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T18624NH2-Ph-C4-acid-NH2-Me;化合物 T18624PROTAC Linker 31;PROTAC Linker 31
NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based compound utilized for the synthesis of PROTACs. [1]
价 格:¥电议型 号:T18624产 地:中国大陆
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T18623Boc-NH-PEG2-C2-amido-C4-acid;化合物 T18623PROTAC Linker 30;PROTAC Linker 30
Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
价 格:¥电议型 号:T18623产 地:中国大陆
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T18622BnOH-NH-bis-(C2-S)-propane-O-isoprene ester;化合物 T18622PROTAC Linker 29;PROTAC Linker 29
BnOH-NH-bis-(C2-S)-propane-O-isoprene ester (PROTAC Linker 29) is an alkyl ether-based linker primarily utilized in the synthesis of PROTACs.
价 格:¥电议型 号:T18622产 地:中国大陆
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T18621Tos-PEG1-O-CH2COOH;化合物 T18621PROTAC Linker 28|||PROTAC Linker 28|||Tos PEG1 O CH2COOH|||TosPEG1OCH2C
Tos-PEG1-O-CH2COOH (PROTAC Linker 28), a PEG-based PROTAC linker, finds applicability in PROTACs synthesis [1].
价 格:¥电议型 号:T18621产 地:中国大陆
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T18620Tos-PEG2-NH2;化合物 T18620PROTAC Linker 27;PROTAC Linker 27
Tos-PEG2-NH2 (PROTAC Linker 27) is a Polyethylene Glycol (PEG)-based linker used for the synthesis of Proteolysis-Targeting Chimeras (PROTACs)[1].
价 格:¥电议型 号:T18620产 地:中国大陆
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T18619Bis-PEG1-C-PEG1-CH2COOH;化合物 T18619PROTAC Linker 26;PROTAC Linker 26
Bis-PEG1-C-PEG1-CH2COOH (PROTAC Linker 26) is a PEG-based linker suitable for the synthesis of PROTACs, compound complexes that selectively degrade target proteins[1].
价 格:¥电议型 号:T18619产 地:中国大陆
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T18618Bis-NH2-C1-PEG3化合物 T18618PROTAC Linker 24
Bis-NH2-C1-PEG3 (PROTAC Linker 24) is a polyethylene glycol (PEG)-based linker compound utilized in the synthesis of PROTACs. This compound serves as a critical component in constructing PROTAC molecules, facilitating the targeted degradation of specific proteins[1].
价 格:¥电议型 号:T18618产 地:中国大陆
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T18617NH2-C5-NH-Boc;N-(5-氨基戊基)氨基甲酸叔丁酯PROTAC Linker 23;N-(5-氨基戊基)氨基甲酸叔丁酯|||PROTAC Linker 23
NH2-C5-NH-Boc (PROTAC Linker 23) (PROTAC Linker 23) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T18617产 地:中国大陆
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T18616NH2-C2-NH-BocN-叔丁氧羰基-1,2-乙二胺PROTAC Linker 22|||N-叔丁氧羰基-1,2-乙二胺
NH2-C2-NH-Boc (PROTAC Linker 22) (PROTAC Linker 22) is a alkyl chain-based PROTAC linker. NH2-C2-NH-Boc can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T18616产 地:中国大陆
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T18615Phenol-amido-C1-PEG3-N3;化合物 T18615PROTAC Linker 21;PROTAC Linker 21
Phenol-amido-C1-PEG3-N3, also known as PROTAC Linker 21, is a PEG-based linker utilized for synthesizing PROTACs.
价 格:¥电议型 号:T18615产 地:中国大陆
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T18614Bis-Tos-PEG4化合物Bis-Tos-PEG4Tetraethylene glycol di(p-toluenesulfonate)|||PROTAC Linker 16|||1,11-Bis
Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker. Bis-Tos-PEG4 can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T18614产 地:中国大陆
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T18613MV-1-NH-Me;化合物 T18613PROTAC IAP binding moiety 2;PROTAC IAP binding moiety 2
MV-1-NH-Me, an MV-1-derived IAP ligand, connects to an ABL inhibitor through a linker, resulting in the formation of SNIPER[1].
价 格:¥电议型 号:T18613产 地:中国大陆
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T18612Bestatin-amido-Me;化合物 T18612PROTAC IAP binding moiety 1;PROTAC IAP binding moiety 1
Bestatin-amido-Me, a derivative of Bestatin, acts as an IAP ligand and interacts with ABL inhibitor through a linker to produce SNIPER[1].
价 格:¥电议型 号:T18612产 地:中国大陆
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T18611AP1867-2-(carboxymethoxy);化合物 T18611PROTAC FKBP12-binding moiety 2;PROTAC FKBP12-binding moiety 2
AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1].
价 格:¥电议型 号:T18611产 地:中国大陆
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T18610PROTAC FKBP Degrader-3;化合物 T18610PROTAC FKBP Degrader-3
PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an VHL binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader[1].
价 格:¥电议型 号:T18610产 地:中国大陆
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T18609PROTAC ERRα Degrader-2;化合物 T18609PROTAC ERRα Degrader-2
PROTAC ERRα Degrader-2 is a compound consisting of an MDM2 ligand binding group, a linker, and an estrogen-related receptor alpha (ERRα) binding group. This compound is designed to specifically degrade estrogen-related receptor alpha (ERRα), acting as an ERRα degrader[1].
价 格:¥电议型 号:T18609产 地:中国大陆
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T18607PROTAC ER Degrader-3;化合物 T18607PROTAC ER Degrader-3
PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, specifically compound LP2. PAC serves as the linker for ADCs and PROTACs that are conjugated to an antibody. Notably, when PAC is conjugated to an antibody, it exhibits enhanced degradation of estrogen receptor-alpha (ERα) compared to PROTAC alone [1].
价 格:¥电议型 号:T18607产 地:中国大陆
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T18606PROTAC ER Degrader-2;化合物 T18606PROTAC ER Degrader-2
PROTAC ER Degrader-2 serves as a synthesis intermediate for the production of PAC, a compound that incorporates the ADCs linker and PROTACs, which are subsequently conjugated to an antibody. PAC, exhibits a greater capability to degrade estrogen receptor-alpha (ERα) compared to PROTAC (without the presence of an antibody)[1].
价 格:¥电议型 号:T18606产 地:中国大陆
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T18605PROTAC ERα Degrader-2;化合物 T18605PROTAC ERα Degrader-2
PROTAC ERα Degrader-2 is composed of a cIAP1 ligand binding group, a linker, and an estrogen receptor α (ERα) binding group, serving as an ERα degrader. It achieves maximal ERα degradation in human mammary tumor MCF7 cells at a concentration of 30 μM. Degradation inducers that utilize cIAP1 are referred to as specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].
价 格:¥电议型 号:T18605产 地:中国大陆
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T18603PROTAC BRD4 degrader for PAC-1;化合物 T18603PROTAC BRD4 degrader for PAC-1
PROTAC BRD4 degrader for PAC-1 (compound 5) is a chimeric BET degrader GNE-987 conjugated with a disulfide-containing linker[1]. This PROTAC-linker conjugate specifically targets and degrades BRD4, enabling selective proteolysis of PAC-1.
价 格:¥电议型 号:T18603产 地:中国大陆