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T16116MLN-4760MLN-4760
MLN-4760 is an effective and selective inhibitor of human ACE2 (IC50, 0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM).
价 格:¥电议型 号:T16116产 地:美洲
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T16117Pevonedistat hydrochloridePevonedistat hydrochloride,MLN4924 hydrochloride,
Pevonedistat hydrochloride is an effective and selective inhibitor of NEDD8-activating enzyme (IC50: 4.7 nM).
价 格:¥电议型 号:T16117产 地:美洲
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T16118MLS0315771MLS0315771
MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM).
价 格:¥电议型 号:T16118产 地:美洲
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T16120MLT-748MLT-748
MLT-748 is an effective, selective, and allosteric MALT1 inhibitor. It binds MALT1 in the allosteric Trp580 pocket (IC50: 5 nM).
价 格:¥电议型 号:T16120产 地:美洲
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T1639AmlexanoxAmlexanox,Amoxanox,CHX3673
Amlexanox is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist
价 格:¥电议型 号:T1639产 地:美洲
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T1667TandutinibTandutinib,CT53518,MLN518
Tandutinib (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR.
价 格:¥电议型 号:T1667产 地:美洲
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T1757ML323ML323
ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay (IC50: 76 nM) and in orthogonal gel-based assays using K63-linked diubiquitin (di-Ub) (IC50: 174 nM 820 nM)and monoubiquitinated PCNA (Ub-PCNA) (IC50: 820 nM) as substrates, respec
价 格:¥电议型 号:T1757产 地:美洲
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T1838INK 128INK 128,MLN0128,Sapanisertib
INK 128 is an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity.
价 格:¥电议型 号:T1838产 地:美洲
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T1893ML 161ML 161
ML 161 is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thrombin-induced platelet activation.
价 格:¥电议型 号:T1893产 地:美洲
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T1943ML347ML347,LDN 193719,
ML347(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the selectivity for ALK2 is >300-fold than ALK3.
价 格:¥电议型 号:T1943产 地:美洲
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T1977DorsomorphinDorsomorphin,Compound C,BML-275
Dorsomorphin is an effective and specific inhibitor of AMPK (AMP-activated protein kinase), which is induced by AICAR and metformin.
价 格:¥电议型 号:T1977产 地:美洲
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T1983CAY10603CAY10603,BML-281,HDAC6 Inhibitor
CAY10603 is a potent and selective inhibitor of HDAC6.
价 格:¥电议型 号:T1983产 地:美洲
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T2016Ixazomib CitrateIxazomib Citrate,MLN9708,
MLN2238 suppresses the chymotrypsin-like proteolytic (β5) site of the 20S proteasome(Ki50=0.93 nM, IC50=3.4 nM/). The biologically active form of MLN9708 is MLN2238 in aqueous solutions or plasma.
价 格:¥电议型 号:T2016产 地:美洲
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T2033BML-277BML-277,BML277,BML 277
BML-277 is a selective checkpoint kinase 2 (Chk2) inhibitor.
价 格:¥电议型 号:T2033产 地:美洲
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T2122IxazomibIxazomib,MLN2238,
MLN2238, a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also inhibits the caspase-like (β1) and trypsin-like
价 格:¥电议型 号:T2122产 地:美洲
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T2298ML204ML204
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
价 格:¥电议型 号:T2298产 地:美洲
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T2463ML141ML141,CID-2950007,
ML141 is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).
价 格:¥电议型 号:T2463产 地:美洲
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T4540ML 18ML 18
ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.
价 格:¥电议型 号:T4540产 地:美洲
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T4619ML-098ML-098,ML098,ML 098
ML-098 is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).
价 格:¥电议型 号:T4619产 地:美洲