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T25739LLinogliride fumarate;化合物 T25739LMcN 3935|||McN-3935|||McN3935;McN 3935|||McN-3935|||McN3935
Linogliride fumarate is the fumarate salt of Linogliride. Linogliride is a guanidine-based inhibitor of insulin secretion and a structural analog of pirogliride with hypoglycemic activity. It blocks ATP-sensitive potassium channels in the pancreatic beta cell membrane, thereby stimulating insulin secretion and improving glucose tolerance.
价 格:¥电议型 号:T25739L产 地:中国大陆
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T25739Linogliride;化合物 T25739McN-3935|||McN3935|||McN 3935|||Linogliridum|||Linoglirida;McN-3935|||McN3935|
Linogliride is a guanidine-based inhibitor of insulin secretion and a structural analog of pirogliride with hypoglycemic activity. It blocks ATP-sensitive potassium channels in the pancreatic beta cell membrane, thereby stimulating insulin secretion and improving glucose tolerance.
价 格:¥电议型 号:T25739产 地:中国大陆
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T25593Labetuzumab govitecan;化合物 T25593IMMU-130|||Labetuzumab-SN38|||hMN14-SN38|||IMMU130|||IMMU 130;IMMU-1
Labetuzumab govitecan is an anti-CEACAM5/SN-38 antibody-drug conjugate for therapy of refractory or relapsing metastatic colorectal cancer.
价 格:¥电议型 号:T25593产 地:中国大陆
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T23897CLK1/2-IN-3;CLK1/2抑制剂3CLK1/2 inhibitor 3|||CLK1/2-inhibitor-3|||CLK1/2 IN 3|||CLK1/2IN3;CLK1/2 inhib
CLK1/2-IN-3 (Cpd-3) is a potent and selective CLK1 and CLK2 inhibitor with antiproliferative activity and inhibits the activities of CLK1, CLK2, SRPK1, SRPK2, and SRPK3.CLK1/2-IN-3 induces nuclear speckle enlargement, which induces S6K pre-mRNA-selective splicing and subsequent inhibition of cell growth of multiple cancer cell types. cancer cell types cell growth.
价 格:¥电议型 号:T23897产 地:中国大陆
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T2158Nutlin-3;化合物Nutlin-3Nutlin3;Nutlin3
Nutlin-3 is an MDM2 antagonist.Nutlin-3 inhibits the MDM2-p53 interaction (IC50: 0.09 μM) and activates p53. Antiproliferative agent; chemotherapeutic agent; induces apoptosis in Y cells.
价 格:¥电议型 号:T2158产 地:中国大陆
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T1954SRPIN340;化合物SRPIN340SRPK inhibitor;SRPK inhibitor
SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).
价 格:¥电议型 号:T1954产 地:中国大陆
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T18953CY7-N3;化合物 T18953Sulfo-Cyanine7-N3;Sulfo-Cyanine7-N3
CY7-N3 (Sulfo-Cyanine7-N3) is a NIR dye azide for Click Chemistry with water-soluble.
价 格:¥电议型 号:T18953产 地:中国大陆
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T18942LCy5-N3 triethylamine salt;Cy5-N3三乙胺盐Cy5-N3 triethylamine salt(1621101-43-6 free base);Cy5-N3 triethy
Cy5-N3 triethylamine salt is a turnip-based fluorescent dye.CY5-N3 can be used to study cellular imaging.
价 格:¥电议型 号:T18942L产 地:中国大陆
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T18942Cy5-N3;花菁染料5-叠氮Sulfo-Cyanine5-azide;Sulfo-Cyanine5-azide
CY5-N3 (Sulfo-Cyanine5-azide) is an anthocyanin fluorescent dye containing azide groups. CY5-N3 is used for cell imaging, tissue imaging, and in vivo imaging.
价 格:¥电议型 号:T18942产 地:中国大陆
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T18941Cy3-N3;化合物 T18941Cy3-N3|||Cy3 N3|||Cy3N3|||Cy-3-N3;Cy3-N3|||Cy3 N3|||Cy3N3|||Cy-3-N3
Cy3-N3 is a fluorescent dye used to label for nucleic acid and protein.
价 格:¥电议型 号:T18941产 地:中国大陆
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T1873Tenovin-3;化合物Tenovin-3Tenovin3;Tenovin3
Tenovin-3 acts as a p53 activator.
价 格:¥电议型 号:T1873产 地:中国大陆
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T18662(S,R,S)-AHPC-C2-PEG4-N3;化合物 T18662VH032-C2-PEG4-N3;VH032-C2-PEG4-N3
(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate combining the (S,R,S)-AHPC-based VHL ligand with a 4-unit polyethylene glycol (PEG) linker, employed in PROteolysis TAgeting Chimera (PROTAC) technology. This compound facilitates the creation of vRucaparib-TP4, a potent PARP1 degrader demonstrating a half-maximal degrading concentration (DC50) of 82 nM[1].
价 格:¥电议型 号:T18662产 地:中国大陆
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T18644PTAD-PEG4-N3;化合物 T18644PTAD-PEG4-N3
PTAD-PEG4-N3 is a cleavable four-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker, utilized in ADC synthesis[1].
价 格:¥电议型 号:T18644产 地:中国大陆
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T18615Phenol-amido-C1-PEG3-N3;化合物 T18615PROTAC Linker 21;PROTAC Linker 21
Phenol-amido-C1-PEG3-N3, also known as PROTAC Linker 21, is a PEG-based linker utilized for synthesizing PROTACs.
价 格:¥电议型 号:T18615产 地:中国大陆
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T18486NH2-C5-PEG4-N3-L-Lysine-PEG3-N3;化合物 T18486NH2-C5-PEG4-N3-L-Lysine-PEG3-N3
NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a seven-unit cleavable polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker employed in the synthesis of ADCs[1].
价 格:¥电议型 号:T18486产 地:中国大陆
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T18476N3-Ph-NHS ester琥珀酰亚胺基 4-叠氮基苯甲酸酯琥珀酰亚胺基 4-叠氮基苯甲酸酯
N3-Ph-NHS ester is a noncleavable ADC linker. N3-Ph-NHS ester can be used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18476产 地:中国大陆
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T18475N3-PEG6-Propanehydrazide;化合物 T18475N3-PEG6-Propanehydrazide
N3-PEG6-Propanehydrazide is a polyethylene glycol (PEG) derived linker, specifically designed for use in the synthesis of proteolysis targeting chimeras (PROTACs) [1].
价 格:¥电议型 号:T18475产 地:中国大陆
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T18474N3-PEG5-aldehyde;化合物 T18474N3-PEG5-aldehyde
N3-PEG5-aldehyde is a 5-unit cleavable polyethylene glycol (PEG) linker specifically designed for antibody-drug conjugates (ADCs) synthesis[1].
价 格:¥电议型 号:T18474产 地:中国大陆
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T18473N3-PEG3-vc-PAB-MMAE;化合物 T18473N3PEG3vcPABMMAE|||N3-PEG3-vc-PAB-MMAE|||N-3-PEG3-vc-PAB-MMAE|||N3 PEG3
N3-PEG3-vc-PAB-MMAE, a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC), features the integration of monomethyl auristatin E (MMAE), a tubulin inhibitor, via a 3-unit polyethylene glycol (PEG) linker. This compound demonstrates significant antitumor activity.
价 格:¥电议型 号:T18473产 地:中国大陆
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T18472N3-PEG3-Propanehydrazide;化合物 T18472N3-PEG3-Propanehydrazide
N3-PEG3-Propanehydrazide serves as a PEG-based PROTAC linker, employed for PROTAC synthesis [1].
价 格:¥电议型 号:T18472产 地:中国大陆