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产品数:86101
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已选条件
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T6S1369Vitexinneurodegeneration,Vitexin,anti-cancer,anti-nociceptive,inhibit,Medicinal,anti-hypertensive,an
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can either inhibit or induce activities of CYP2C11 and CYP3A1. 5. Vitexin induces the novel p53-dependent metastatic and apoptotic pathway. 6. Vitexin protects brain against cerebral I/R injury, and this effect may be regulated by mitogen-activated protein kinase (MAPK) and apoptosis si
价 格:¥电议型 号:T6S1369产 地:中国大陆
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T8849PF-9601Nexcitotoxicity,neurodegenerative diseases,MAO,PF9601N,Monoamine Oxidase,MAO-B inhibitor,neur
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.
价 格:¥电议型 号:T8849产 地:中国大陆
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T19343sn-Glycerol 3-phosphateinhibit,Endogenous Metabolite,sn Glycerol 3 phosphate,snGlycerol 3phosphate,I
Glycerol 3-phosphate is produced by the reduction of dihydroxyacetone phosphate by NADH formed during glycolysis of the cytoplasmic glycerol 3-phosphate dehydrogenase pathway.
价 格:¥电议型 号:T19343产 地:中国大陆
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T6923Ozanimodneurosurgery,sphingosine 1-phosphate (S1P),LPL Receptor,inhibit,RPC1063,Lysophospholipid Rec
Ozanimod (RPC1063) is a specific oral S1P Receptor 1 modulator. Ozanimod has been used in trials studying the treatment of Crohn´s Disease, Ulcerative Colitis, Multiple Sclerosis, and Relapsing Multiple Sclerosis.
价 格:¥电议型 号:T6923产 地:中国大陆
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T99683-Piperidinyl(1-pyrrolidinyl)methanone hydrochloride3Piperidinyl(1pyrrolidinyl)methanone hydrochlori
3-Piperidinyl(1-pyrrolidinyl)methanone hydrochloride can be used in the synthesis of piperidin-4-yl-urea derivatives which are MCH-R1 antagonists.
价 格:¥电议型 号:T9968产 地:中国大陆
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T8202Kaempferol 3-O-gentiobiosideKaempferol 3Ogentiobioside,inhibit,Kaempferol 3 O gentiobioside,Inhibito
Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. It possesses activity against α-glucosidase and displays a carbohydrate enzyme inhibitory effect (IC50: 50 μM).
价 格:¥电议型 号:T8202产 地:中国大陆
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T11013L1Dextrorotation nimorazole phosphate ester TFADextrorotationnimorazolephosphateesterTFA
Dextrorotation nimorazole phosphate ester TFA is an anti-anaerobic and anti-parasitic agent.
价 格:¥电议型 号:T11013L1产 地:中国大陆
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TN1576Diallyl disulfidecholesterol biosynthesis,squalene monooxygenase,Inhibitor,inhibit,Diallyl disulfide
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.
价 格:¥电议型 号:TN1576产 地:中国大陆
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T9531MRT-14Inhibitor,Smo,Hedgehog,Smoothened,cancer,MRT 14,inhibit,MRT14,MRT-14
MRT-14 is a potent Smo antagonist and can be used in several types of cancers linked to abnormal Hh signaling studies.
价 格:¥电议型 号:T9531产 地:中国大陆
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T28036MI-2-2cell proliferation,inhibit,menin-MLL interaction,Epigenetic Reader Domain,Inhibitor,Hoxa9 expr
MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.
价 格:¥电议型 号:T28036产 地:中国大陆
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T7093RafoxanideHemonchus,Rafoxanide,energy metabolism,inhibit,antiparasitic,Parasite,Fasciola,Estrus ovis
Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.
价 格:¥电议型 号:T7093产 地:中国大陆
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T7297KG-501Epigenetic Reader Domain,inhibit,Inhibitor,KG 501,Naphthol AS-E,KG501,KG-501
KG-501 is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).
价 格:¥电议型 号:T7297产 地:中国大陆
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T8423ML417neuroprotection,dopaminergic,β-arrestin,ML417,ML-417,translocation,phosphorylation,neurons,ML 4
ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
价 格:¥电议型 号:T8423产 地:中国大陆
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T7117Sapropterin dihydrochloride(6R)-BH4,Sapropterin,Inhibitor,inhibit,Sapropterin dihydrochloride
Sapropterin dihydrochloride is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.
价 格:¥电议型 号:T7117产 地:中国大陆
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T6S1572Sauchinoneantioxidant,LPS,Diastereomeric,TNF-α,iNOS,anti-inflammatory,lignan,COX-2,inhibit,Nuclear f
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative stress in vivo and in vitro. 3. Sauchinone diminishes LPS-induced neutrophil activation and acute lung injury. 4. Sauchinone-induced HO-1 expression plays a key role in the vascular protective effects of Sauchinone in HUVEC. 5. Sauchinone protects skin keratinocytes through inhi
价 格:¥电议型 号:T6S1572产 地:中国大陆
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T8478SC-43antiproliferative,Inhibitor,SC-43,SHP-1,PTPN6,Phosphatase,Apoptosis,caspase-3,SC 43,anti-fibrot
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
价 格:¥电议型 号:T8478产 地:中国大陆
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T9584UNC6934Inhibitor,UNC6934,Histone Methyltransferase,inhibit,UNC 6934,UNC-6934
UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.
价 格:¥电议型 号:T9584产 地:中国大陆
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T6778BDA-366Inhibitor,BDA-366,Antitumor,Bcl-2 Family,inhibit,Bcl2-BH4 domain,Anticancer,BDA 366,Antiapopt
BDA-366 is a potent Bcl2 antagonist, binding Bcl2-BH4 domain with high affinity and selectivity (Ki = 3.3 nM). BDA-366 induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells[1].
价 格:¥电议型 号:T6778产 地:中国大陆
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TQ0083NI-57Inhibitor,inhibit,NI 57,NI-57,NI57,Epigenetic Reader Domain
NI-57 is an inhibitor of proteins of bromodomain and plant homeodomain finger-containing (BRPF) family, with IC50s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively.
价 格:¥电议型 号:TQ0083产 地:中国大陆
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T6566Levobupivacaine hydrochlorideCNS toxicity,gastric cancer,Na channels,Erastin,Inhibitor,analgesic,ana
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic.
价 格:¥电议型 号:T6566产 地:中国大陆