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T21578NSC 66811;7-(ALPHA-苯胺基苄基)-2-甲基-8-喹啉醇NSC 66811
NSC 66811is a novel inhibitor of the murine double minute 2 (MDM2)-p53 interaction. It binds to MDM2 with a Ki of 120 nM and activates p53 in cancer cells with a mechanism of action consistent with targeting the MDM2-p53 interaction.
价 格:¥电议型 号:T21578产 地:中国大陆
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T21532Anisodamine;山莨菪碱6-Hydroxyhyoscyamine|||6-beta-Hydroxyhyoscyamine;6-Hydroxyhyoscyamine|||6-beta-Hydro
Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation in states of shock and can be used in studies about organophosphate poisoning.
价 格:¥电议型 号:T21532产 地:中国大陆
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T21452Anecortave Acetate;化合物Anecortave AcetateRetaane|||Al 3789|||NSC 24345|||NSC 15475|||Anecortave;Retaa
Anecortave Acetate (NSC-24345), an angiostatic steroid, is used for proteomics research.
价 格:¥电议型 号:T21452产 地:中国大陆
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T2145Temsirolimus;西罗莫司脂化物NSC 683864|||CCI-779;NSC 683864|||CCI-779|||西罗莫司脂化物
Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.
价 格:¥电议型 号:T2145产 地:中国大陆
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T21447Tolazoline;妥拉苏林Priscol|||Priscoline|||Pridazole|||Divascol|||Vasimid|||Benzalolin;Priscol|||妥拉苏林|||P
Tolazoline (Benzalolin), a non-selective competitive α-adrenergic receptor antagonist, is used as a vasodilator to treat spasms of peripheral blood vessels. It has also been used successfully as an antidote to reverse the severe peripheral vasoconstriction as a result of overdose with certain 5-HT2A agonist drugs.
价 格:¥电议型 号:T21447产 地:中国大陆
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T21435Sulfamoxole;磺胺二甲唑NSC 683535|||Oxasulfa|||Sulfamoxol|||NSC683535|||Oxazole|||NSC-683535;磺胺二甲唑|||NSC 6
Sulfamoxole (Sulfamoxol) is an antibacterial belonging to sulfonamide.
价 格:¥电议型 号:T21435产 地:中国大陆
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T21434Sulfacetamide;磺胺醋酰NSC 63871|||NSC-63871|||Sebizon|||Region|||NSC63871|||Sulphacetamide|||Acetosulfam
Sulfacetamide (NSC-63871) is used to treat blepharitis or conjunctivitis (in eye-drop solution) by limiting the presence of folic acid which bacteria need to survive. sulfacetamide may serve as a treatment for mild forms of hidradenitis suppurativa. It is also used to control acne.
价 格:¥电议型 号:T21434产 地:中国大陆
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T21424Disopyramide phosphate;化合物 T21424SC13957|||SC 13957|||SC-13957;SC13957|||SC 13957|||SC-13957
Disopyramide, a sodium channel blocker in the Class of 1a anti-arrhythmic agent, is used in the treatment of Ventricular Tachycardia. Disopyramide has a negative inotropic effect on the ventricular myocardium, resulting in a significant decrease in contractility.
价 格:¥电议型 号:T21424产 地:中国大陆
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T21405Fluvastatin;氟伐他汀Canef|||XU-62320|||Vastin|||Cranoc|||Lescol;Canef|||XU-62320|||Vastin|||Cranoc|||Les
Fluvastatin (XU-62320) is a potent and competitive HMG-CoA reductase inhibitor (IC50: 8 nM) that inhibits oxidative stress in vascular smooth muscle cells through an Nrf2-dependent pathway, and is used for the reduction of plasma cholesterol levels and the prevention of cardiovascular disease.
价 格:¥电议型 号:T21405产 地:中国大陆
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T21361Alclometasone dipropionate;阿氯米松双丙酸酯Vaderm|||Sch 22219|||Aclovate|||Delonal;Vaderm|||Sch 22219|||Aclo
Alclometasone dipropionate (Sch 22219) is a synthetic glucocorticoid, a steroidal compound with antiproliferative, anti-inflammatory, anti-allergic, antipruritic, and vasoconstrictive properties, which is used in the study of skin inflammation.
价 格:¥电议型 号:T21361产 地:中国大陆
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T21351Maytansine;美坦新NSC-153858|||NSC153858|||Maitansina|||NSC 153858|||Maitansine;NSC-153858|||NSC153858||
Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
价 格:¥电议型 号:T21351产 地:中国大陆
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T21335Fluorogestone acetate;氟孕酮醋酸酯Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880;F
Fluorogestone acetate (Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880) showed a high potency with short duration of activity and performed physiologically similar to progesterone. FGA was approximately 20 - 25 times more potent than progesterone.
价 格:¥电议型 号:T21335产 地:中国大陆
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T21316Apaziquone;化合物 T21316EO-9|||NSC382459|||EO9|||NSC 382459|||EO 9|||NSC-382459;EO-9|||NSC382459|||EO9|
Apaziquone has potential antineoplastic and radiosensitization activities. It is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death.
价 格:¥电议型 号:T21316产 地:中国大陆
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T21313Ametantrone;化合物 T21313CI881|||NSC-196473|||ametantrone diacetate|||NSC196473|||NSC 287513;CI881|||NS
Ametantrone (AM), a synthetic 9,10-anthracenedione bearing two ethylamino residues at positions 1 and 4, is the second anthracene derivative to enter clinical trials.
价 格:¥电议型 号:T21313产 地:中国大陆
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T21307Heptaplatin化合物 T21307NSC644591 NSCD644591 SKI2053R|||Heptaplatin Sunpla|||HTP
Heptaplatin, a new platinum derivative with anticancer activity, is used against various cancer cell lines, including cisplatin-resistant cancer cell lines. It has been reported to have a response rate of 17% as a single agent, and tolerable toxicity in the treatment of advanced gastric cancer.
价 格:¥电议型 号:T21307产 地:中国大陆
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T2118SC-514;化合物SC-514GK 01140;GK 01140
SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.
价 格:¥电议型 号:T2118产 地:中国大陆
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T21158Decanedioic acid, diethyl ester;化合物 T21158Diethyl sebacate|||NSC 8911;Diethyl sebacate|||NSC 8911
Decanedioic acid, diethyl ester is a biochemical.
价 格:¥电议型 号:T21158产 地:中国大陆
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T21122Decane, 1,1’-thiobis-;化合物 T21122AI3-12173|||NSC 408645|||Didecyl sulfide|||11-Thiaheneicosane;AI3-12
Decane, 1,1´-thiobis- is a biochemical.
价 格:¥电议型 号:T21122产 地:中国大陆
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T21108Triclopyr绿草定绿草定|||NSC-190671|||NSC 190671|||NSC190671
Triclopyr, a systemic foliar herbicide and fungicide, is used to control broadleaf weeds while leaving grasses and conifers unaffected or to control rust diseases on crops.
价 格:¥电议型 号:T21108产 地:中国大陆
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T21094Pseudopelletierine free base;化合物 T21094NSC 116056|||Granatonine|||Pseudopelletierine|||Granatan-3-on
Pseudopelletierine is the main alkaloid derived from the root-bark of Punica granatum, along with at least three other alkaloids: isopelletierine, methylpelleteirine (C9H17ON) and pelletierine, which yield 1.8, 0.01, 0.20 and 0.52 grams per kilogram of raw bark.
价 格:¥电议型 号:T21094产 地:中国大陆