750
Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.
价 格:¥电议型 号:T6343产 地:中国大陆
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T62750LRel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-p
rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine has an EC50 value of ≤ 0.05 μM and an E.max value of > 250 μM for TREM2.
价 格:¥电议型 号:T62750L产 地:中国大陆
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T62750TREM2 agonist-2;TREM2 激动剂2TREM2 agonist-2
TREM2 agonist-2 (I-192) is an orally active and potent myeloid triggered receptor 2 (TREM2) agonist for the study of neurodegenerative diseases.
价 格:¥电议型 号:T62750产 地:中国大陆
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T61750Anticancer agent 72;化合物 Anticancer agent 72Anticancer agent 72
Anticancer agent 72 (compound 8c) effectively inhibits the K+ channel, displaying significant potential as an anticancer treatment. Additionally, it induces apoptosis, a programmed cell death process [1].
价 格:¥电议型 号:T61750产 地:中国大陆
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T60750Neuronotoxicity-IN-1;化合物 Neuronotoxicity-IN-1Neuronotoxicity-IN-1
Neuronotoxicity-IN-1 is a pyridothiazine derivative. Neuronotoxicity-IN-1 is an inhibitor of kainic acid neurotoxicity with neuroprotective activity[1].
价 格:¥电议型 号:T60750产 地:中国大陆
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T5750Oxyberberine;氧化小檗碱Ketoberberine|||Berlambine|||8-Oxoberberine;氧化小檗碱|||Ketoberberine|||Berlambine|||8
Oxyberberine (8-Oxoberberine) is isolated from the methanol extract of A. mexicana. It has been used to study the SW480 human colon cancer cell line.
价 格:¥电议型 号:T5750产 地:中国大陆
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T4075012,14-Dichlorodehydroabietic acid;二氯脱氢松香酸12,14-Dichlorodehydroabietic acid
12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity. It effectively inhibits GABA-dependent chloride influx in the mammalian brain, functioning as a non-competitive antagonist of GABA A receptors. Moreover, 12,14-Dichlorodehydroabietic acid induces an elevation in cytosolic free calcium levels and promotes the release of neurotransmitters.
价 格:¥电议型 号:T40750产 地:中国大陆
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T4029BTB-1;化合物BTB1BTB 1|||NSC156750;BTB 1|||NSC156750
BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.
价 格:¥电议型 号:T4029产 地:中国大陆
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T39750CMP98;CMP98CMP98
CMP98, a proteolysis targeting chimera (PROTAC), exhibits a lack of VHL degradation efficacy. It can function as a negative control compound in comparison to CM11. CMP98 comprises two von Hippel-Lindau ligands operating within their active domains.
价 格:¥电议型 号:T39750产 地:中国大陆
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T38750ABBV-167;ABBV-167ABBV-167
ABBV-167 is a phosphate prodrug of the BCL-2 inhibitor venetoclax.
价 格:¥电议型 号:T38750产 地:中国大陆
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T37750Benanomicin B (formate);Benanomicin B (formate)Benanomicin B (formate)
Benanomicin B is a microbial metabolite that has been found inActinomycetesand has antifungal, fungicidal, and antiviral activities.1,2It is active against a variety of mammalian and plant pathogenic fungi, includingC. albicans,T. mentagrophytes,C. neoformans, andP. oryzae(MICs = 1.56-50 μg/ml).1Benanomicin B inhibits HIV-1 viral infection in MT-4 cells in a concentration-dependent manner.2
价 格:¥电议型 号:T37750产 地:中国大陆
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T37509Saccharocarcin B;Saccharocarcin BSaccharocarcin B
Saccharocarcin B was isolated from the fermentation broth of the actinomycete Saccharothrix aerocolongenes subsp.antibiotica SCC1886.
价 格:¥电议型 号:T37509产 地:中国大陆
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T37508Meconin;袂康宁Meconin
Meconin is a noscapine metabolite and a useful adjunct in detecting illicit opiate use.
价 格:¥电议型 号:T37508产 地:中国大陆
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T37507MCTR3;MCTR3MCTR3;MCTR3
Maresin conjugates in tissue regeneration 3 (MCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase, then to MCTR2 by γ-glutamyl transferase, and to MCTR3 by dipeptidase. MCTR3 accelerates tissue regeneration in planaria (1 and 100 nM) approximately as potently as MCTR2 and more potently than MCTR1. Pretreatment with MCTR3 pri
价 格:¥电议型 号:T37507产 地:中国大陆
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T37506MCTR2;MCTR2MCTR2;MCTR2
Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase then to MCTR2 by γ-glutamyl transferase. MCTR2 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR2 prior to E. coli administration reduces neutrophil infiltration, shor
价 格:¥电议型 号:T37506产 地:中国大陆
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T37505MCTR1;MCTR1MCTR1;MCTR1
Maresin conjugates in tissue regeneration 1 (MCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is then converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase. MCTR1 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR1 (50 ng/mouse, i.p.) prior to E. coli administration reduces neutrophil infiltration, shortens the inflam
价 格:¥电议型 号:T37505产 地:中国大陆
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T37504LCathepsin D and E FRET Substrate acetate;Cathepsin D and E FRET Substrate 醋酸Cathepsin D and E FRET S
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E but not for B, H, or L. Cathepsin D and E FRET Substrate acetate can be used in mechanistic studies on cathepsins D and E studies.
价 格:¥电议型 号:T37504L产 地:中国大陆
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T37504Cathepsin D and E FRET Substrate;Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH?Cathepsin
Mca-GKPILFFRL-Dpa-r-amide, FRET substrate for cathepsin D and E. Also cleaved by napsin A.
价 格:¥电议型 号:T37504产 地:中国大陆
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T37503Maresin 2;Maresin 23R,14S-diHDHA;3R,14S-diHDHA
Docosahexaenoic acid is an ω-3 fatty acid that is abundant in the brain and the retina and is known to be important in early development.[1] [2] Maresin 2 (MaR2) is a 13R,14S-dihydroxy DHA formed by recombinant human macrophage 12-lipoxygenase and soluble epoxide hydrolase co-incubated with DHA. [3] At 1 ng/mouse, MaR2 was shown to reduce neutrophil infiltration by 40% in a mouse model of peritonitis, and at 10 pM, MaR2 can enhance human macrophage phagocytosis of zymosan A by 90%. [3] Analytica
价 格:¥电议型 号:T37503产 地:中国大陆