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T22665PD 128042;化合物CI 976CI 976;CI 976
PD 128042 (CI 976) is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor. CI 976 inhibits Golgi-associated LPAT activity (IC50: 15 μM) and multiple membrane trafficking steps.
价 格:¥电议型 号:T22665产 地:中国大陆
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T22597Bafetinib (INNO-406);化合物 T22597Bafetinib (INNO-406)
Bafetinib is a potent and selective dual inhibitor of Bcr-Abl/Lyn tyrosine kinase (IC50: 5.8nM and 19nM, respectively).
价 格:¥电议型 号:T22597产 地:中国大陆
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T224972-MPPA;化合物 T224972-MPPA
glutamate carboxypeptidase II (GCP II) inhibitor
价 格:¥电议型 号:T22497产 地:中国大陆
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T22440TP-353;化合物TP-353EOS-61973;EOS-61973
TP-353 (EOS-61973) is a CDK7 inhibitor.
价 格:¥电议型 号:T22440产 地:中国大陆
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T22397PF-4618433化合物PF-4618433PF4618433|||PF 4618433
PF-4618433 is a dual inhibitor of focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2).
价 格:¥电议型 号:T22397产 地:中国大陆
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T22393Palonosetron;帕洛诺司琼RS25259|||RS 25259 197;RS25259|||帕洛诺司琼|||RS 25259 197
Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
价 格:¥电议型 号:T22393产 地:中国大陆
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T22342GSK3368715 3HCl;化合物GSK3368715 (EPZ019997) 3HClEPZ019997 3HCl|||GSK3368715(EPZ019997);EPZ019997 3HCl|
GSK3368715, a potent inhibitor of type I protein arginine methyltransferases (PRMT), could inhibit PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM.
价 格:¥电议型 号:T22342产 地:中国大陆
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T22297Clindamycin hydrochloride monohydrate盐酸克林霉素Clindamycin alcoholate
Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentrations (sub-MICs). It acts by suppressing Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), and alpha-haemolysin (Hla) production. Resistance to this compound emerges through enzymatic methylation at the antibiotic´s 50S ribosomal subunit binding
价 格:¥电议型 号:T22297产 地:中国大陆
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T222505WKS;化合物5WKSZINC97756584;ZINC97756584
5WKS also known as ZINC97756584 is a biochemical. It is a G9a protein inhibitor.G9A/EHMT2 is a nuclear histone lysine methyltransferase that catalyzes H3K9me2, a reversible modification commonly associated with transcriptional gene silencing.5WKS can be used in the study of autoimmune diseases or tumors.
价 格:¥电议型 号:T22250产 地:中国大陆
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T22197CFM 1571 hydrochloride化合物 T22197CFM 1571 hydrochloride
CFM 1571 hydrochloride is a chemical compound that acts as a stimulator of the nitric oxide receptor known as soluble guanylate cyclase (sGC). It demonstrates an EC50 value of 5.49 μM and an IC50 value of 2.84 μM. Soluble guanylate cyclase is an important signal-transduction enzyme that is activated by nitric oxide. The compound CFM 1571 hydrochloride shows potential for use in cardiovascular and other disease research [1] [2].
价 格:¥电议型 号:T22197产 地:中国大陆
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T21999(±)-J 113397;化合物 T21999(±)-J 113397
(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM). J-113397 inhibited nociceptin/orphanin FQ-stimulated GTPγS binding to CHO cells expressing ORL1 with an IC 50 value of 5.3 nM. J-113397 can be used for researching the physiological roles of nociceptin/orphanin FQ [1].
价 格:¥电议型 号:T21999产 地:中国大陆
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T21996Zoniporide hydrochloride;化合物ZoniporideCP-597396 hydrochloride;CP-597396 hydrochloride
Zoniporide hydrochloride is a selective inhibitor of NHE-1 with IC50 of 14 nM which is >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride shows an IC50 of 59 nM for NHE-1-dependent swelling of human platelets.
价 格:¥电议型 号:T21996产 地:中国大陆
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T21979P32/98 hemifumarate;异亮氨酸噻唑烷半富马酸盐P32/98 (hemifumarate)(136259-20-6 free base);P32/98 (hemifumarate)(1
P32/98 hemifumarate is a dipeptidyl peptidase IV (DPP4) inhibitor with hypoglycemic properties that improves insulin sensitivity and β-cell responsiveness in the Zucker diabetic rat model, and may be useful in studies of type 2 diabetes and colitis.
价 格:¥电议型 号:T21979产 地:中国大陆
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T21978p-nitro-Pifithrin-α;化合物 T21978p-nitro-Pifithrin-α
p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor. It suppresses p53-mediated TGF-β1 expression in HK-2 cells and inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. Moreover, p-nitro-Pifithrin-α attenuates steatosis and liver injury in mice subjected to a high-fat diet, mitigating the effects of non-alcoholic fatty liver disease [1] [2] [3] [4].
价 格:¥电议型 号:T21978产 地:中国大陆
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T21977p-Cresyl sulfate;化合物p-Cresyl sulfatep-Cresyl sulfate
p-Cresyl Sulfate is a major uremic toxin found in the blood of patients with chronic kidney disease (CKD), derived from the metabolites of tyrosine and phenylalanine in the liver.
价 格:¥电议型 号:T21977产 地:中国大陆
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T21976ONO-8130;化合物ONO-8130ONO-8130
ONO-8130 is an orally available antagonist of EP1 receptor.
价 格:¥电议型 号:T21976产 地:中国大陆
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T21970ML-097;化合物ML-097ML-097
ML-097 (CID-2160985) is a pan activator of Ras-related GTPases
价 格:¥电议型 号:T21970产 地:中国大陆
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T219710-Deacetylbaccatin III10-脱乙酰巴卡丁 III10-脱乙酰巴卡丁 III|||10-脱乙酰基巴卡丁III
10-Deacetylbaccatin-III is an intermediate for taxol analog preparations with anti-cancer activity.
价 格:¥电议型 号:T2197产 地:中国大陆
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T21897LMPP hydrochloride;化合物MPP hydrochlorideMPP hydrochloride (289726-02-9 Free base);MPP hydrochloride (2
MPP hydrochloride is a selective estrogen receptor (ERR) modulator.
价 格:¥电议型 号:T21897L产 地:中国大陆
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T21897Methylpiperidino pyrazole;甲基哌啶基吡唑Methylpiperidino pyrazole
Methylpiperidino pyrazole is an ERα inhibitor and can prevent the BPS-induced Rb phosphorylation and cell cycle progression.
价 格:¥电议型 号:T21897产 地:中国大陆