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T78164JBSNF-000028 hydrochloride;化合物 JBSNF-000028 hydrochlorideJBSNF-000028 hydrochloride
JBSNF-000028 hydrochloride is a potent inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 values of 0.033 μM for human NNMT (hNNMT), 0.19 μM for monkey NNMT (mkNNMT), and 0.21 μM for mouse NNMT (mNNMT). This orally active compound is utilized in the study of metabolic disorders [1].
价 格:¥电议型 号:T78164产 地:中国大陆
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T78163JBSNF-000028 TFA;化合物 JBSNF-000028 TFAJBSNF-000028 TFA
JBSNF-000028 TFA, a nicotinamide N-methyltransferase (NNMT) inhibitor, exhibits oral activity with inhibitory concentration 50 (IC50) values of 0.033 μM, 0.19 μM, and 0.21 μM for human NNMT (hNNMT), monkey NNMT (mkNNMT), and mouse NNMT (mNNMT) respectively. It is applicable in metabolic disorder research [1].
价 格:¥电议型 号:T78163产 地:中国大陆
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T78104Fosnetupitant chloride monohydrochloride;化合物 Fosnetupitant chloride monohydrochloridePronetupitant c
Fosnetupitant chloride monohydrochloride (Pro-netupitant chloride monohydrochloride) is a selective NK1 antagonist exhibiting high affinity for the human NK1 receptor with a pK i value of 9.5, and a lower affinity for the NK3 receptor with a pK i of 6.1. It serves as a methylene phosphate prodrug of Netupitant [1].
价 格:¥电议型 号:T78104产 地:中国大陆
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T77882SN38-COOH;化合物 SN38-COOHSN38-COOH
SN38-COOH, the active metabolite of the topoisomerase I inhibitor irinotecan, is utilized in the synthesis of antibody-drug conjugates (ADCs). It functions by inhibiting DNA and RNA synthesis [1] [2].
价 格:¥电议型 号:T77882产 地:中国大陆
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T77837CL2E-SN38 TFA;化合物 CL2E-SN38 TFACL2E-SN38 TFA
CL2E-SN-38 TFA, a structurally stable and highly releasable antibody drug conjugate (ADC), comprises SN-38, the active metabolite of Irinotecan derived from camptothecins, known for its Topoisomerase I inhibitory activity [1].
价 格:¥电议型 号:T77837产 地:中国大陆
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T77830NHS-PEG2-SS-PEG2-NHS;化合物 NHS-PEG2-SS-PEG2-NHSNHS-PEG2-SS-PEG2-NHS
NHS-PEG2-SS-PEG2-NHS is a cleavable, four-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T77830产 地:中国大陆
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T7773DPPC;二棕榈酸磷脂酰胆碱1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL|||129Y83;1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO
DPPC (129Y83) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes.
价 格:¥电议型 号:T7773产 地:中国大陆
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T77657MSNBA;化合物MSNBAMSNBA
MSNBA is a selective and potent inhibitor of fructose transport through GLUT5 and also acts as a probe of the GLUT5 transporter. MSNBA inhibited GLUT5 fructose uptake in MCF7 cells with KI of 3.2±0.4 μM.
价 格:¥电议型 号:T77657产 地:中国大陆
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T77613SNX7;化合物SNX7WAY-323879;WAY-323879
SNX7 (WAY-323879) is an inhibitor of the cell cycle protein-dependent kinase inhibitor (CDKI) pathway. SNX7 can be utilized as a tool for investigating the aging process and other diseases associated with CDKI.
价 格:¥电议型 号:T77613产 地:中国大陆
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T77404Tesnatilimab;特拉佐利单抗IPH-23XX|||JNJ-64304500|||JNJ 4500;IPH-23XX|||JNJ-64304500|||JNJ 4500
Tesnatilimab is a potent humanized IgG4 monoclonal antibody that binds to the immune-activating receptor NKG2D. Tesnatilimab has potential immunomodulatory and anti-inflammatory activity and can be used to study active ulcerative colitis.
价 格:¥电议型 号:T77404产 地:中国大陆
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T772301-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine;化合物 1-O-Hexadecyl-2-O-docosahexaeno
1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine, an endogenous metabolite found in urine, has applications in obesity research [1] [2].
价 格:¥电议型 号:T77230产 地:中国大陆
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T7680GSNKGAIIGLM(131602-53-4(free base));BETA-淀粉样蛋白片断25-35Amyloid beta-peptide(25-35);Amyloid beta-peptid
GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) is the fragment Aβ(25-35) of the Alzheimer´s amyloid β-peptide.
价 格:¥电议型 号:T7680产 地:中国大陆
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T76586(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat);化合物 (Asn10,Leu11,D-Trp12)
(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent antagonist of the PTH-1R [1] [2].
价 格:¥电议型 号:T76586产 地:中国大陆
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T76512Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2;化合物 Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2Ac-Ser-Gln-Asn-Tyr-Pro-Val-
Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 is a peptide substrate specific to HIV-1 protease, serving as the variable component in peptidolytic assays designed to measure the enzyme´s inhibition [1] [2].
价 格:¥电议型 号:T76512产 地:中国大陆
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T76470GVLSNVIGYLKKLGTGALNAVLKQ;化合物 GVLSNVIGYLKKLGTGALNAVLKQGVLSNVIGYLKKLGTGALNAVLKQ
GVLSNVIGYLKKLGTGALNAVLKQ (PGQ) is a 24-amino acid antimicrobial peptide capable of forming an α-helix structure. It exhibits activity against both Gram-negative and Gram-positive bacteria, as well as the yeast Candida albicans [1].
价 格:¥电议型 号:T76470产 地:中国大陆
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T76329[Asn18] Endothelin-1, human;化合物 [Asn18] Endothelin-1, human[Asn18] Endothelin-1, human
[Asn18] Endothelin-1, human, a peptide, represents a predominant isoform of Endothelin, significantly contributing to the regulation of vascular function [1].
价 格:¥电议型 号:T76329产 地:中国大陆
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T75695H-Asn(glcnac-beta-D)-OH;化合物 H-Asn(glcnac-beta-D)-OHH-Asn(glcnac-beta-D)-OH
H-Asn(glcnac-beta-D)-OH is an endogenous metabolite found in urine, utilized in the research of NGLY1-CDDG [1] [2].
价 格:¥电议型 号:T75695产 地:中国大陆
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T756881-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol;化合物 1-Stearoyl-2-arachidonoyl-sn-glycero-3-ph
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol is an intrinsic metabolite and a component of the cell membrane [1].
价 格:¥电议型 号:T75688产 地:中国大陆
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T75112LSN3160440;化合物 LSN3160440LSN3160440
LSN3160440 is an allosteric modulator of GLP-1R, functioning as a protein-protein interaction (PPI) stabilizer or molecular glue. It aids in the binding of inactive GLP-1 (9-36) NH2 to GLP-1R, enhancing receptor activation and potential therapeutic effects [1] [2].
价 格:¥电议型 号:T75112产 地:中国大陆
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T74462SNIPER(TACC3)-11;化合物 SNIPER(TACC3)-11SNIPER(TACC3)-11
SNIPER(TACC3)-11 is a potent degrader of the FGFR3-TACC3 protein, effectively diminishing its levels and inhibiting the proliferation of cancer cells positive for FGFR3-TACC3 [1].
价 格:¥电议型 号:T74462产 地:中国大陆