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T16679PT2977PT2977,MK-6482,
PT2977 is a potential treatment for clear cell renal cell carcinoma (ccRCC). PT2977 is an orally active and selective HIF-2α inhibitor (IC50: 9 nM). PT2977, as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile.
价 格:¥电议型 号:T16679产 地:美洲
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T16683Pumosetrag HydrochloridePumosetrag Hydrochloride,MKC-733,DDP-733
Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.
价 格:¥电议型 号:T16683产 地:美洲
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T1677LMontelukast sodiumMontelukast sodium,MK0476,
Montelukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury.
价 格:¥电议型 号:T1677L产 地:美洲
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T1743AprepitantAprepitant,L-754030,MK-869
Aprepitant is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer.
价 格:¥电议型 号:T1743产 地:美洲
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T1790Fosaprepitant dimeglumineFosaprepitant dimeglumine,L785298,MK-0517
Fosaprepitant Dimeglumine is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively
价 格:¥电议型 号:T1790产 地:美洲
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T1799CancidasCancidas,L 743873,MK 0991
Cancidas is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. This agent is active against Aspergillus and Candida species.
价 格:¥电议型 号:T1799产 地:美洲
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T1913MK3697MK3697
MK-3697, an isonicotinamide small molecule, acts as a potent and selective Orexin 2 receptor antagonist (Ki: 0.95 nM).
价 格:¥电议型 号:T1913产 地:美洲
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T1928AnacetrapibAnacetrapib,MK-0859,
Anacetrapib (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cho
价 格:¥电议型 号:T1928产 地:美洲
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T19429MK-6240MK-6240
MK-6240 is a tau positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs). MK-6240 exhibits high specificity and selectivity for binding to NFTs.
价 格:¥电议型 号:T19429产 地:美洲
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T1952MK-2206 dihydrochlorideMK-2206 dihydrochloride,MK-2206 2HCl,
MK-2206 is a highly specific inhibitor of Akt1/2/3 (IC50: 8/12/65 nM in cell-free assays) and no effect on the activities of 250 other protein kinases.
价 格:¥电议型 号:T1952产 地:美洲
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T2077AdavosertibAdavosertib,MK-1775,AZD1775
MK-1775 is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.
价 格:¥电议型 号:T2077产 地:美洲
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T2134Dorzolamide hydrochlorideDorzolamide hydrochloride,MK507 hydrochloride,L671152 hydrochloride
Dorzolamide Hydrochloride is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate ions. Distrib
价 格:¥电议型 号:T2134产 地:美洲
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T2239Raltegravir potassiumRaltegravir potassium,MK 0518 potassium salt,Raltegravir potassium salt
Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
价 格:¥电议型 号:T2239产 地:美洲
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T2239LRaltegravirRaltegravir,MK-0518,
Raltegravir is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.
价 格:¥电议型 号:T2239L产 地:美洲
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T2316OmarigliptinOmarigliptin,MK-3102,
Omarigliptin has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency.
价 格:¥电议型 号:T2316产 地:美洲
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T2509TozasertibTozasertib,VX 680,MK-0457
MK-0457 is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C). It shows selectivity against more than 190 different kinases.
价 格:¥电议型 号:T2509产 地:美洲
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T2517MK-8776MK-8776,SCH900776,MK 8776
CHK1 Inhibitor MK-8776 is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.
价 格:¥电议型 号:T2517产 地:美洲
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T2537Tirofiban hydrochloride monohydrateTirofiban hydrochloride monohydrate,Tirofiban Hydrochloride,MK-38
Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist.
价 格:¥电议型 号:T2537产 地:美洲