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T62952Estrogen receptor antagonist 5;化合物 Estrogen receptor antagonist 5Estrogen receptor antagonist 5
Estrogen receptor antagonist 5 is a potent antagonist of the Estrogen receptor. Estrogen receptor (Estrogen receptor) is a ligand-activated transcriptional regulatory protein that interacts with endogenous estrogens and mediates the induction of a variety of biological effects. estrogen receptor antagonist 5 has potential for metastatic disease studies.
价 格:¥电议型 号:T62952产 地:中国大陆
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T62946Dopamine D3 receptor antagonist-2;化合物 Dopamine D3 receptor antagonist-2Dopamine D3 receptor antagoni
Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.
价 格:¥电议型 号:T62946产 地:中国大陆
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T62944CCR8 antagonist 2;化合物 CCR8 antagonist 2CCR8 antagonist 2
CCR8 antagonist 2 is a potent antagonist of CCR8 that inhibits the activity of CCR8 (C-C Motif chemokine receptor 8), which is predominantly expressed on Treg and Th2 cells, and not on Th1 cells. CCR8 antagonist 2 can be used for the treatment of CCR8-mediated diseases (e.g. cancer and/or neuropathic pain).
价 格:¥电议型 号:T62944产 地:中国大陆
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T62918GPR84 antagonist 3;化合物 GPR84 antagonist 3GPR84 antagonist 3
GPR84 Antagonist 3 (compound 42), a potent inhibitor of the G-protein-coupled receptor 84 (GPR84), exhibits a pIC50 value of 8.28, indicating strong antagonistic activity by inhibiting GTPγS. Additionally, it possesses a favorable pharmacokinetic profile, suitable for further research and development [1].
价 格:¥电议型 号:T62918产 地:中国大陆
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T62858hGPR91 antagonist 3;hGPR91拮抗剂3hGPR91 antagonist 3
hGPR91 antagonist 3 is an orally active, potent, and selective hGPR91 antagonist. hGPR91 antagonist 3 is used to study hypertension, autoimmune diseases, and retinal angiogenesis. hGPR91 antagonist 3 has been shown to be effective in the treatment of hypertension, autoimmune disease, and retinal angiogenesis.
价 格:¥电议型 号:T62858产 地:中国大陆
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T62845NRP1 antagonist 2;化合物 NRP1 antagonist 2NRP1 antagonist 2
NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.
价 格:¥电议型 号:T62845产 地:中国大陆
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T628435-HT1A antagonist 1;化合物 5-HT1A?antagonist 15-HT1A antagonist 1
5-HT1A antagonist 1 (compound 6f) is a potent and selective 5-HT1Areceptor antagonist (Ki: 35 nM). 5-HT1A antagonist 1 can be used in the study of central nervous system disorders.
价 格:¥电议型 号:T62843产 地:中国大陆
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T62838AR antagonist 4;化合物 AR antagonist 4AR antagonist 4
AR antagonist 4 (Compound 67-b) is an orally active androgen receptor (AR) antagonist that acts on wild-type AR (IC50: 246.6 nM).
价 格:¥电议型 号:T62838产 地:中国大陆
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T62797A2A receptor antagonist 3;化合物 A2A receptor antagonist 3A2A receptor antagonist 3
A2A receptor antagonist 3 (Example 92) is an adenosine A2a receptor antagonist (Ki: 0.4 nM). receptor (Ki: 1467 nM).
价 格:¥电议型 号:T62797产 地:中国大陆
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T62768Mu opioid receptor antagonist 4;化合物 Mu opioid receptor antagonist 4Mu opioid receptor antagonist 4
Mu opioid receptor antagonist 4 (compound 31) is a potent and selective mu opioid receptor (MOR) antagonist that permeates the blood-brain barrier (Ki: 0.38 nM, EC50: 0.38 nM). Mu opioid receptor antagonist 2 can be used to study opioid use disorder (OUD).
价 格:¥电议型 号:T62768产 地:中国大陆
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T62767Mu opioid receptor antagonist 3;化合物 Mu opioid receptor antagonist 3Mu opioid receptor antagonist 3
Mu opioid receptor antagonist 3 (compound 26) is a potent and selective mu opioid receptor (MOR) antagonist that penetrates the blood-brain barrier (Ki: 0.24 nM, EC50: 0.54 nM). Mu opioid receptor antagonist 2 can be used to study opioid use disorder (OUD).
价 格:¥电议型 号:T62767产 地:中国大陆
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T62766Mu opioid receptor antagonist 2;化合物 Mu opioid receptor antagonist 2Mu opioid receptor antagonist 2
Mu opioid receptor antagonist 2 (compound 25) is a potent and selective mu opioid receptor (MOR) antagonist that permeates the blood-brain barrier (Ki: 0.37 nM, EC50: 0.44 nM). Mu opioid receptor antagonist 2 can be used to study opioid use disorder (OUD).
价 格:¥电议型 号:T62766产 地:中国大陆
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T62764Estrogen receptor α antagonist 1;化合物 Estrogen receptor α antagonist 1Estrogen receptor α antagonist
Estrogen receptor α antagonist 1 (compound 35) is a highly selective estrogen receptor α antagonist that acts on estrogen receptor α (IC50: 0.02 μM), estrogen receptor β (IC50. Estrogen receptor α antagonist 1 (compound 35) can be used to study tumours.
价 格:¥电议型 号:T62764产 地:中国大陆
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T62727NRP1 antagonist 1;化合物 NRP1 antagonist 1NRP1 antagonist 1
NRP1 antagonist 1 (compound 12a) is a potent antagonist of NRP1 (IC50: 19.1 μM).
价 格:¥电议型 号:T62727产 地:中国大陆
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T62673Mu opioid receptor antagonist 5;化合物 Mu opioid receptor antagonist 5Mu opioid receptor antagonist 5
Mu opioid receptor antagonist 5 (compound NAP) is a selective mu opioid receptor (MOR) antagonist that crosses the blood-brain barrier (EC50: 1.14 nM, Ki: 0.37 nM). Mu opioid receptor antagonist 5 can be used to study opioid use disorder (OUD).
价 格:¥电议型 号:T62673产 地:中国大陆
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T62641EP2 receptor antagonist-1;化合物 EP2 receptor antagonist-1EP2 receptor antagonist-1
EP2 receptor antagonist-1 is a reversible, potent, agonist-dependent variant of the prostaglandin EP2 receptor antagonist.EP2 receptor antagonist-1 exhibits anti-inflammatory activity.
价 格:¥电议型 号:T62641产 地:中国大陆
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T62631CB2 receptor antagonist 1;化合物 CB2 receptor antagonist 1CB2 receptor antagonist 1
Hexyl resorcinol derivative 29 is a CB2 selective competitive antagonist/reverse agonist demonstrating notable potency. Meanwhile, Olivanol and 5-(2-methyloctane-2-yl) resorcinol derivatives 23 and 24 exhibit substantial antinociceptive effects. Notably, compound 24 activates both cannabinoid and TRPV1 receptors.
价 格:¥电议型 号:T62631产 地:中国大陆
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T62611Adenosine receptor antagonist 2;化合物 Adenosine receptor antagonist 2Adenosine receptor antagonist 2
Adenosine receptor antagonist 2 is an orally active A2a (IC50: 1 nM), A2b (IC50: 3 nM) adenosine receptor antagonist that exhibits antitumour effects.
价 格:¥电议型 号:T62611产 地:中国大陆
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T62507Protease-Activated Receptor-1 antagonist 1;化合物 Protease-Activated Receptor-1 antagonist?1Protease-Ac
Protease-Activated Receptor-1 antagonist 1 (Compound 13) is a protease-activated receptor 1 (PAR-1) antagonist with an IC50 of 3 nM obtained by the FLIPR technique. antagonist 1 can be used to study thrombotic cardiovascular, myocardial infarction and peripheral arterial disease.
价 格:¥电议型 号:T62507产 地:中国大陆
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T62488P2X7 receptor antagonist-1;化合物 P2X7 receptor antagonist-1P2X7 receptor antagonist-1
P2X7 receptor antagonist-1 is a purinergic P2X7 receptor antagonist with anti-neuroinflammatory effects.
价 格:¥电议型 号:T62488产 地:中国大陆