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T22767ER 50891;化合物ER 50891ER 50891
ER-50891 is a potent retinoic acid receptor alpha (RARα) antagonist. er-50891 reduces the inhibitory effect of allosteric retinoic acid and restores osteoblast differentiation induced by bone morphogenetic protein 2.
价 格:¥电议型 号:T22767产 地:中国大陆
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T22691CP 99994 dihydrochloride;化合物 T22691CP 99994 dihydrochloride
High affinity NK1 antagonist
价 格:¥电议型 号:T22691产 地:中国大陆
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T22591ATC 0175 hydrochloride;ATC 0175 盐酸盐ATC 0175 hydrochloride
ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affinity for MCH1R, MCH2R, MCH1, 5-HT2B receptors and 5-HT1A receptors with IC50s of 13.5 nM, >10,000 nM, 13 nM, 9.66 nM and 16.9 nM, respectively. ATC 0175 hydrochloride exhibits antidepressant and anxiolytic effects in animal models. aTC 0175 can be used to study depression and/or anxiety disorders.
价 格:¥电议型 号:T22591产 地:中国大陆
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T22491PDE7-IN-2;化合物 PDE7-IN-2PDE7-IN-2
PDE7-IN-2 is an inhibitor of phosphodiesterase 7 (IC50 = 2.1 ?M) and can be used in Parkinson´s disease studies.
价 格:¥电议型 号:T22491产 地:中国大陆
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T224691-Methylpsilocin;化合物 T224691-Methylpsilocin
5-HT2C agonist, potent and selective
价 格:¥电议型 号:T22469产 地:中国大陆
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T22391Omeprazole Sodium;奥美拉唑钠Omeprazole Sodium
Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole Sodium inhibits growth of Gram-positive and Gram-negative bacteria.
价 格:¥电议型 号:T22391产 地:中国大陆
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T22301L-838417 D9;化合物L-838417 D9CTP354|||CTP354 (C-21191)|||C-21191;CTP354|||CTP354 (C-21191)|||C-21191
L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].
价 格:¥电议型 号:T22301产 地:中国大陆
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T22291Chitin甲壳素Chitin (From shrimp and crab shells)
Chitin is a large, structural polysaccharide found in the cell walls of fungi, the exoskeletons of insects, and certain hard structures in fish and invertebrates.
价 格:¥电议型 号:T22291产 地:中国大陆
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T22251680C91;化合物680C91680C91
680C91 is a potent and selective inhibitor of TDO, and its Ki is 51 nM.
价 格:¥电议型 号:T22251产 地:中国大陆
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T22142RO8191;化合物RO8191RO4948191|||CDM-3008;RO4948191|||CDM-3008
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
价 格:¥电议型 号:T22142产 地:中国大陆
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T22104ML-291;化合物 T22104ML-291
ML291 is a sufonamidebenzamide compound that induces the unfolded protein response (UPR) and overwhelms the adaptive capacity of UPR, resulting in apoptosis in various solid cancer models. It activates the PERK/eIF2a/CHOP apoptotic pathway of UPR and reduces leukemic cell burden [1].
价 格:¥电议型 号:T22104产 地:中国大陆
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T22091Imiquimod hydrochloride;化合物 T22091Imiquimod hydrochloride
Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties. It is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2].
价 格:¥电议型 号:T22091产 地:中国大陆
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T21919UCF 101;化合物UCF 101UCF 101
UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.
价 格:¥电议型 号:T21919产 地:中国大陆
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T21916TC-SP 14;化合物 T21916TC-SP 14
TC-SP 14, also known as compound 14, is a highly active and potent S1P1 agonist with oral bioavailability. It exhibits an EC50 value of 0.042 μM, indicating its strong binding affinity to the S1P1 receptor. Notably, its interaction with the S1P3 receptor is minimal, as evidenced by an EC50 value of 3.47 μM. TC-SP 14 demonstrates significant pharmacological effects, including a marked reduction in blood lymphocyte counts and the attenuation of delayed type hypersensitivity response to antigen cha
价 格:¥电议型 号:T21916产 地:中国大陆
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T21915TBCA;化合物TBCACasein Kinase II Inhibitor III, TBCA;Casein Kinase II Inhibitor III, TBCA
TBCA (Casein Kinase II Inhibitor III, TBCA) is a highly selective CK2 (casein kinase II) inhibitor, IC50 = 110 nM, Ki = 77 nM. TBCA shows selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases.
价 格:¥电议型 号:T21915产 地:中国大陆
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T21914(S)-SLV 319;化合物 T21914(S)-SLV 319
Ibipinabant (SLV319) is a potent, selective, and orally active antagonist of the cannabinoid CB1 receptor, demonstrating a K i of 7.8 nM and exhibiting over 1000-fold selectivity for CB1 compared to CB2 (K i =7943 nM). It is utilized in obesity and diabetes research [1] [2] [3].
价 格:¥电议型 号:T21914产 地:中国大陆
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T21911Rilmenidine hemifumarate;利美尼定半富马酸盐Rilmenidine (hemifumarate)|||S-3341 hemifumarate;Rilmenidine (hemi
Rilmenidine hemifumarate (S-3341 hemifumarate) is a novel, orally active and selective I1 imidazoline receptor and α2-adrenoceptor agonist that induces autophagy, regulates the proliferation of leukaemia cells, stimulates the pro-apoptotic protein Bax, and induces autophagy in human leukaemia K5 cells. induces disruption of the mitochondrial pathway and apoptosis in human leukaemia K562 cells.
价 格:¥电议型 号:T21911产 地:中国大陆
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T2191Tacrine hydrochloride (hydrate);他克林盐酸盐水合物Tacrine|||Tacrine hydrochloride hydrate|||Tetrahydroaminacr
Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer´s disease and other central nervous system disorders.
价 格:¥电议型 号:T2191产 地:中国大陆
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T21839L10Panx Acetate;化合物10Panx Acetate10Panx Acetate(955091-53-9 Free base);10Panx Acetate(955091-53-9 Fre
10Panx Acetate is a mimetic inhibitory peptide that readily and reversibly inhibits the panx1 currents.
价 格:¥电议型 号:T21839L产 地:中国大陆
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T21821LREV 5901A;化合物 REV 5901AREV 5901 HCl|||REV 5901A(101910-24-1 Free base);REV 5901 HCl|||REV 5901A(1019
REV 5901A (REV 5901 HCl) is an orally active leukotriene receptor antagonist and 5-lipoxygenase inhibitor with antimicrobial activity that attenuates colon cancer growth in mice.REV 5901A has been used in studies of asthma and myocardial infarction. REV 5901A is used to study asthma and myocardial infarction.
价 格:¥电议型 号:T21821L产 地:中国大陆