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T62986CCG-271423；化合物 CCG-271423CCG-271423
CCG-271423 is a potent and selective inhibitor of GRK5, acting on both GRK5 (IC50: 0.0021 μM) and GRK2 (IC50: 44 μM). CCG-271423 reduces Ca2+ transients and inhibits cardiomyocyte contractility.
价 格：￥电议型 号：T62986产 地：中国大陆
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T62985Cofrogliptin；化合物 CofrogliptinCofrogliptin
Cofrogliptin (HSK7653) (compound 2) is a tetrahydropyran derivative that is an orally active DPP-4 inhibitor with long-lasting hypoglycaemic effects.Cofrogliptin (compound 2) has potential for studies in type 2 diabetes mellitus (T2DM).
价 格：￥电议型 号：T62985产 地：中国大陆
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T62984MAT2A-IN-2；化合物 MAT2A-IN-2MAT2A-IN-2
MAT2A-IN-2 is a potent inhibitor of MAT2A. MAT2A-IN-2 has potential for cancer disease research.
价 格：￥电议型 号：T62984产 地：中国大陆
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T62983Raltegravir sodium；化合物 Raltegravir sodiumRaltegravir sodium
Raltegravir (MK 0518) sodium is a potent, orally active HIV integrase (IN) inhibitor.
价 格：￥电议型 号：T62983产 地：中国大陆
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T62982Aripiprazole monohydrate；化合物 Aripiprazole monohydrateAripiprazole monohydrate
Aripiprazole (OPC-14597) monohydrate is an atypical antipsychotic that is a potent, high-affinity partial agonist of the dopamine D2 receptor.Aripiprazole monohydrate is an inverse agonist of the 5-HT2B and 5-HT2A receptors, and is active on 5-HT1A, 5-HT2C, D3 and D4. Aripiprazole monohydrate can be used to study schizophrenia and COVID19.
价 格：￥电议型 号：T62982产 地：中国大陆
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T62981KRAS inhibitor-17；化合物 KRAS inhibitor-17KRAS inhibitor-17
KRAS inhibitor-17 (compound 3-9) is a potent inhibitor of KRAS G12C (IC50: 3.37 μM). KRAS inhibitor-17 exhibits p-ERK inhibition with IC50 = 9.25 μM in MIA PaCA-2 cells and >33.3 μM in A549 cells. KRAS inhibitor-17 has the potential to be studied in pancreatic, colorectal and lung cancers.
价 格：￥电议型 号：T62981产 地：中国大陆
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T62980GGTI-286 hydrochloride；化合物 GGTI-286 hydrochlorideGGTI-286 hydrochloride
GGTI-286 hydrochloride is a potent inhibitor of GGTase I (IC50: 2 μM) and is also effective in inhibiting K-Ras4B (IC50: 1 μM). farnesylation (IC50=2 and >30 μM).
价 格：￥电议型 号：T62980产 地：中国大陆
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T62979OTS447；化合物 OTS447OTS447
OTS447 is a potent inhibitor of FLT3 (IC50: 21 nM).
价 格：￥电议型 号：T62979产 地：中国大陆
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T62978HIV-IN-3；化合物 HIV-IN-3HIV-IN-3
HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.
价 格：￥电议型 号：T62978产 地：中国大陆
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T62977MA242 free base；化合物 MA242 free baseMA242 free base
MA242 free base is a specific dual inhibitor of MDM2 and NFAT1 that induces apoptosis in pancreatic cancer cell lines. MA242 free base binds directly to MDM2 and NFAT1 with high affinity, induces MDM2 and NFAT1 protein degradation and inhibits NFAT1-mediated MDM2 transcription.
价 格：￥电议型 号：T62977产 地：中国大陆
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T62976Carbonic anhydrase inhibitor 5；化合物 Carbonic anhydrase inhibitor 5Carbonic anhydrase inhibitor 5
Carbonic anhydrase inhibitor 5 is a potent and selective inhibitor of human carbonic anhydrase (hCA), acting on hCA II (IC50: 42.9 nM), hCA IX (IC50: 47.6 nM) and hCA XII (IC50: 6.7 nM).
价 格：￥电议型 号：T62976产 地：中国大陆
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T62975Haloperidol lactate；化合物 Haloperidol lactateHaloperidol lactate
Haloperidol lactate is a potent antipsychotic. haloperidol lactate has potential for studies in psychiatric disorders. haloperidol lactate can be used in acute and chronic schizophrenia and polyarousal syndrome.
价 格：￥电议型 号：T62975产 地：中国大陆
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T62974Pactimibe sulfate；化合物 Pactimibe sulfatePactimibe sulfate
Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor, acting on ACAT1 (IC50: 4.9 μM) and ACAT2 (IC50: 3.0 μM). Pactimibe sulfate inhibited oleoyl-CoA non-competitively (Ki: 5.6 μM) and significantly inhibited cholesterol ester formation (IC50: 6.7 μM). Pactimibe sulfate reduces plasma cholesterol activity and has anti-atherogenic potential.
价 格：￥电议型 号：T62974产 地：中国大陆
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T62973DS-3801b；化合物 DS-3801bDS-3801b
DS-3801b is a potent, non-macrolide GPR38 agonist and has the potential to be a novel gastrointestinal agonist for the study of functional gastrointestinal disorders (e.g. gastroparesis, chronic constipation).
价 格：￥电议型 号：T62973产 地：中国大陆
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T62972α-Glucosidase-IN-17；化合物 α-Glucosidase-IN-17α-Glucosidase-IN-17
α-Glucosidase-IN-17 (Compound 12B) is a potent and orally active inhibitor of α-glucosidase, demonstrating antidiabetic activity with an inhibitory concentration (IC50) of 3.79 μM [1].
价 格：￥电议型 号：T62972产 地：中国大陆
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T62971Tubulin polymerization-IN-16；化合物 Tubulin polymerization-IN-16Tubulin polymerization-IN-16
Tubulin aggregation-IN-16 (compound 5g) is a potent inhibitor of tubulin aggregation. 16 effectively disrupts microtubule/tubulin dynamics and induces cell cycle arrest at G2/M phase in SGC-7901 cells.
价 格：￥电议型 号：T62971产 地：中国大陆
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T62970CDK1-IN-1；化合物 CDK1-IN-1CDK1-IN-1
CDK1-IN-7 is a potent inhibitor of CDK1 with an IC50 value of 161.2 nM for CDK1/CycB. CDK1-IN-7 induces apoptosis in a p53-dependent manner via the apoptosis-intrinsic pathway. CDK1-IN-7 selectively acts on tumour tissue and has potential anti-proliferative effects. CDK1-IN-7 is a potential CDK1-IN-7 is a potential targeted anti-tumour agent.
价 格：￥电议型 号：T62970产 地：中国大陆
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T6297Alvespimycin hydrochloride；阿螺旋霉素盐酸盐BMS 826476|||NSC 707545|||KOS-1022|||17-DMAG hydrochloride|||Alve
Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.
价 格：￥电议型 号：T6297产 地：中国大陆
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T62969PDE4-IN-6；化合物 PDE4-IN-6PDE4-IN-6
PDE4-IN-6 is a safe, potent and moderately selective inhibitor of PDE4, acting on PDE4B (IC50: 0.125 μM) and PDE4D (IC50: 0.43 μM). PDE4-IN-6 is able to down-regulate TNF-α and IL-6 expression levels, exhibits anti-inflammatory and anti-arthritic effects, and has potent immunomodulatory activity. PDE4-IN-6 has potential for anti-rheumatoid arthritis studies.
价 格：￥电议型 号：T62969产 地：中国大陆
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T62968PPARα/δ agonist 1；化合物 PPARα/δ agonist 1PPARα/δ agonist 1
PPARα/δ agonist 1 is a potent PPARα/PPARδ dual agonist with EC50 values of 7.0 nM for PPARα and 8.4 nM for PPARδ. PPARα/δ agonist 1 exhibits high selectivity for PPARγ (EC50: 1316.1 nM). agonist 1 has potential for non-alcoholic steatohepatitis studies.
价 格：￥电议型 号：T62968产 地：中国大陆
